Thiamet G

Catalog No.: A12895

O-GlcNAcase inhibitor

Thiamet G

Thiamet G Chemical Structure

CAS NO. 1009816-48-1

Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal-hexosaminidase.

Availability: In stock

Package Price Qty
5 mg
$55.00
10 mg
$95.00
25 mg
$200.00
50 mg
$350.00
10mM * 1mL in DMSO
$89.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Zhu WZ, .et al. O-GlcNAc Transferase Promotes Compensated Cardiac Function and Protein Kinase A O-GlcNAcylation During Early and Established Pathological Hypertrophy From Pressure Overload, J Am Heart Assoc, 2019, Jun 4;8(11):e011260 PMID: 31131693

Biological Activity

Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal-hexosaminidase.
Targets
O-GlcNAcase
21 nM(Ki)
In vitro (25°C) DMSO 50 mg/mL (201.36 mM)
Water 50 mg/mL (201.36 mM)
Ethanol 12 mg/mL (48.32 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.27 mL 201.37 mL 402.74 mL
0.5 mM 8.05 mL 40.27 mL 80.55 mL
1 mM 4.03 mL 20.14 mL 40.27 mL
5 mM 0.81 mL 4.03 mL 8.05 mL

*The above data is based on the productmolecular weight 248.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12895
Actions Inhibitor
M. Wt 248.3
Formula C9H16N2O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1009816-48-1
SMILES CCNC1=NC2C(C(C(OC2S1)CO)O)O

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Thiamet G | Thiamet G Supplier | purchase | cost | manufacturer | order | distributor | buy 1009816-48-1| 1009816-48-1 Supplier | purchase 1009816-48-1 | 1009816-48-1 cost | 1009816-48-1 manufacturer | order 1009816-48-1 | 1009816-48-1 distributor
Rewards