DMTr-2'-O-Me-rA(Bz)-3'-(L)-PSM-phosphoramidite

Catalog No.: A56749
Nucleoside Analog
DMTr-2'-O-Me-rA(Bz)-3'-(L)-PSM-phosphoramidite is a nucleoside analog that serves as a key monomer for nucleic acid synthesis. Its structures enable the incorporation of modified ribonucleotides into oligonucleotides, enhancing stability and biological functionality. This reagent is essential in various applications including the development of therapeutics, molecular probes, and antisense oligonucleotides.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDMTr-2'-O-Me-rA(Bz)-3'-(L)-PSM-phosphoramidite is a nucleoside analog that serves as a key monomer for nucleic acid synthesis. Its structures enable the incorporation of modified ribonucleotides into oligonucleotides, enhancing stability and biological functionality. This reagent is essential in various applications including the development of therapeutics, molecular probes, and antisense oligonucleotides.
Product Information
Catalog NumA56749
FormulaC51H51N6O10PS
Molecular Weight971.02
CAS Number2379296-17-8
SMILESCO[C@@H]1[C@H](O[P@@]2N3[C@](CCC3)([H])[C@H](O2)CS(=O)(C4=CC=CC=C4)=O)[C@@H](COC(C(C=C5)=CC=C5OC)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O[C@H]1N8C=NC9=C(NC(C%10=CC=CC=C%10)=O)N=CN=C98
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