α-Cyano-4-hydroxycinnamic acid-d4 is a deuterium-labeled derivative of α-Cyano-4-hydroxycinnamic acid, which acts as a non-competitive inhibitor of monocarboxylate transporters (MCTs). It effectively inhibits the mitochondrial pyruvate transporter with a Ki value of 6.3 μM. This stable isotope is widely utilized as a matrix to enhance peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications, aiding in the analysis and characterization of biomolecules.
α-Cyano-4-hydroxycinnamic acid-d4 is a deuterium-labeled derivative of α-Cyano-4-hydroxycinnamic acid, which acts as a non-competitive inhibitor of monocarboxylate transporters (MCTs). It effectively inhibits the mitochondrial pyruvate transporter with a Ki value of 6.3 μM. This stable isotope is widely utilized as a matrix to enhance peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications, aiding in the analysis and characterization of biomolecules.
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