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$0.00 - Zhu R, .et al. Cancer-selective bioreductive chemotherapy mediated by dual hypoxia-responsive nanomedicine upon photodynamic therapy-induced hypoxia aggravation, Biomacromolecules, 2019, May 24 PMID: 31125209
Biological Activity
Tirapazamine is a bioreductive, anti-neoplastic, anti-cancer agent that is selectively toxic to cells under hypoxic conditions.
| In vitro | DMSO | 32 mg/mL (179.62 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 56.13 mL | 280.66 mL | 561.32 mL |
| 0.5 mM | 11.23 mL | 56.13 mL | 112.26 mL |
| 1 mM | 5.61 mL | 28.07 mL | 56.13 mL |
| 5 mM | 1.12 mL | 5.61 mL | 11.23 mL |
*The above data is based on the productmolecular weight 178.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12754 |
|---|---|
| CAS No. | 27314-97-2 |
| Formula | C7H6N4O2 |
| M. Wt | 178.15 |
| Solubility | DMSO |
| Purity | >98% |
| SMILES | C1=CC=C2C(=C1)N(C(=N)N=[N+]2[O-])O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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