10-Decarbamoyloxy-9-dehydromitomycin B

Catalog No.: A47112
Antibacterial Agent
10-Decarbamoyloxy-9-dehydromitomycin B is a derivative of mitomycin with notable antibacterial properties. This compound exhibits significant antibacterial and antitumor activities, making it a valuable tool for research in infectious diseases and cancer treatment. Its mechanism of action involves DNA crosslinking, leading to inhibition of replication and cell division, thereby providing insights into therapeutic potential and resistance mechanisms.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description10-Decarbamoyloxy-9-dehydromitomycin B is a derivative of mitomycin with notable antibacterial properties. This compound exhibits significant antibacterial and antitumor activities, making it a valuable tool for research in infectious diseases and cancer treatment. Its mechanism of action involves DNA crosslinking, leading to inhibition of replication and cell division, thereby providing insights into therapeutic potential and resistance mechanisms.
Product Information
Catalog NumA47112
FormulaC15H16N2O4
Molecular Weight288.30
CAS Number74148-44-0
SMILESO[C@]12N(C[C@@]3([H])[C@]2([H])N3C)C4=C(C(C(OC)=C(C4=O)C)=O)C1=C
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