Fig. 1 · Structure

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N4-Benzoyl-5’-O-DMTr-2’-O-(N3-trifluoroacetyl) aminopropyl cytidine

Purine Nucleoside Analog

N4-Benzoyl-5’-O-DMTr-2’-O-(N3-trifluoroacetyl) aminopropyl cytidine is a purine nucleoside analog. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as DNA synthesis inhibition and apoptosis induction. This compound is valuable for research in cancer biology, offering insights into therapeutic strategies targeting nucleoside metabolism and DNA replication processes.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1053243-01-8
Applications Purine Nucleoside Analog
Formula C42H41F3N4O9
Molecular Weight 802.79
SMILES
O[C@H]1[C@@H](OCCCNC(C(F)(F)F)=O)[C@H](N2C=CC(NC(C3=CC=CC=C3)=O)=NC2=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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