Fig. 1 · Structure

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(2R-cis)-5-Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl-2,4(1H,3H)-pyrimidinedione

Purine Nucleoside Analog

(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione functions as a purine nucleoside analog, demonstrating significant antitumor activity, particularly against indolent lymphoid malignancies. This compound exhibits its anticancer effects through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. It is a valuable tool for research applications aiming to investigate therapies for lymphoid cancers and related diseases.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 142189-87-5
Applications Purine Nucleoside Analog
Formula C9H10N2O5
Molecular Weight 226.19
SMILES
OC[C@@H]1C(C[C@H](C(C(N2)=O)=CNC2=O)O1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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