DNA Damage

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  1. Nucleoside Analog

    2'-O-TBDMS-rG(iBu) is a nucleoside analog featuring a tert-butyldimethylsilyl (TBDMS) protecting group at the 2'-position of riboguanosine. This compound serves as a valuable monomer for nucleic acid synthesis, facilitating the construction of modified RNA sequences. Its ability to enhance stability and influence the hybridization properties of RNA oligonucleotides makes it a useful tool in various molecular biology applications, including RNA therapeutics and gene regulation studies.
  2. Nucleoside Analog

    5'-O-TBDMS-3'-O-TBDMS-5-I-dC is a nucleoside analog designed for use in nucleic acid synthesis. Its TBDMS (tert-butyldimethylsilyl) protection groups enhance stability during the synthesis process. This reagent is ideal for constructing oligonucleotides and exploring nucleic acid structures in various biochemical studies.
  3. Nucleoside Analog

    4'-O-CH2-phosphate methyl ester-2'-O-Me-rU-3'-CE-phosphoramidite is a nucleoside analog designed for the synthesis of modified nucleic acids. Its unique structure enhances incorporation into oligonucleotides, contributing to novel properties and stabilization. This reagent is suitable for applications in the development of therapeutics, antisense oligonucleotides, and RNA-based research.
  4. Nucleoside Analog

    3'-OMe-m7GDP is a nucleoside analog that serves as a critical building block for nucleic acid synthesis. Its modified ribose moiety enhances stability against degradation, making it a valuable reagent for studies involving RNA synthesis and modifications. This compound is applicable in various fields, including molecular biology and genetic research, where precise nucleic acid constructs are essential.
  5. Nucleoside Analog

    2'-F-dUTP (2'-Fluoro-dUTP) is a nucleoside analog that serves as a key building block for the synthesis of nucleic acids. Its incorporation into oligonucleotides can enhance stability and resistance to exonuclease degradation. This reagent is commonly used in applications such as PCR, oligonucleotide synthesis, and sequencing studies, where its unique properties can facilitate improved performance and specificity.
  6. Nucleoside Analog

    4'-O-Ac-3'-O-Bz-2'-O-Me-N3-Bz-U is a nucleoside analog that serves as a key monomeric building block for nucleic acid synthesis. This compound can be utilized in the development of oligonucleotides and various gene editing applications, facilitating studies in molecular biology and genetic engineering. Its chemical modifications enhance stability and lipophilicity, which may improve the delivery of nucleic acid therapeutics.
  7. Nucleoside Analog

    3'-O-Azidomethylene-dT is a nucleoside analog that serves as a key building block for nucleic acid synthesis. It features an azido group at the 3' position, which enables specific modifications in oligonucleotide design and synthesis. This compound is valuable in the study of nucleic acid interactions, probe development, and therapeutic applications in molecular biology and genetic research.
  8. Nucleoside Analog

    2',3'-Di-O-iBu-rG(iBu) is a nucleoside analog designed for use in nucleic acid synthesis. This compound serves as a valuable monomer in the construction of RNA molecules, providing unique chemical properties that can enhance stability and optimize performance in various biological assays. Its applications extend to research areas such as oligonucleotide synthesis and the development of RNA-based therapeutics.
  9. Nucleoside Analog

    (2'OMe-5'pp-m6A)pG is a nucleoside analog that acts as a modified guanosine monomer. This compound is primarily utilized in nucleic acid synthesis, enabling the incorporation of methylated adenosine modifications into RNA molecules. It plays a crucial role in the study of RNA structure and function, particularly in understanding m6A modification effects on gene regulation and biogenesis.
  10. Nucleoside Analog

    2′-OMe-UDP is a nucleoside analog that serves as a crucial intermediate in the synthesis of modified oligonucleotides. This compound exhibits enhanced stability and resistance to nuclease degradation, making it valuable for various nucleic acid research applications. Its incorporation into oligonucleotides facilitates studies in gene expression, RNA interference, and antisense therapy.
  11. Nucleoside Analog

