Catalog No.
Product Name
Application
Product Information
Citations
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Drug Intermediate
5-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methylbenzamide serves as an essential drug intermediate in the synthesis of diverse bioactive molecules. This compound's structural framework enables exploration in medicinal chemistry and drug development, facilitating the creation of therapeutically relevant agents. Researchers utilize this intermediate to optimize pharmacological properties and enhance biological activity across various applications. -
Biochemical Reagent
1-Pyrenedecanoic acid is a biochemical reagent primarily utilized to assess membrane fluidity. This compound intercalates into lipid bilayers, enabling the study of membrane dynamics and properties. It is valuable in research focusing on cellular membrane behavior and related physiological processes. -
Biochemical Reagent
Xanthomegnin is a yellow pigment with biochemical properties isolated from the fungus Trichophyton megnini. This compound is widely utilized in various research applications, particularly in the study of fungal metabolism and pigment biosynthesis. Its unique colorimetric characteristics make it a valuable reagent in biochemical assays and analytical studies involving enzymatic activity and compound interactions within biological systems. -
Drug Intermediate
CCT-010354 is a chemical intermediate utilized in the synthesis of PPARα/δ dual agonists. This compound plays a key role in the development of therapeutics targeting metabolic disorders and inflammatory diseases, where modulation of peroxisome proliferator-activated receptors (PPARs) is beneficial. Its application in drug development underscores its significance in pharmaceutical research. -
Biochemical Assay Reagents
1,1'-(Azodicarbonyl)-dipiperidine (ADDP) functions as a versatile reagent in biochemical assays, primarily utilized for the condensation reactions of alcohols with acidic compounds. This compound is instrumental in the synthesis of GPR120 agonists, which exhibit antidiabetic properties, as well as in the development of triple agonists targeting PPARα, PPARγ, and PPARδ. ADDP is particularly valuable for research in metabolic diseases, facilitating advancements in therapeutic discovery. -
Phosphoramidites
DMT-2'-F-6-chloro-dA phosphoramidite is a specialized phosphoramidite used for the synthesis of oligonucleotides. Its incorporation into oligonucleotide sequences allows for the introduction of fluorinated modifications, enhancing stability and specificity. This reagent is essential for chemical biology applications and the development of nucleic acid-based therapeutics. -
Drug Intermediate
2,4-Dihydroxybenzaldehyde serves as a drug intermediate with applications in the synthesis of various Schiff base compounds. This compound demonstrates notable anti-angiogenic, anti-inflammatory, and analgesic activities, attributed to its ability to inhibit the expression of iNOS and COX-2, thus reducing the production of nitric oxide and reactive oxygen species. It is widely utilized in research focused on inflammatory conditions, contributing to the understanding of mechanisms underlying these diseases. -
Biochemical Assay Reagent
Lactobionic acid calcium dihydrate is a biomimetic acid that primarily acts as a biochemical assay reagent. This compound exhibits antioxidant and antimicrobial properties, making it useful in various research applications, including food safety and functional product development. Additionally, it has demonstrated the ability to inhibit DNA repair and protein synthesis, as well as induce oxidative stress and block specific metabolic pathways against methicillin-resistant Staphylococcus aureus (MRSA). Lactobionic acid calcium dihydrate can be sourced through electrolytic methods, microbial fermentation, or biocatalytic approaches. -
Biochemical Assay Reagent
Cephalin from bovine brain is a phospholipid that serves as a key biochemical assay reagent. It plays a crucial role in the formation of autophagosome membranes by acting as a lipid anchor for the autophagy-related protein Atg8/LC3. This compound enhances autophagic flux, facilitates cell differentiation, regulates lipid droplet fusion, and influences lipid metabolism, contributing to membrane integrity and potential anti-aging effects. Its applications in research include studies on autophagy, lipid metabolism, and cellular differentiation. -
Phosphoramidite Monomer
2'-O-Me-C(Bz) Phosphoramidite is a modified phosphoramidite monomer targeting oligonucleotide synthesis. This reagent is instrumental in the production of RNA oligonucleotides, offering enhanced stability and improved biochemical properties. Its applications include the development of antiviral agents and therapeutics through the manipulation of RNA structures. -
