Fig. 1 · Structure
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5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite
Purine Nucleoside Analog
5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite functions as a purine nucleoside analog. It exhibits substantial antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. This reagent is suitable for research applications focused on cancer therapeutics and the study of nucleic acid interactions in cellular processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 178925-48-9 |
| Applications | Purine Nucleoside Analog |
| Formula | C39H46IN4O8P |
| Molecular Weight | 856.68 |
| SMILES | O=C(N1[C@H](O2)C[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H]2COC(C3=CC=C(C=C3)OC)(C4=CC=CC=C4)C5=CC=C(C=C5)OC)NC(C(I)=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.