    3'-ONH₂-dCTP is a nucleoside analog that serves as a substrate for DNA polymerases during nucleic acid synthesis. Its modified structure allows for incorporation into DNA, facilitating the study of biological processes and enabling the development of novel therapeutic strategies. This reagent is valuable for research applications in genetics, molecular biology, and biotechnology.
  12. Nucleoside Analog

    DMTr-2'-O-Bn-rU-3'-CE-phosphoramidite is a nucleoside analog that serves as a key building block for the synthesis of nucleic acids. With its unique protective groups, this phosphoramidite facilitates efficient incorporation into oligonucleotides, enabling researchers to create modified RNA structures. Its applications extend to studies in gene expression, RNA stability, and the exploration of novel therapeutics.
  13. Nucleoside Analog

    5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rA(Ac) is a nucleoside analog designed for use in nucleic acid synthesis. This compound serves as a versatile building block, facilitating the incorporation of modified nucleotides into oligonucleotides. Its unique chemical structure allows for enhanced stability and functionality in various genomic applications, making it suitable for research in fields such as molecular biology and genetic engineering.
  14. Nucleoside Analog

    DMTr-2'-O-Bn-rC(Ac)-3'-CE-phosphoramidite is a nucleoside analog that serves as a building block for nucleic acid synthesis. This reagent facilitates the incorporation of modified nucleotides into oligonucleotides, enhancing their stability and activity. Its applications include the development of antisense oligonucleotides and RNA interference technologies, making it valuable for research in gene expression regulation and therapeutic development.
  15. Nucleoside Analog

    3′-O-Azidomethyl-dTTP is a nucleoside analog that serves as a key building block in nucleic acid synthesis. Its azide functional group enables specific reactions for the incorporation of modified nucleotides into DNA strands. This reagent is essential for research applications involving genetic engineering, oligonucleotide synthesis, and the development of novel bioconjugates.
  16. Nucleoside Analog

    LNA-GTP is a nucleoside analog that serves as a critical building block for the synthesis of oligonucleotides. Its unique structural features enhance binding affinity and stability, making it suitable for applications in nucleic acid research, including gene expression studies and molecular diagnostics. This reagent is particularly useful in the development of locked nucleic acid (LNA)-modified oligonucleotides, which exhibit improved hybridization properties.
  17. Nucleoside Analog

    dCDP disodium is a nucleoside analog that serves as a key building block for nucleic acid synthesis. Its primary mechanism involves incorporation into DNA and RNA strands, where it acts as a substrate for polymerases. This reagent is essential for various molecular biology applications, including the study of nucleic acid structure and function, as well as in the development of therapeutic oligonucleotides.
  18. Nucleoside Analog

    2',5'-di-OBz-rC(Bz) is a nucleoside analog that serves as a key monomer for nucleic acid synthesis. Its structural modifications enhance base pairing and stability, facilitating the design of nucleic acids with tailored properties. This compound is particularly useful in research applications involving RNA synthesis, molecular biology, and therapeutic development.
  19. Nucleoside Analog

    LNA-GMP is a nucleoside analog that serves as a crucial building block in the synthesis of oligonucleotides. This compound enhances the stability and binding affinity of nucleic acid sequences, making it useful for applications in antisense oligonucleotide design, molecular diagnostics, and gene expression studies. Its unique properties enable researchers to develop more effective therapeutic agents and probe designs in nucleic acid research.
  20. Nucleoside Analog

    2'-Deoxy-3',5'-ADP is a nucleoside analog that serves as a fundamental building block for nucleic acid synthesis. This compound is essential for studies involving DNA and RNA manipulation, facilitating the synthesis of oligonucleotides and polydeoxynucleotides. Its incorporation into nucleic acid structures allows for the exploration of various biochemical pathways and the development of diagnostic tools.
  21. Nucleoside Analog

