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1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine

Purine Nucleoside Analog

1-(3-β-Azido-2,3-dideoxy-5-O-trityl-D-threopenta-furanosyl)thymine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it valuable in the treatment of indolent lymphoid malignancies. Its unique structural properties enable researchers to explore therapeutic applications in cancer biology and nucleic acid metabolism.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	66503-47-7
Applications	Purine Nucleoside Analog
Formula	C₂₉H₂₇N₅O₄
Molecular Weight	509.56
SMILES	CC1=CN(C(NC1=O)=O)[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)[C@H](N=[N+]=[N-])C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.