2'-F T Amidite (DMTr-2'-F-dT-3'-CE-phosphoramidite) serves as a nucleoside analog in oligonucleotide synthesis. Its incorporation into nucleic acid sequences enhances thermal stability and binding affinity due to the fluorine substitution at the 2' position. This reagent is critical for studies involving RNA stability, gene expression modulation, and the development of antisense oligonucleotides.
2'-F T Amidite (DMTr-2'-F-dT-3'-CE-phosphoramidite) serves as a nucleoside analog in oligonucleotide synthesis. Its incorporation into nucleic acid sequences enhances thermal stability and binding affinity due to the fluorine substitution at the 2' position. This reagent is critical for studies involving RNA stability, gene expression modulation, and the development of antisense oligonucleotides.
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