    DMTr-2'-O-Me-rA(Bz)-3'-(L)-PSM-phosphoramidite is a nucleoside analog that serves as a key monomer for nucleic acid synthesis. Its structures enable the incorporation of modified ribonucleotides into oligonucleotides, enhancing stability and biological functionality. This reagent is essential in various applications including the development of therapeutics, molecular probes, and antisense oligonucleotides.
  22. Nucleoside Analog

    6'-O-DMTr-2'-O-Me-5'-Homo-U-3'-CE-phosphoramidite is a nucleoside analog that serves as a versatile monomeric building block for oligonucleotide synthesis. Its unique chemical structure enables the incorporation of modified nucleotides, facilitating advanced applications in molecular biology and genetic research. This reagent is particularly useful in the design and synthesis of oligonucleotides for therapeutic and diagnostic purposes.
  23. Nucleoside Analog

    Biotin-16-aminoallyluridine-5'-triphosphate is a nucleoside analog that serves as a valuable substrate for RNA synthesis. This compound is utilized in various biochemical applications, including the labeling of nucleic acids, facilitating the detection and quantification of RNA molecules. Its incorporation into RNA can enhance the stability and functionality of synthesized transcripts for research purposes.
  24. Nucleoside Analog

    3'-ONH2-dTTP is a nucleoside analog that serves as a monomeric building block for the synthesis of nucleic acids. Its primary mechanism involves acting as a substrate for DNA polymerases, enabling the incorporation of modified nucleotides into DNA strands. 3'-ONH2-dTTP is utilized in various research applications, including studies on DNA structure-function relationships and the development of novel therapeutic agents.
  25. Nucleoside Analog

    2'-F-CMP is a nucleoside analog that serves as a substrate for the synthesis of oligonucleotides. Its incorporation into RNA sequences mimics the natural nucleotides, allowing for studies in RNA function and stability. This reagent is valuable in molecular biology research for generating modified oligonucleotides that confer unique properties in therapeutic and diagnostic applications.
  26. Nucleoside Analog

    CAP GAU m7G(5')ppp(5')(2'OMeA)pU is a nucleoside analog that serves as a critical monomer for nucleic acid synthesis. This compound is valuable in the development of modified RNA molecules and can be utilized in various applications such as the study of gene expression and the design of RNA-based therapeutics. Its unique structural features enhance stability and facilitate the exploration of RNA functionality in biochemical research.
  27. Nucleoside Analog

    DMTr-2'-O-(Methyl palmitate)-rU-3'-CE-phosphoramidite is a nucleoside analog utilized in the synthesis of oligonucleotides. This compound serves as a monomeric building block, enabling the incorporation of modified nucleotides into nucleic acid sequences. Its unique structure facilitates enhanced stability and solubility in various biochemical assays, supporting applications in molecular biology and genetic research.
  28. Nucleoside Analog

    5-Aminoallyl-dUTP is a nucleoside analog that serves as a building block for nucleic acid synthesis. Its incorporation into DNA allows for further functionalization and analysis, making it valuable in applications such as label-free detection, genetic engineering, and sequencing technologies. This reagent is ideal for researchers aiming to explore nucleic acid interactions and develop novel bioconjugates.
  29. Cytidine Analog

    2-Chloro-2'-deoxycytidine is a cytidine nucleoside analog that acts primarily by inhibiting DNA methyltransferases. This compound exhibits important biological activity, including anti-metabolic and anti-tumor effects. It is widely utilized in research applications focusing on epigenetic regulation, cancer biology, and the development of novel therapeutic strategies.
  30. Nucleoside Analog

    DMTr-2'-O-Me-rG(iBu)-3'-(D)-DPSE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite monomer enhances the stability and solubility of oligonucleotides, making it valuable in the development of complex nucleic acid structures. Its unique properties facilitate various research applications, including the synthesis of modified RNA and DNA sequences for therapeutic and diagnostic purposes.
  31. Nucleoside Analog

