DNA Damage

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  1. Nucleoside Analog

    Pyrrolo-dCTP is a nucleoside analog that serves as a monomeric raw material for nucleic acid synthesis. This compound is instrumental in the development of modified oligonucleotides, enabling enhanced stability and improved properties for various biochemical applications. Pyrrolo-dCTP is particularly valuable in studies focused on gene editing, antisense therapies, and other nucleic acid-based research methodologies.
  2. Nucleoside Analog

    Cbz-TRIS-PDA trihydrochloride is a trifunctional nucleoside analog featuring a Cbz protecting group, designed for use in oligonucleotide synthesis. This compound serves as a valuable reagent for modifying nucleic acids, facilitating the development of advanced therapeutic agents and research tools. Its unique properties enhance the efficiency and specificity of synthesis processes, making it an essential resource for molecular biology applications.
  3. Nucleoside Analog

    DMTr-5-Me-dC(C6-O-Lev)-3'-CE-phosphoramidite is a nucleoside analog that serves as a versatile building block for the synthesis of oligonucleotides. This modified phosphoramidite facilitates the incorporation of specific structural elements into nucleic acid sequences. Its unique properties make it suitable for applications in molecular biology, including the development of therapeutic nucleic acids and probes for gene expression studies.
  4. Nucleoside Analog

    5-Methoxyuridine-5'-triphosphate is a nucleoside analog that acts as a building block for nucleic acid synthesis. This compound exhibits key biological activity by incorporating into RNA, thus facilitating the study of RNA dynamics and function. It is useful for applications in molecular biology and genetic research, including the development of RNA-based therapeutics and assays.
  5. Nucleoside Analog

    DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite monomer facilitates the incorporation of modified nucleotides into oligonucleotide sequences, enhancing the stability and functionality of nucleic acids. It is particularly valuable in the development of antisense oligonucleotides and RNA-based therapeutics.
  6. Nucleoside Analog

    5'-O-DMTr-3'-β-OH-2'-5-Me-dU(Boc) is a nucleoside analog utilized in nucleic acid synthesis. This compound serves as a monomeric building block, facilitating the development of modified oligonucleotides. Its unique structural features enhance the properties of nucleic acids for research applications in gene expression studies and therapeutic development.
  7. Nucleoside Analog

    DMTr-2'-O-TBDMS-5-F-rU-3'-CE-phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite monomer facilitates the incorporation of modified nucleotides into oligonucleotides, enabling the study of nucleic acid structure and function. Its unique chemical properties allow researchers to explore various applications in genetics, molecular biology, and therapeutic development.
  8. Nucleoside Analog

    3'-O-Azidomethyl-ATP is a nucleoside analog that serves as a monomeric building block for nucleic acid synthesis. Its azide functional group allows for further click chemistry applications, enabling the introduction of various functionalities into nucleic acids. This reagent is essential for research in genetic engineering, synthetic biology, and the development of novel therapeutics.
  9. Nucleoside Antimetabolite/Analog

    7,9-Dimethylguanine is a nucleoside antimetabolite and analog that represents a modified nucleotide base formed during RNA degradation. It serves as a valuable biomarker for assessing the severity of alcoholic liver disease (ALD), with its levels in urine and serum providing critical insights into disease progression. This compound is pertinent in research related to metabolic disorders and liver function assessment.
  10. Nucleoside Analog

    LNA-UTP is a nucleoside analog that serves as a key building block in the synthesis of oligonucleotides. It enhances the thermal stability and specificity of nucleic acid sequences, making it invaluable for applications in molecular biology, including gene expression analysis and antisense oligonucleotide design. Its unique properties support research in areas such as RNA interference and the development of diagnostic tools.
  11. Nucleoside Analog

    DMTr-2'-O-Me-rA(Bz)-3'-(D)-DPSE-phosphoramidite is a nucleoside analog that serves as a key monomer for the synthesis of modified nucleic acids. This reagent is specifically designed to enhance the stability and efficacy of RNA oligonucleotides, making it invaluable for applications in antisense research, siRNA development, and other RNA-based therapeutics. Its unique structure contributes to the creation of oligonucleotides with improved pharmacological properties.
  12. Nucleoside Analog

    O6-Me-GTP is a nucleoside analog that serves as a critical monomer for the synthesis of nucleic acids. This compound can be incorporated into RNA and DNA, facilitating studies on nucleotide function and nucleic acid interactions. It is valuable for applications in genetic research, molecular biology, and therapeutic exploration.
  13. Nucleoside Analog

    DMT-2'-O-MOE-Tr is a nucleoside analog featuring a dimethoxytrityl (DMT) protecting group. This compound plays a crucial role in the synthesis of nucleic acids, facilitating the incorporation of modified nucleotides into oligonucleotides. Its unique structure enhances stability and solubility, making it suitable for various applications in chemical biology and genomics research.
  14. Nucleoside Analog