dIPhosphoramidite
DMT-dA(PAc) Phosphoramidite is a dIPhosphoramidite that serves as an essential building block for the synthesis of DNA and RNA oligonucleotides. This reagent is specifically designed to facilitate the incorporation of deoxyadenosine into nucleic acid sequences, providing researchers with the ability to produce modified oligonucleotides for various applications, including genetic engineering, antisense therapy, and molecular diagnostics. Its protective groups ensure stable synthesis while maintaining high efficiency in coupling reactions. -
Phosphoramidite Monomer
S-cEt-U phosphoramidite is a modified phosphoramidite monomer designed for use in oligonucleotide synthesis. This reagent facilitates the incorporation of modified nucleotides into DNA or RNA sequences, expanding the versatility of synthetic oligonucleotides. Its application is critical in various fields, including gene therapy, antisense oligonucleotide development, and the creation of innovative bioconjugates. -
Phosphoramidites
DMT-2'-F-dA(bz) phosphoramidite is a phosphoramidite specifically designed for the synthesis of oligonucleotides. This compound facilitates the incorporation of 2'-fluoro-deoxyadenosine residues into nucleic acid sequences, enhancing the stability and biological activity of the resulting oligonucleotides. Its applications are significant in fields such as gene therapy, antisense oligonucleotide research, and RNA interference studies. -
Phosphoramidites
DMT-2'O-Methyl-rC(tac) Phosphoramidite is a specialized phosphoramidite utilized in the synthesis of oligonucleotides. This compound facilitates the incorporation of 2'-O-methyl modified ribonucleosides, enhancing the stability and binding affinity of RNA sequences. Its applications are significant in molecular biology for constructing RNA oligonucleotides with improved properties for research and therapeutic purposes. -
Biochemical Reagent
Cytarabine-daunorubicin, also known as CPX-351, is a liposomal formulation that synergistically combines cytarabine and daunorubicin in a 5:1 ratio. This targeted delivery system enhances the concentration of both compounds in leukemia cells while minimizing exposure to normal bone marrow cells. It is utilized in research focused on leukemia treatment and mechanisms, making it a valuable tool for investigating therapeutic strategies and drug efficacy in hematological malignancies. -
Phosphoramidite Monomer
DMT-dI Phosphoramidite is a modified phosphoramidite monomer that serves as a key building block in oligonucleotide synthesis. This compound facilitates the efficient incorporation of deoxyinosine into nucleic acid strands, enhancing the diversity of synthetic oligonucleotides. Its application is essential for various research areas, including gene synthesis, RNA interference studies, and the development of diagnostic tools. -
Cytosine Phosphoramidite
Ac-rC Phosphoramidite is a cytosine phosphoramidite utilized in the chemical synthesis of RNA oligonucleotides. It facilitates the incorporation of cytidine nucleotides into synthetic RNA strands while maintaining the structural integrity of the molecule during complex synthetic procedures through its specialized protecting groups. This reagent is essential for advances in RNA-based research and applications in genetic engineering and antiviral studies. -
Phosphoramidite Monomer
Fmoc-protected DMT-Dt PEG2 NH2 amidite is a phosphoramidite monomer designed for oligonucleotide synthesis. This compound features a protective Fmoc group and a PEG2 linker, enhancing solubility and facilitating the incorporation of amine functionalities into nucleic acids. It is ideal for applications in DNA and RNA synthesis, enabling the development of complex oligonucleotide structures for research in genomics and therapeutic applications. -
Phosphoramidites
DMT-2'-OMe-dA(bz) phosphoramidite is a versatile phosphoramidite used primarily for the synthesis of oligonucleotides. This modified nucleoside contributes to enhanced stability and solubility in synthetic applications. It is suitable for various research applications, including molecular biology, gene synthesis, and diagnostic development. -
Phosphoramidites
N4-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-3’-deoxy-3’-fluoro-beta-D-xylofuranosyl cytidine-2’-CED-phosphoramidite is a phosphoramidite utilized in the synthesis of oligonucleotides. Its structural properties enhance the incorporation of modified nucleotides, contributing to the development of oligonucleotides with improved stability and biological activity. This reagent is valuable for applications in gene modulation, nucleic acid research, and the exploration of antisense and RNA interference strategies. -
