ST166 free acid is an inhibitor of the PhoP-DNA complex formation, exhibiting IC50 values of 18 µM and 24 µM against PhoP and MtrAC binding to DNA, respectively. This compound demonstrates significant antibacterial activity against Macrobacterium marinum, making it a valuable tool for studying bacterial infections and pathways. Its application in research contributes to the understanding of bacterial resistance mechanisms and the development of novel antibacterial strategies.
ST166 free acid is an inhibitor of the PhoP-DNA complex formation, exhibiting IC50 values of 18 µM and 24 µM against PhoP and MtrAC binding to DNA, respectively. This compound demonstrates significant antibacterial activity against Macrobacterium marinum, making it a valuable tool for studying bacterial infections and pathways. Its application in research contributes to the understanding of bacterial resistance mechanisms and the development of novel antibacterial strategies.
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