    3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine is a nucleoside analog that serves as a valuable monomeric substrate for nucleic acid synthesis. Its unique siloxane linkage enhances the stability and solubility of nucleotides in various biochemical applications. This compound is ideal for researchers engaged in synthetic biology, genetic engineering, and the development of RNA-based therapeutics.
  15. Nucleoside Analog

    3'-O-NH2-2'-dC is a nucleoside analog that serves as a valuable monomer for nucleic acid synthesis. This compound effectively incorporates into oligonucleotides, enabling the exploration of RNA and DNA functionalities. It is utilized in various research applications, including the study of gene expression, antisense technology, and the development of novel therapeutic strategies.
  16. Nucleoside Analog

    dATPαS (2'-Deoxyadenosine 5'-O-(1-thiotriphosphate)) is a nucleoside analog that mimics natural dATP in biochemical processes. It serves as a building block for nucleic acid synthesis, facilitating the incorporation of sulfur into RNA and DNA strands. This compound is widely used in studies involving nucleotide metabolism, gene expression, and the development of molecular probes.
  17. Nucleoside Analog

    DMTr-S-5-C-Me-2'-O-Me-rU-3'-CE-phosphoramidite is a nucleoside analog utilized in oligodeoxynucleotide synthesis. This phosphoramidite derivative facilitates the incorporation of modified uridine residues into nucleic acids, enabling enhanced stability and biochemical properties. It serves as a valuable tool in genetic research, antisense oligonucleotide development, and the exploration of RNA functionalities.
  18. Nucleoside Analog

    5'-O-DMTr-3'-NH₂-2'-O-Me-dU is a nucleoside analog designed for use in nucleic acid synthesis. This compound serves as a monomeric building block, facilitating the incorporation of modified nucleotides into oligonucleotides. Its unique structure enhances the stability and functionality of nucleic acids, making it a valuable tool in molecular biology research. Potential applications include RNA synthesis, bioconjugation, and the development of therapeutic oligonucleotides.
  19. Nucleoside Analog

    5'-O-DMTr-2'-O-TBDMS-5-Me-U-3'-CE Phosphoramidite is a modified nucleoside analog designed for RNA oligonucleotide synthesis. The presence of protecting groups enhances the stability and compatibility during the synthesis process, enabling efficient incorporation into RNA strands. This reagent is ideal for use in various applications, including the development of RNA-based therapeutics and biotechnological research involving RNA manipulation.
  20. Nucleoside Analog

    5-Hydroxy-dCTP is a nucleoside analog that serves as a substrate for DNA polymerases during nucleic acid synthesis. Its incorporation into DNA can facilitate studies of replication dynamics and mutagenesis. This reagent is invaluable in molecular biology and biochemical research applications involving DNA manipulation and analysis.
  21. Adenosine Analog

    8-Methoxyadenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits smooth muscle vasodilatory effects and possesses potential anti-cancer properties by inhibiting tumor progression. It is valuable for research applications in cardiovascular studies and cancer biology, providing insights into adenosine's role in these processes.
  22. Nucleoside Analog

    3'-O-NH2-2'-dG is a nucleoside analog that serves as a crucial monomeric raw material for nucleic acid synthesis. This compound can be utilized in the development of modified oligonucleotides and other nucleic acid-based applications, facilitating studies in gene expression, molecular biology, and therapeutics. Its unique structural modification enhances stability and functionality in various research contexts.
  23. GTP Analog

    isoGTP lithium is a guanosine triphosphate analog that serves as a substrate for various GTP-binding proteins. It is utilized in research to investigate GTPase activity and to study cellular signaling pathways that are mediated by GTP. This compound is valuable for exploring the biological roles of GTP in processes such as protein synthesis and signal transduction.
  24. Nucleoside Analog

    2'-O-MOE-5-Me-rC(Bz) is a nucleoside analog that serves as a valuable monomeric raw material for nucleic acid synthesis. This compound is characterized by its 2'-O-methoxyethyl group and 5-methyl modification, which enhance its stability and binding affinity. It is commonly utilized in the design and synthesis of nucleic acid therapeutics and probes, supporting research in gene regulation, RNA interference, and other areas of molecular biology.
  25. Nucleoside Analog

    CAP m7(3'-OMeG)(5')vppp(5')(2'-OMeA)pU is a nucleoside analog that serves as a key component in nucleic acid synthesis. This compound exhibits enhanced stability and affinity, making it suitable for applications in RNA research and therapeutic development. Its unique modifications contribute to improved enzymatic resistance, facilitating the study of RNA-based processes and the design of novel RNA therapeutics.
  26. Nucleoside Analog