    6'-O-DMTr-2'-O-Me-5'-Homo-C(Ac)-3'-CE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite is suitable for synthesizing modified oligonucleotides with enhanced stability and specificity. It plays a crucial role in the development of therapeutic oligonucleotides and molecular probes, facilitating advancements in genetic research and drug discovery.
  32. Nucleoside Analog

    6'-O-DMTr-2'-O-Me-5'-Homo-G(iBu)-3'-CE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This monomeric reagent features unique modifications that enhance the stability and performance of the resulting oligonucleotides. It is applicable in various research applications, including gene synthesis and oligonucleotide-based therapies.
  33. Nucleoside Analog

    3'-OMe-m7GpppGmpG is a nucleoside analog that serves as a valuable monomeric raw material for nucleic acid synthesis. This compound is particularly useful in the development of modified RNA and DNA molecules, offering enhanced stability and biological activity. Its applications extend to research in gene expression, oligonucleotide design, and therapeutic development.
  34. Nucleoside Analog

    Nucleoside-analog-3 is a novel S-cEt guanosine intermediate that functions as a nucleoside analog. This compound exhibits key biological activities relevant to antiviral and anticancer research applications, facilitating the study of nucleoside metabolism and enabling the development of therapeutic strategies targeting nucleic acid synthesis. It serves as an essential tool for researchers investigating the mechanistic pathways of nucleoside-based therapeutics.
  35. Nucleoside Analog

    DMTr-2'-O-C16-rU-3'-CE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite serves as a monomeric building block, facilitating the incorporation of modified ribonucleotides into RNA sequences. Its unique structure enhances the stability and functionality of synthesized nucleic acids, making it suitable for various research applications, including gene expression studies and the development of RNA-based therapeutics.
  36. Nucleoside Analog

    7-Deaza-2'-dG, a nucleoside analog, serves as a crucial building block in nucleic acid synthesis. This compound is utilized in the production of modified oligonucleotides, enhancing the stability and activity of nucleic acids in various biochemical and genetic studies. Its application is particularly valuable in designing experiments involving antisense oligonucleotides and other therapeutic nucleic acid constructs.
  37. Nucleoside Analog

    (2'OMe-5'p(S)-A)pG is a nucleoside analog that serves as a monomeric substrate for nucleic acid synthesis. Its modified structure enhances stability and improves enzymatic properties, making it valuable for applications in RNA research and therapeutic development. This reagent is ideal for constructing modified oligonucleotides that can facilitate studies in gene expression, RNA interference, and other nucleic acid-related fields.
  38. Nucleoside Analog

    3'-ONH2-dATP is a nucleoside analog that serves as a substrate for DNA polymerase during nucleic acid synthesis. Its unique amine modification enhances the structural diversity of oligonucleotides, making it a valuable tool in research applications including genetic engineering, molecular cloning, and the development of modified nucleic acids. This reagent is ideal for studies investigating the effects of nucleotide modifications on enzymatic activity and stability of nucleic acids.
  39. Nucleoside Analog

    3′-O-Azidomethyl-dUTP is a nucleoside analog that serves as a substrate for nucleic acid synthesis. Its azide functionality allows for the incorporation into DNA strands, facilitating the introduction of modifications in genetic studies. This reagent is valuable for applications such as the synthesis of modified oligonucleotides and in bioconjugation techniques to visualize or manipulate nucleic acids in various research settings.
  40. Nucleoside Analog

    5-CF₃-ddUTP is a nucleoside analog that serves as a building block for nucleic acid synthesis. This compound is designed to incorporate into DNA and RNA strands, providing a unique fluorescence feature that enables detection and quantification in various assays. Its application extends to molecular biology, particularly in studies involving DNA polymerase activity and sequencing.
  41. Nucleoside Analog