Phosphoramidites
DMT-2'-F-dA Phosphoramidite is a modified phosphoramidite that serves as a key reagent in the synthesis of oligonucleotides. Its unique structure incorporates a fluorine atom at the 2' position, enabling enhanced stability and functionality of nucleic acids. This compound is essential for researchers in the fields of molecular biology and genetic engineering, facilitating the development of tailored oligonucleotide sequences for various applications, including diagnostics and therapeutics. -
Phosphoramidites
DMT-LNA-5mA phosphoramidite is a versatile phosphoramidite used primarily for the synthesis of oligonucleotides. Its unique structure features an LNA (locked nucleic acid) modification, enhancing the binding affinity and specificity of oligonucleotide probes. This reagent is essential for applications in molecular biology, including gene expression analysis, antisense oligonucleotide development, and RNA interference studies. -
Phosphoramidites
DMT-LNA-G phosphoramidite is a phosphoramidite that facilitates the synthesis of locked nucleic acid (LNA) containing oligonucleotides. Its unique chemical structure enhances binding affinity and stability of nucleic acid probes, improving their performance in various applications such as molecular diagnostics, RNA interference, and antisense therapy. This reagent is essential for researchers focused on the development of innovative nucleic acid-based therapeutics and tools. -
Phosphoramidites
DMT-2'-O-TBDMS-G(dmf)-CE-phosphoramidite is a phosphoramidite utilized in the synthesis of oligonucleotides. This compound serves as a key building block, facilitating the incorporation of modified nucleotides during solid-phase synthesis. Its biological activity supports research applications in gene synthesis, antisense oligonucleotide development, and RNA interference studies. As a versatile reagent, it enables advancements in nucleic acid research and therapeutic applications. -
Phosphoramidites
DMT-2'-F-Cytidine Phosphoramidite is a specialized phosphoramidite compound used in the synthesis of oligonucleotides. This reagent facilitates the introduction of a 2'-fluorine modification, enhancing the stability and affinity of oligonucleotide therapeutics. Its application is crucial in studying nucleic acid interactions and developing novel antisense and RNAi strategies. -
Drug Intermediate
BC-NH2 is a chemical intermediate primarily utilized in pharmaceutical research and development. It serves as a key building block for synthesizing functional marker substrates, facilitating studies in various biological and chemical applications. This compound is essential for advancing drug discovery and development. -
Biochemical Assay Reagent
Pyrene is a polycyclic aromatic hydrocarbon (PAH) known for its strong fluorescence, emitting in the blue region of the spectrum. This property makes it an effective biochemical assay reagent for investigating molecular interactions in both solution and at surfaces. Due to its prevalence in various environmental and biological systems, pyrene serves as a valuable model compound for studying PAHs. Researchers should be aware of its potential health risks associated with long-term exposure, including carcinogenic and mutagenic effects. -
Biochemical Assay Reagent
Aniline Blue sodium is a water-soluble dye primarily utilized as a biochemical assay reagent for the detection of nucleic acids and proteins. Its unique chemical properties enable binding to specific cellular components, resulting in a colorimetric change that enhances visualization and analysis. This reagent is frequently employed in laboratory techniques such as electrophoresis and microscopy, contributing to various biological and biochemical research applications. -
Biochemical Assay Reagent
Orange G is an azo dye that serves as a biochemical assay reagent with significant utility in environmental studies. It is commonly utilized to investigate the degradation of azo dyes, particularly within textile wastewater treatment processes. The compound's stability makes it an effective model for assessing the efficiency of various treatment technologies aimed at breaking down difficult-to-degrade organic pollutants. Research applications frequently focus on methodologies for cleaving the azo bond in Orange G, employing chemical, physical, or biological approaches to mitigate textile wastewater pollution. -
Biochemical Assay Reagent
