Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-(5-phenylpyridin-3-yl)purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound can be utilized in investigations aimed at understanding nucleotide metabolism and developing novel therapeutic strategies for malignancies. -
Nucleoside Metabolite
Allodeoxycholic acid is a nucleoside metabolite known for its role in cellular lipid metabolism. It exhibits significant biological activity related to the modulation of bile acid synthesis and may influence metabolic pathways associated with cholesterol homeostasis. This compound is valuable for research applications studying lipid metabolism, bile acid signaling, and related metabolic disorders. -
Purine Nucleoside Analog
3′-Deoxy-3′-fluorocytidine is a purine nucleoside analog known for its antitumor activities. This compound effectively inhibits DNA synthesis and induces apoptosis, making it a valuable tool in the study of indolent lymphoid malignancies. Its ability to mimic natural nucleosides allows for versatile applications in cancer research and therapeutic development. -
Purine Nucleoside Analog
(1S)-1,4-Anhydro-1-C-(2,4-difluoro-5-methylphenyl)-D-ribitol is a purine nucleoside analog known for its broad antitumor activity against indolent lymphoid malignancies. This compound exerts its anticancer effects primarily through the inhibition of DNA synthesis and the induction of apoptosis. It serves as a valuable tool in cancer research, particularly in studies focused on lymphoid cancer therapies and the modulation of cellular proliferation pathways. -
Uridine Analog
2',5'-Bis-O-(triphenylMethyl)uridine is a uridine analog that primarily targets nucleotide metabolism. This compound exhibits potential antiepileptic properties and serves as a valuable tool for investigating anticonvulsant and anxiolytic activities. Additionally, it may contribute to the development of novel antihypertensive agents within research applications focused on these therapeutic areas. -
Purine Nucleoside Analog
N4-Benzoyl-5-methylcytidine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable in research applications focused on exploring novel therapies for cancer treatment and understanding the mechanisms of nucleoside analogs in oncological contexts. -
Purine Nucleoside Analog
2-Bromo-6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily targets indolent lymphoid malignancies through mechanisms including the inhibition of DNA synthesis and the induction of apoptosis. It is a valuable tool for researchers investigating therapies for cancer and related cellular processes. -
Purine Nucleoside Analog
2-Amino-3,7-dihydro-5-iodo-7-β-D-ribofuranosyl-4H-pyrrolo[2,3-d]pyrimidin-4-one is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is utilized in various studies aimed at understanding the molecular dynamics of tumorigenesis and therapeutic interventions. -
Purine Nucleoside Analog
3’-Deoxy-5-trifluoromethyluridine is a purine nucleoside analog that exhibits notable antitumor activity, specifically against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focusing on the development of therapeutic strategies targeting nucleoside pathways in oncology. -
Adenosine Analog
N6,N6-Dimethyl-3'-beta-C-methyl-adenosine is an adenosine analog that primarily functions as a smooth muscle vasodilator. This compound has demonstrated potential to inhibit cancer progression, making it valuable for various research applications in oncology and cardiovascular studies. Its unique structural features enable the exploration of adenosine signaling pathways and therapeutic interventions targeting vascular and tumor growth regulation. -
Purine Nucleoside Analog
5-(2-Hydroxyethyl)-2'-deoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to cell cycle arrest and the induction of apoptosis in cancer cells. This compound is valuable for research into therapeutic strategies targeting malignancies and understanding the underlying mechanisms of antitumor efficacy. -
Purine Nucleoside Analog
1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptotic pathways. Additionally, this compound serves as a versatile click chemistry reagent, thanks to its azide functionality, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This dual utility broadens its applicability in chemical biology and medicinal chemistry research. -
Thymidine Analog
5-Ethoxymethyluridine is a thymidine analog known for its ability to incorporate into replicated DNA. This compound demonstrates insertional activity, allowing it to label cells and facilitate the tracking of DNA synthesis. It is a valuable tool in molecular biology studies involving DNA replication and cellular proliferation. -
Purine Nucleoside Analog
DMTr-dH2U-amidite is a purine nucleoside analog that primarily targets DNA synthesis. Its biological activity includes the induction of apoptosis and the inhibition of cell proliferation, making it a valuable tool in cancer research. This reagent is particularly relevant for studying indolent lymphoid malignancies and exploring therapeutic strategies in oncology. -
Purine Nucleoside Analog
(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione functions as a purine nucleoside analog, demonstrating significant antitumor activity, particularly against indolent lymphoid malignancies. This compound exhibits its anticancer effects through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. It is a valuable tool for research applications aiming to investigate therapies for lymphoid cancers and related diseases. -
Purine Nucleoside Analog
5'-Azido-5'-deoxy-2'-O-(2-methoxyethyl)-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound functions as a click chemistry reagent due to its azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with entities possessing DBCO or BCN groups, making it a versatile tool for chemical biological research. -
Purine Nucleoside Analog
5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells, making it a valuable tool for cancer research. This compound is suitable for studies aimed at understanding the effects of nucleoside analogs in therapeutic applications. -
