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3’-Deoxy-3’-azido-isocytidine

Purine Nucleoside Analog

3’-Deoxy-3’-azido-isocytidine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, containing an azide group that is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. These properties make it valuable for various research applications in chemical biology and medicinal chemistry.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2095417-77-7
Applications	Purine Nucleoside Analog
Formula	C₉H₁₂N₆O₄
Molecular Weight	268.23
SMILES	OC[C@@H]1[C@@H](N=[N+]=[N-])[C@@H](O)[C@H](N2C(N)=NC(C=C2)=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.