    2-Amino-ATP is a nucleoside analog that serves as a building block for nucleic acid synthesis. Its incorporation into RNA and DNA can facilitate studies in molecular biology and biochemistry, particularly in understanding nucleotide metabolism and enzyme activity. This compound is valuable for researchers investigating the roles of modified nucleotides in cellular processes and biotechnology applications.
  27. Nucleoside Analog

    DMTr-S-5-C-Me-2'-F-dA(Bz)-3'-CE-phosphoramidite is a nucleoside analog that serves as a key monomer for the synthesis of nucleic acids. It incorporates fluorinated modifications and benzoyl protection, enhancing its stability and incorporating unique properties into oligonucleotides. This compound is utilized in various applications, including the development of therapeutics and research in gene editing techniques.
  28. Nucleoside Analog

    5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rU is a nucleoside analog that serves as a monomeric substrate for nucleic acid synthesis. This compound is designed to facilitate the incorporation of modified nucleotides into oligonucleotides, enhancing stability and functionality. Its applications include the development of therapeutic oligonucleotides and RNA-based research studies.
  29. Nucleoside Analog

    Rp-ATPαS is a nucleoside analog that functions as a substrate for nucleic acid synthesis. This compound is instrumental in various biochemical research applications, particularly in studying RNA and DNA processes. Its unique structural features make it a valuable tool in the investigation of enzymatic reactions and nucleic acid modifications.
  30. Nucleoside Analog

    2'-O-Me-7-deaza-rA is a nucleoside analog with a modified ribose structure, primarily utilized as a monomer in nucleic acid synthesis. This compound enhances the stability and efficacy of oligonucleotides, making it an essential component in the development of therapeutic agents and molecular probes. Its unique properties make it suitable for various applications in genetic research, including RNA structure-function studies and RNA-based technologies.
  31. Nucleoside Analog

    3'-Phospho-ATP (3'-P-ATP) is a nucleoside analog that serves as a critical substrate in nucleic acid synthesis. Its primary mechanism involves acting as a phosphorylated nucleotide precursor, facilitating the incorporation of RNA and DNA during polymerization processes. This compound is essential for research applications in molecular biology, including genetic engineering, transcription studies, and nucleic acid assay development.
  32. Nucleoside Analog

    UTPαS is a nucleoside analog that serves as a crucial monomeric substrate for nucleic acid synthesis. It is instrumental in various research applications, particularly in the study of RNA metabolism and the development of RNA-based therapeutics. UTPαS facilitates the incorporation of modified nucleotides into nucleic acids, enabling researchers to explore new avenues in molecular biology and genetic engineering.
  33. Nucleoside Analog

    3'-O-TBDMS-2'-5-Me-dC(Bz) is a nucleoside analog designed for nucleic acid synthesis. This compound serves as a monomeric building block, facilitating the incorporation of modified nucleotides into oligonucleotides. Its unique structural features allow for enhanced stability and potential for varied applications in biochemical research, particularly in studies involving DNA and RNA modulation.
  34. Nucleoside Analog

    CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG is a nucleoside analog that functions as a key building block in nucleic acid synthesis. This compound exhibits enhanced stability and binding affinity due to its modified structure, making it ideal for applications in the development of RNA therapeutics and oligonucleotide research. Its unique features enable researchers to explore various aspects of molecular biology, including gene expression and RNA processing studies.
  35. Nucleoside Analog

    AdemA-GalNAc phosphoramidite is a nucleoside analog used as a monomeric building block in nucleic acid synthesis. This reagent serves as a critical component in the construction of oligonucleotides, facilitating the incorporation of galactosamine modifications. Its applications extend to both therapeutic research and the development of nucleic acid-based assays, enhancing the functional diversity of synthesized sequences.
  36. Nucleoside Analog

    3'-NH-Tr-2',3'-ddG(iBu)-5'-CE-Phosphoramidite is a nucleoside analog designed for RNA oligonucleotide synthesis, featuring a protective group for enhanced stability. This phosphoramidite monomer facilitates the incorporation of modified nucleotides into nucleotide sequences, enabling researchers to explore RNA function and develop novel therapeutics. Applications include basic research in molecular biology, RNA structure-function studies, and the synthesis of RNA-based drugs.
  37. Nucleoside Analog

    2′-OMe-ADP is a nucleoside analog that serves as a key building block in the synthesis of oligonucleotides. This compound is critical for the study of nucleic acid modifications and is widely used in research applications involving antisense oligonucleotides, siRNA, and other RNA-based therapeutics. Its ability to confer stability and enhance binding affinity makes it valuable for developing novel genetic tools and therapeutic strategies.
  38. Nucleoside Analog