    Biotin-11-dATP is a nucleoside analog that serves as a phosphoramidite for nucleic acid synthesis. This biotinylated deoxynucleotide enhances the detection and labeling of DNA and RNA molecules in various molecular biology applications. Its key biological activity includes facilitating the incorporation of biotin into oligonucleotides, making it an essential reagent for applications such as PCR, cloning, and in situ hybridization.
  42. Nucleoside Analog

    Rp-dCTPαS is a nucleoside analog that serves as a monomeric substrate for nucleic acid synthesis. It plays a crucial role in the study of DNA and RNA polymerization mechanisms and is utilized in various applications such as mutagenesis, primer extension, and the synthesis of modified nucleic acids. This compound is an essential tool for researchers working in molecular biology and genetics.
  43. Nucleoside Analog

    DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-(L)-PSM-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite derivative serves as a key building block for the construction of modified RNA and DNA oligonucleotides. Its unique structure enables enhanced stability and incorporation into various nucleic acid constructs, making it suitable for applications in molecular biology, genetic engineering, and therapeutic development.
  44. Nucleoside Analog

    3'-β-F-2'-5-Me-dU is a nucleoside analog designed for the synthesis of modified nucleic acids. This compound plays a crucial role in biochemical studies by facilitating the development of nucleic acid constructs with altered properties. Its incorporation into oligonucleotides can enhance stability and binding affinity, making it valuable for various applications in gene expression, drug development, and molecular biology research.
  45. Nucleoside Analog

    DMTr-2'-O-[2-(TFA)aminoethoxymethyl]-rA(Bz)-3'-CE-phosphoramidite is a nucleoside analog agent designed for oligomer synthesis. This phosphoramidite derivative facilitates the incorporation of modified nucleotides into RNA sequences, enhancing the structural and functional diversity of oligonucleotides. Its proficiency in nucleic acid synthesis makes it a valuable tool for molecular biology research, including applications in RNA therapeutics and genomic studies.
  46. Nucleoside Analog

    dGTPαS (2'-Deoxyguanosine-5'-O-(α-thio)triphosphate) serves as a nucleoside analog, specifically designed for incorporation into nucleic acids. This compound exhibits essential biological activity in the synthesis of oligonucleotides, providing researchers with a valuable tool for studying various aspects of nucleic acid chemistry and molecular biology. Its unique structure enables enhanced stability and modified properties that can aid in the design of novel nucleic acid constructs.
  47. Nucleoside Analog

    5-Aza-2'-deoxy-6-oxo cytidine is a nucleoside analog that serves as a valuable substrate for nucleic acid synthesis. This compound possesses structural modifications that enhance its stability and incorporation into DNA, making it a useful tool for studies involving epigenetics and gene expression regulation. Applications include the investigation of DNA methylation processes and the development of therapeutic strategies targeting nucleic acid sequences.
  48. Nucleoside Analog

    2-Amino-2'-O-methyladenosine is a nucleoside analog that serves as a valuable monomeric building block for nucleic acid synthesis. This compound is essential in biochemical research for the development of modified RNA molecules and offers insights into nucleic acid structure and function. Its unique chemical properties facilitate the investigation of RNA interactions and stability, making it a key reagent in the study of molecular biology and biochemistry.
  49. Nucleoside Analog

    2'-F T Amidite (DMTr-2'-F-dT-3'-CE-phosphoramidite) serves as a nucleoside analog in oligonucleotide synthesis. Its incorporation into nucleic acid sequences enhances thermal stability and binding affinity due to the fluorine substitution at the 2' position. This reagent is critical for studies involving RNA stability, gene expression modulation, and the development of antisense oligonucleotides.
  50. Nucleoside Analog

    CAP m7G(LNA)(5')ppp(5')A(LNA)pG is a modified nucleoside analog designed to enhance nucleic acid synthesis. It features a 7-methylguanylate structure, which serves as a cap for RNA molecules, facilitating increased stability and improved translation efficiency. This compound is ideal for research applications involving RNA synthesis, development of therapeutics, and studies on gene expression modulation.

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