Metioprim is a competitive inhibitor of bacterial dihydrofolate reductase (DHFR), targeting critical pathways in bacterial folate metabolism. It exhibits potent antibacterial activity against anaerobic bacteria and demonstrates synergistic effects when combined with DDS against E. coli and various mycobacterial strains. This reagent is valuable for antibacterial research and development, particularly in studies focused on antibiotic resistance and the efficacy of combination therapies.
Metioprim is a competitive inhibitor of bacterial dihydrofolate reductase (DHFR), targeting critical pathways in bacterial folate metabolism. It exhibits potent antibacterial activity against anaerobic bacteria and demonstrates synergistic effects when combined with DDS against E. coli and various mycobacterial strains. This reagent is valuable for antibacterial research and development, particularly in studies focused on antibiotic resistance and the efficacy of combination therapies.
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