3α,21-Dihydroxy-5α-pregnan-20-one-d3 is a deuterium-labeled derivative of the neurosteroid 3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), which acts as a positive modulator of GABAA receptors. This compound enhances the response of neurons to low concentrations of GABA, specifically at the α4β1δ subtype of GABAA receptors in vitro. It serves as a valuable stable isotope labeled reagent for research focusing on neurosteroid activity and GABAergic modulation.
3α,21-Dihydroxy-5α-pregnan-20-one-d3 is a deuterium-labeled derivative of the neurosteroid 3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), which acts as a positive modulator of GABAA receptors. This compound enhances the response of neurons to low concentrations of GABA, specifically at the α4β1δ subtype of GABAA receptors in vitro. It serves as a valuable stable isotope labeled reagent for research focusing on neurosteroid activity and GABAergic modulation.
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