GTPαS

Catalog No.: A56541
Nucleoside Analog
GTPαS is a stable analog of guanosine triphosphate (GTP) that acts as a substrate for nucleic acid synthesis. It is predominantly utilized in cellular signaling studies and can inhibit GTPase activities, serving as a valuable tool in examining the functions of GTP-binding proteins. Its applications extend to investigations in molecular biology, particularly in the study of gene expression and regulatory mechanisms.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGTPαS is a stable analog of guanosine triphosphate (GTP) that acts as a substrate for nucleic acid synthesis. It is predominantly utilized in cellular signaling studies and can inhibit GTPase activities, serving as a valuable tool in examining the functions of GTP-binding proteins. Its applications extend to investigations in molecular biology, particularly in the study of gene expression and regulatory mechanisms.
Product Information
Catalog NumA56541
FormulaC10H16N5O13P3S
Molecular Weight539.25
CAS Number71376-96-0
SMILESO[C@H]1[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(S)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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