Xylenol Orange Tetrasodium Salt is a metal indicator utilized as a biochemical assay reagent. It exhibits high sensitivity for detecting metal ions in various biochemical environments, making it valuable in studies of metal ion interactions and cellular processes. This compound is often employed in assays related to environmental monitoring, clinical diagnostics, and research into metalloproteins. -
Biochemical Assay Reagent
Toluidine blue (ZnCl2) is a basic thiazine dye that serves as a valuable biochemical assay reagent. It displays a deep bluish-purple color, effectively staining nucleic acids such as DNA and RNA, along with mast cells, cartilage, and connective tissues. By targeting acidic components, including sulfated and carboxylated mucopolysaccharides, Toluidine blue (ZnCl2) is widely utilized in histology, cytology, and pathology to enhance diagnostic capabilities. This dye is typically applied to tissue sections before microscopic analysis, and can be differentiated using an acidic alcohol solution, offering a reliable staining method for various research applications. -
Biochemical Assay Reagent
Phloxine B is a biochemical assay reagent that serves as a vital tool in various life science research applications. It exhibits properties that enable its use as a biological stain and fluorescence marker. Phloxine B is particularly effective in cell viability assays, cytotoxicity testing, and histological studies, facilitating the visualization and analysis of cellular components. -
Biochemical Assay Reagent
Biebrich Scarlet is an azo dye with organosulfur functional groups, primarily used as a biochemical assay reagent. It exhibits strong staining properties, making it suitable for various applications in histology and cytology, particularly in the visualization of cellular components. Its use extends to biochemical analysis, where it can aid in the detection and quantification of proteins and nucleic acids. -
Biochemical Assay Reagent
Rhodamine 101 inner salt is a vibrant fluorescent dye primarily utilized as a biochemical assay reagent. With excitation and emission maxima at 565 nm and 595 nm, respectively, it exhibits strong fluorescence properties. This dye is particularly effective in applications such as fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy, and enzyme-linked immunosorbent assay (ELISA), enabling precise analysis and visualization in various biological studies. -
Biochemical Assay Reagent
Biotin-PEG4-amide-PEG2-C6-Cl is a biotinylated compound that functions as a biochemical assay reagent. This compound facilitates the attachment of biotin to various biomolecules, enhancing detection in assays that utilize streptavidin or avidin-based methods. It is commonly employed in studies involving protein labeling, cellular imaging, and biomolecule tracking, making it a valuable tool for researchers in the field of biochemistry and cell biology. -
Biochemical Assay Reagent
Caramel is a biochemical assay reagent primarily utilized as a biological material in various life science research applications. It serves as an organic compound that can contribute to the study of biochemical processes and the development of analytical methods. Researchers can employ Caramel in experimental setups to enhance assay sensitivity and improve reaction conditions in diverse biochemical analyses. -
Biochemical Assay Reagent
Erythrosin B sodium salt is a water-soluble synthetic azo dye primarily utilized as a biochemical assay reagent. Its bright red coloration makes it suitable for various applications, including cellular and enzymatic assays. Research has highlighted its potential in studying dye interactions and the effects of colorants on biological systems. While it is widely used, caution is advised due to associated health concerns. -
Biochemical Assay Reagent
Basic Blue 26, also known as Victoria Blue B, is a synthetic cationic dye primarily utilized as a biochemical assay reagent. This triarylmethane dye exhibits a vivid blue hue and is effective in staining nucleic acids and proteins for detection in laboratory settings. Its capacity to interact with negatively charged biomolecules makes it a useful tool for identifying specific compounds in biological samples. Due to potential health and environmental risks, proper handling and disposal should be observed when using Basic Blue 26 in research applications. -
Biochemical Assay Reagent
Acid Black 2 is a biochemical assay reagent that serves as a dye for various applications in life science research. It is primarily utilized for protein staining and quantification in biochemical assays. This compound aids in the visualization of proteins and other biological materials, allowing for enhanced analytical accuracy in experimental protocols. -