    M7G(5')ppp(5')(2'OMeA) is a nucleoside analog that serves as a monomer for the synthesis of nucleic acids. This compound is utilized in various research applications, including the study of RNA modifications and the development of novel therapeutics. Its structural properties make it an essential tool for biochemical assays and the design of nucleic acid-based molecules.
  39. Nucleoside Analog

    DMTr-2'-O-propargyl-rC(Ac)-3'-CE-Phosphoramidite is a nucleoside analog designed for use in nucleic acid synthesis. This phosphoramidite serves as a building block for the incorporation of modified ribonucleotides, facilitating the study of RNA structure and function. Its unique propargyl group offers potential for further chemical modification, enabling diverse applications in chemical biology and therapeutic research.
  40. Nucleoside Analog

    3'-O-Phthalimido-2'-dC is a nucleoside analog that plays a crucial role in nucleic acid synthesis. This compound serves as a versatile building block for the generation of oligonucleotides and other nucleic acid-related structures. It is essential for research applications in molecular biology, genetic engineering, and the development of therapeutic nucleic acids.
  41. Nucleoside Analog

    2'-F-dCTP is a nucleoside analog that serves as a key building block in nucleic acid synthesis. It is used in various applications, including the development of modified nucleic acids for therapeutic research and the study of nucleic acid interactions. Its incorporation into oligonucleotides can enhance stability and binding affinity, making it a valuable tool in molecular biology and genetic studies.
  42. Nucleoside Analog

    5'-O-TBDMS-3'-O-TBDMS-5-(Hydroxymethyl)-dC is a nucleoside analog that serves as a critical monomeric building block for nucleic acid synthesis. Its modified hydroxymethyl group enhances stability and incorporation into oligonucleotides. This reagent is particularly useful in synthetic biology and genetic engineering applications, allowing for the exploration of nucleic acid function and structure.
  43. Nucleoside Analog

    2',3'-Dideoxy-C(Bz) is a nucleoside analog that serves as a crucial monomer for synthesizing nucleic acids. This compound can effectively inhibit viral reverse transcriptase, making it valuable for research applications in antiviral drug development and molecular biology studies. Its structural modifications enhance its stability and compatibility in various synthetic procedures.
  44. Nucleoside Analog

    3'-O-Aminothymidine is a nucleoside analog that serves as a monomeric raw material for nucleic acid synthesis. Its structure allows for incorporation into oligonucleotides, aiding in the study of nucleic acid functionality and interactions. This compound is valuable in research applications aimed at elucidating mechanisms of gene expression and developing novel therapeutic strategies.
  45. Nucleoside Analog

    2'F-DMTr-A(Bz)-SA (TEA) is a nucleoside analog designed for applications in nucleic acid synthesis. This monomeric raw material facilitates the incorporation of modified nucleotides into oligonucleotides, enhancing their stability and functionality. It is particularly valuable in the development of nucleic acid therapeutics and diagnostics.
  46. Nucleoside Analog

    5'-O-DMTr-N1-Me-pseudoU is a nucleoside analog specifically designed for nucleic acid synthesis applications. This modified uridine analogue features a 5'-O-DMTr protective group and an N1-methyl substitution, enhancing its incorporation into RNA sequences. Its unique structure allows for improved stability and functionality in oligonucleotide synthesis, making it an essential reagent for researchers in molecular biology and genetic engineering.
  47. Nucleoside Analog

    Im-NMN is a nucleoside analog that serves as a critical monomer for nucleic acid synthesis. This compound is integral for the development of various oligonucleotides and can be employed in research applications focusing on genetic engineering, synthetic biology, and molecular diagnostics. Its unique structural properties make it a valuable tool for advancing studies in nucleic acid chemistry.
  48. Nucleoside Analog

    7-Deaza-GTP is a nucleoside analog that serves as a building block for nucleic acid synthesis. It acts as a substrate for polymerases, enabling its incorporation into RNA and DNA, which may alter their stability and function. This reagent is valuable in biochemical studies related to nucleic acid interactions, RNA modifications, and the development of novel therapeutics.
  49. Nucleoside Analog

    5'-O-Bz-rA(Bz) is a nucleoside analog that serves as a monomeric substrate for nucleic acid synthesis. This compound is crucial in the development of oligonucleotides and assists in the study of nucleic acid structures and functions. Its incorporation into nucleic acid constructs can facilitate research in areas such as gene expression, RNA processing, and therapeutic applications.
  50. Nucleoside Analog

    3'-NH2-ddG (3'-Amino-2',3'-dideoxyguanosine) is a nucleoside analog that serves as a key monomer for the synthesis of nucleic acids. This compound is essential for studies involving DNA and RNA modification, as well as in the development of nucleotide analogs for therapeutic applications. Its unique structural features facilitate applications in molecular biology and genetic engineering research.

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