Pyrimidine Nucleoside Analog
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine functions as a pyrimidine nucleoside analog. This compound exhibits significant biological activity, including the inhibition of DNA and RNA synthesis, as well as antiviral and immunomodulatory effects. It is applicable in biochemical research and cancer studies, providing insights into nucleic acid metabolism and potential therapeutic pathways. -
Jasmonic Acid Metabolite
(+)-7-Isomethyljasmonate is a metabolite involved in the jasmonic acid synthesis pathway. It plays a critical role in plant stress responses and development by modulating plant hormonal signaling. This compound is useful for research in plant biology, particularly in studies investigating stress responses, growth regulation, and the biochemical pathways associated with jasmonic acid functions. -
Purine Nucleoside Analog
3’-Deoxy-N6,N6-dimethyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary biological actions include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is applicable in studies focused on therapeutic strategies targeting nucleoside metabolism and cell proliferation in cancer cells. -
PNP Inhibitor
Immucillin-G is a potent inhibitor of purine nucleoside phosphorylase (PNP), a key enzyme in purine metabolism. By inhibiting PNP, Immucillin-G effectively reduces urate levels, making it valuable for research into metabolic disorders, particularly hyperuricemia. Its role in modulating purine metabolism provides significant insights for studies related to gout and metabolic diseases. -
Nucleoside Metabolite
(25R)-3α,7α,12α-Trihydroxy-5β-cholestan-26-oyl-CoA is a nucleoside metabolite that plays a crucial role in cellular metabolism and biochemistry. This compound is involved in the regulation of cholesterol levels and lipid metabolism, making it significant for research in metabolic disorders and cellular signaling pathways. It is particularly useful for studies focusing on cholesterol metabolism and its impact on health and disease mechanisms. -
Purine Nucleoside Analog
5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite functions as a purine nucleoside analog. It exhibits substantial antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. This reagent is suitable for research applications focused on cancer therapeutics and the study of nucleic acid interactions in cellular processes. -
Uridine Analog
2’,3’,5’-Tri-O-acetyl-N3-methyluridine is a uridine analog designed to investigate the biological activities of uridine. This compound exhibits potential antiepileptic properties and serves as a valuable tool for exploring anticonvulsant and anxiolytic mechanisms. Additionally, it may aid in the development of novel antihypertensive agents, expanding its utility in therapeutic research. -
Pyrimidine Nucleoside Analog
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a pyrimidine nucleoside analog known for its ability to inhibit DNA and RNA synthesis. This compound exhibits significant biological activities, including antiviral properties and immunomodulation. It is valuable for research applications in cancer therapeutics and virology, providing insights into nucleic acid metabolism and cellular responses. -
Protein Modification
DiBoc-Vidarabine-Ribose(diBoc)-2-cyanoethyl-diisopropylphosphoramidite serves as a phosphoramidite reagent for the modification of proteins. This compound enables the introduction of site-specific modifications to proteins, enhancing their functional properties or stability. It is commonly utilized in biochemical research applications focusing on protein engineering and therapeutic development. -
Purine Nucleoside Analog
N4-Benzoyl-5’-O-DMTr-2’-O-(N3-trifluoroacetyl) aminopropyl cytidine is a purine nucleoside analog. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as DNA synthesis inhibition and apoptosis induction. This compound is valuable for research in cancer biology, offering insights into therapeutic strategies targeting nucleoside metabolism and DNA replication processes. -
Adenosine Analog
4’-C-Methyl-N6-methyladenosine is an adenosine analogue that primarily targets adenosine receptors. This compound exhibits significant biological activity as a vasodilator, promoting smooth muscle relaxation, and has shown potential in inhibiting cancer cell progression. It serves as a valuable tool in research applications focused on vascular biology and cancer therapeutics. -
Purine Nucleoside Analog
N1-Allylpseudouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic applications. Researchers can leverage its properties to explore therapeutic strategies for treating various malignancies. -
Purine Nucleoside Analog
5’-Azido-5’-deoxy-2’-O-(2-methoxyethyl)uridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis. This compound also serves as a click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing alkyne groups or DBCO/BCN moieties. These properties make it a valuable tool for research in chemical biology and medicinal chemistry. -
Purine Nucleoside Analog
2'-O-Hexadecanyl guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects are primarily attributed to the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutics targeting nucleoside metabolism. -
Nucleotide Derivative
7-Deazaadenosine 5'-phosphate (7-Deaza-AMP) is a nucleotide derivative that serves as a potential substrate or competitive inhibitor for enzymes interacting with 5'-adenylic acid monophosphate. By modulating intracellular signaling pathways, particularly those involving AMP, 7-Deazaadenosine 5'-phosphate can influence various cellular functions. This compound is useful in research applications exploring nucleotide metabolism and signaling events in cellular biology. -
Purine Nucleoside Analog
2-Chloro-N6-methyl-2’-deoxyadenosine is a purine nucleoside analog that demonstrates significant antitumor activity against indolent lymphoid malignancies. This compound exerts its anticancer effects primarily through the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. It serves as a valuable tool in cancer research, particularly in the study of mechanisms underlying cellular proliferation and programmed cell death. -
