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DMTr-dH2U-amidite

Catalog No.: A55826
Purine Nucleoside Analog
DMTr-dH2U-amidite is a purine nucleoside analog that primarily targets DNA synthesis. Its biological activity includes the induction of apoptosis and the inhibition of cell proliferation, making it a valuable tool in cancer research. This reagent is particularly relevant for studying indolent lymphoid malignancies and exploring therapeutic strategies in oncology.
DMTr-dH2U-amidite 151503-28-5 Purine Nucleoside Analog
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDMTr-dH2U-amidite is a purine nucleoside analog that primarily targets DNA synthesis. Its biological activity includes the induction of apoptosis and the inhibition of cell proliferation, making it a valuable tool in cancer research. This reagent is particularly relevant for studying indolent lymphoid malignancies and exploring therapeutic strategies in oncology.
Product Information
Catalog NumA55826
FormulaC39H47N4O7P
Molecular Weight714.79
CAS Number151503-28-5
SMILESCC(C)N(C(C)C)P(O[C@H]1C[C@H](N(C=N2)C=CC2=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)OCCC#N
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DNA Damage > Nucleoside Antimetabolite/Analog