Biochemical Assay Reagent
Xylene Fast Yellow 2G is a synthetic azo dye commonly utilized as a biochemical assay reagent. This compound exhibits excellent stability and produces a vibrant yellow color, making it ideal for applications in staining and labeling in histology and microscopy. Its resistance to fading and washing enhances its utility in various experimental protocols involving natural and synthetic materials. -
Biochemical Assay Reagent
Permanent Orange is an organic pigment utilized as a biochemical assay reagent. This synthetic compound exhibits notable fade and weather resistance, making it suitable for applications requiring durability. Its vibrant orange hue offers excellent visibility in assays, facilitating accurate analysis and monitoring. Permanent Orange can be combined with various binders and solvents, enhancing its versatility in chemical research. -
Biochemical Assay Reagent
Quin II potassium, a tetrapotassium salt, serves as an essential biochemical assay reagent. It is primarily utilized for calcium ion detection in live cells due to its high-affinity binding to Ca²⁺ ions. This enables researchers to investigate cellular processes such as signal transduction and muscle contraction, making it valuable for a variety of life science applications. -
Linker-drug Intermediate
MC-Gly-Gly-Phe-Gly-NH-CH2-O-amide-Eribulin functions as a linker-drug intermediate in the synthesis of antibody-drug conjugates (ADCs). This compound facilitates the conjugation of therapeutic agents with monoclonal antibodies, enhancing targeted delivery to cancer cells. Its application is crucial for research in developing novel ADCs to improve the efficacy and safety of cancer treatments. -
Drug Intermediate
ProX1-(SS)-DOTAGA_R is a drug intermediate designed for targeted radionuclide delivery. It specifically facilitates the localization of therapeutic agents to diseases characterized by ACP3 expression. This compound is instrumental in advancing radiopharmaceutical research and developing precision medicine strategies. -
Drug Intermediate
ProX1-(SS)-DOTAGA is a drug intermediate designed for targeted delivery in therapeutic applications. This compound specifically facilitates the transport of radionuclides, enhancing localization to diseases characterized by the expression of ACP3. Its utility in targeting and delivering therapeutic agents makes it a valuable tool in the development of precision medicine strategies. -
Biochemical Assay Reagent
DOTA-Octreotide is a chelator-conjugated peptide targeting somatostatin receptors, primarily used in biochemical assays. It facilitates the research of cancer by enabling the synthesis of radionuclide-drug conjugates (RDCs) when combined with radioactive isotopes. DOTA-Octreotide is crucial for studies in tumor imaging and targeted radiotherapy applications, enhancing the understanding of receptor-targeted approaches in oncology research. -
Drug Intermediate
BG-NH2 is a versatile pharmaceutical intermediate that serves as a key building block in the synthesis of fluorescent SNAP tag substrates. This compound is particularly useful for labeling RNA in various experimental settings, facilitating molecular studies and enhancing visualization techniques in biochemical research. BG-NH2’s unique properties make it an essential reagent for applications in drug development and molecular biology. -
Biochemical Assay Reagent
Boc-Gly-Gly-NHS ester functions as a versatile biochemical assay reagent, facilitating the selective attachment of small molecules to specific amino acid residues on proteins. This compound enables the formation of stable conjugates, enhancing applications in drug discovery and diagnostic assays. Its ability to selectively modify proteins allows for the study of protein interactions and the development of targeted therapeutics. -
Linagliptin Impurity
Linagliptin methyldimer is a known impurity of Linagliptin, a potent Dipeptidyl Peptidase IV (DPP-IV) inhibitor that exhibits an IC50 of approximately 1 nM. This compound is utilized primarily in analytical studies to characterize and quantify impurities in Linagliptin formulations. Its presence and behavior are essential for understanding the purity and efficacy of DPP-IV-related therapies in diabetes research. -
Impurity of Sildenafil
Desethyl Sildenafil is an impurity of Sildenafil, primarily known as a potent phosphodiesterase type 5 (PDE5) inhibitor, with an IC50 value of 5.22 nM. It serves as an important reference standard in the analysis of Sildenafil formulations and is utilized in the investigation of PDE5 inhibition. Research applications include quality control and pharmacokinetic studies related to Sildenafil.
