Alpidem-d14 is a stable isotope-labeled variant of Alpidem, a potent GABAA receptor ligand targeting the α1β2γ2 subunit with an IC50 of 17 nM. This compound is primarily investigated for its anxiolytic properties and influences various biological processes, including modulation of mitochondrial permeability and glutathione levels, leading to hepatocyte necrosis. Additionally, Alpidem-d14 is utilized in research focused on anxiety disorders, convulsive conditions, and the behavioral effects in stressed rodent models.
Alpidem-d14 is a stable isotope-labeled variant of Alpidem, a potent GABAA receptor ligand targeting the α1β2γ2 subunit with an IC50 of 17 nM. This compound is primarily investigated for its anxiolytic properties and influences various biological processes, including modulation of mitochondrial permeability and glutathione levels, leading to hepatocyte necrosis. Additionally, Alpidem-d14 is utilized in research focused on anxiety disorders, convulsive conditions, and the behavioral effects in stressed rodent models.
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