SDH-IN-45

Catalog No.: A27230
BcSDH Inhibitor
SDH-IN-45 is an inhibitor of succinate dehydrogenase (BcSDH) that targets Botrytis cinerea, exhibiting an IC50 of 5.97 μg/mL. This compound impedes fungal energy metabolism through a distinct binding mode, leading to morphological disruptions, including structural collapse and shrinkage of mycelial forms. SDH-IN-45 demonstrates potent in vitro fungicidal activity against Botrytis cinerea, making it a valuable reagent for research focused on cucumber gray mold and related phytopathological studies.
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSDH-IN-45 is an inhibitor of succinate dehydrogenase (BcSDH) that targets Botrytis cinerea, exhibiting an IC50 of 5.97 μg/mL. This compound impedes fungal energy metabolism through a distinct binding mode, leading to morphological disruptions, including structural collapse and shrinkage of mycelial forms. SDH-IN-45 demonstrates potent in vitro fungicidal activity against Botrytis cinerea, making it a valuable reagent for research focused on cucumber gray mold and related phytopathological studies.
Product Information
Catalog NumA27230
FormulaC21H16F3NO3
Molecular Weight387.35
CAS Number3112883-32-3
SMILESO=C(C1=CC=CC=C1C(F)(F)F)NOCC2=CC=CC=C2OC3=CC=CC=C3
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