Purine Nucleoside Analog
5’-O-(4,4-Dimethoxytrityl)-2’-O-methyl inosine is a purine nucleoside analog that inhibits DNA synthesis and promotes apoptosis in cancer cells. It demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. This compound serves as a valuable tool in cancer research, facilitating the study of nucleoside metabolism and therapeutic mechanisms in oncological applications. -
Purine Nucleoside Analog
2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is useful in evaluating therapeutic strategies targeting specific malignancies and elucidating the underlying mechanisms of nucleoside metabolism in treated cells. -
Purine Nucleoside Analog
3-O-Benzoyl-1,2:5,6-bis(di-O-isopropylidene)-alpha-D-galactofuranose is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological efficacy is primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. This reagent is valuable for research into cancer therapeutics and the mechanisms of nucleoside analog effects in oncological studies. -
Nucleoside Analog
Rp-ATPαS tetrasodium is a nucleoside analog that serves as a critical substrate in nucleic acid synthesis. This compound is utilized for various biotechnological applications, including the study of RNA synthesis and enzymatic functions in nucleotide metabolism. Its unique properties facilitate research into biochemical pathways and nucleic acid interactions, making it a valuable tool for molecular biology studies. -
Purine Nucleoside Analog
8-Azido-2′-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it a valuable reagent for research in oncology, particularly in studies targeting indolent lymphoid malignancies. Its unique properties make it a useful tool for investigating cancer cell biology and therapeutic strategies. -
Purine Nucleoside Analog
2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancerous cells. This compound serves as a valuable reagent for research applications focused on cancer biology and therapeutic interventions in lymphoid tumors. -
Nucleoside Metabolite
2-Hydroxyhepta-2,4-dienedioate is a nucleoside metabolite that plays a significant role in various biological processes. This compound is involved in metabolic pathways relevant to nucleoside metabolism and may serve as a valuable tool for studying nucleic acid synthesis and regulation. Its unique chemical structure enables exploration of its function in cellular activities and potential therapeutic applications in nucleic acid-related research. -
Purine Nucleoside Analog
2',3',5'-Tri-O-benzoyl-2'-beta-C-methyl-6-azauridine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies aimed at understanding the therapeutic potential of nucleoside analogs in oncology. -
Purine Nucleoside Analog
3’-O-Methyl-4-deoxy uridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This reagent is valuable for research applications focused on cancer biology and therapeutic development. -
Serotonin Product
Formyl-5-hydroxykynurenamine is a metabolite derived from serotonin through the enzymatic activity of indoleamine 2,3-dioxygenase 1 (IDO1). This compound plays a crucial role in the catabolism of serotonin, influencing various biological pathways. It is utilized in research to study serotonin metabolism and its implications in neurological disorders and immune responses. -
Purine Nucleoside Analog
1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it valuable in the treatment of indolent lymphoid malignancies. Its unique structural properties enable researchers to explore therapeutic applications in cancer biology and nucleic acid metabolism. -
Linoleic Acid Metabolite
9,10-Dihydroxy-12,13-epoxyoctadecanoate is a linoleic acid metabolite that plays a crucial role in fatty acid metabolism. This compound exhibits notable biological activity, influencing various biochemical pathways associated with lipid metabolism. Its applications in research include studying inflammation, cellular signaling, and potential roles in metabolic disorders. -
Cytosolic Thymidine Kinase/Mitochondrial Enzyme Inhibitor
Ap5dT is an inhibitor of cytosolic thymidine kinase and mitochondrial enzymes, exhibiting inhibition constants (Kis) of 0.12 μM and 0.50 μM, respectively. This compound is relevant for research on acute myelocytic leukemia, facilitating investigations into thymidine metabolism and its implications in cancer biology. Its selective inhibition properties make Ap5dT a valuable tool for studying metabolic pathways involved in cellular proliferation. -
Purine Nucleoside Analog
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy guanosine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound functions as a click chemistry reagent featuring an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules. This versatility makes it suitable for various applications in chemical biology and drug discovery. -
Purine Nucleoside Analog
6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analogue that primarily targets DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA replication and the induction of apoptosis. Its unique structure allows for diverse applications in cancer research and therapeutic development. -
Adenosine Analog
N6-Isopentenyl-2’-C-methyladenosine is an adenosine analog that primarily acts as a vasodilator by influencing adenosine receptors. This compound has demonstrated potential in inhibiting cancer progression, making it valuable for research in oncology and cardiovascular studies. Its unique structure allows for diverse applications in studying nucleotide metabolism and therapeutic interventions targeting adenosine signaling pathways. -
Nucleoside Metabolite
7,8-Dihydro-7,8-dihydroxykynurenic acid is a nucleoside metabolite that plays a role in the modulation of neurotransmitter systems. This compound exhibits neuroprotective properties and is involved in the kynurenine pathway, which has implications in neurological disorders. It is utilized in research applications focused on neurobiology and neuropharmacology, particularly in studies related to neurodegeneration and psychiatric conditions.
