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2’-Deoxy-2’-fluoro-5-methyl-4’-thio-β-D-arabino uridine

Purine Nucleoside Analog

2’-Deoxy-2’-fluoro-5-methyl-4’-thio-β-D-arabino uridine is a purine nucleoside analog that acts as a potent inhibitor of DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting nucleic acid metabolism. It is especially useful in cancer research for exploring therapeutic strategies and understanding the molecular mechanisms underlying tumor growth.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	135123-34-1
Applications	Purine Nucleoside Analog
Formula	C₁₀H₁₃FN₂O₄S
Molecular Weight	276.28
SMILES	O[C@H]1[C@H](F)[C@H](N2C(NC(C(C)=C2)=O)=O)S[C@@H]1CO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.