Catalog No.
Product Name
Application
Product Information
Citations
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Cosmetic Peptide
Kitol is a cosmetic peptide primarily involved in after-sun repair formulations. It is formed from the heat-induced dimerization of vitamin A derivatives, contributing to their stability. Research applications include evaluating the heat sensitivity of vitamin A esters using microcalorimetry, thereby enhancing the understanding of the degradation processes in cosmetic formulations. -
Anti-angiogenic Peptide
Adamtsostatin 16 is an anti-angiogenic peptide comprising 17 amino acids, featuring type I thrombospondin motifs. This compound inhibits angiogenesis by interfering with endothelial cell functions, making it a valuable tool for studying vascular biology and tumor growth. Its applications include cancer research, wound healing studies, and investigations into the mechanisms of vascular development. -
Anti-angiogenic Peptide
Adamtsostatin 18 is an anti-angiogenic peptide targeting the inhibition of angiogenesis. This peptide disrupts cell migration and proliferation, making it a valuable tool for research in cancer biology and vascular development. Its mechanism of action involves interference with pathways critical for endothelial cell function, facilitating studies on tumor growth and metastasis. -
Anti-angiogenic Peptide
Adamtsostatin 4 is an anti-angiogenic peptide that inhibits angiogenesis by targeting vascular endothelial growth factor (VEGF) signaling pathways. This peptide demonstrates significant biological activity in reducing endothelial cell proliferation and migration, making it a valuable tool in cancer research and therapeutic development aimed at combating tumors. Its application extends to studies focused on angiogenesis-related diseases and the evaluation of anti-angiogenic strategies. -
Pentapeptide
Angiotensin I/II (4-8) is a pentapeptide that corresponds to the C-terminal sequence of Angiotensin II. This compound has significant implications in cardiovascular research, specifically in studies involving blood pressure regulation and the renin-angiotensin system. Its biological activity includes the modulation of vasoconstriction and electrolyte balance, making it a valuable reagent for investigating related physiological and pathological processes. -
Immunomodulatory Octapeptide
Thymoctonan is an immunomodulatory octapeptide, also known as thymic humoral factor γ2. It plays a crucial role in modulating immune responses and has applications in research related to immunotherapy and autoimmune disorders. Thymoctonan exhibits a short half-life of less than 6 minutes at 37 °C in human, rat, and mouse blood, which should be considered when designing experiments. -
pGC-B Activator
C-Type Natriuretic Peptide (1-53), derived from porcine, rat, and mouse sources, acts as a specific activator of particulate guanylate cyclase B (pGC-B), a receptor prevalent in endothelial cells, kidneys, and cardiac tissues. This peptide is known to induce significant anti-fibrotic responses in human cardiac and renal fibroblasts by promoting the synthesis of the secondary messenger cGMP. It is valuable for research focusing on cardiovascular and renal pathophysiology, offering insights into therapeutic strategies for fibrotic diseases. -
Precursor Peptide
TRH Precursor Peptide is a precursor peptide for thyrotropin-releasing hormone (TRH), functioning primarily through its role in the production of TRH in the rat brain and pituitary. The synthesis of TRH from this precursor is zinc-dependent, highlighting its significance in neuroendocrine regulation. This peptide is valuable for research in neurological studies and the assessment of thyroid function. -
Endogenous Bioactive Peptide
Salusin-α is an endogenous bioactive peptide that modulates hemodynamic responses and promotes cell proliferation. It effectively stimulates the proliferation of quiescent vascular smooth muscle cells (VSMCs) and fibroblasts, resulting in a notable decrease in blood pressure and heart rate. Although its effects are less potent than those of Salusin-β, Salusin-α holds significant potential for applications in cardiovascular disease research and therapeutic exploration. -
Neuropeptide
APGW-amide is a neuropeptide that primarily targets neuronal signaling pathways. It has been shown to control the growth of imposex structures and promote growth in Haliotis asinina. In studies, APGW-amide inhibits Achatina neurons and modulates neuronal currents affected by neuroactive compounds. Additionally, it induces a rapid increase in intracellular calcium levels in Fura-2/AM-loaded PC12 cells, making APGW-amide valuable for research focused on the nervous system. -
Activation Peptide
Enterostatin (rat) is an activation peptide of procolipase that plays a significant role in modulating fat intake. This peptide selectively reduces body fat consumption and lowers serum cholesterol levels through a cholecystokinin 1 (CCK1) receptor-dependent mechanism. It serves as a valuable tool for research on energy balance, appetite regulation, and metabolic disorders. -
Dipeptide
L-Arginyl-L-alanine is a dipeptide that serves as a vascular smooth muscle-derived relaxing factor. It enhances the levels of cyclic GMP and nitrite in denuded arterial rings, contributing to smooth muscle relaxation. This compound is of interest in research applications related to vascular biology and cardiovascular disease mechanisms. -
Neuropeptide
Prokineticin 2 Isoform 2 (human) is a neuropeptide primarily involved in the regulation of energy metabolism and thermoregulation. This compound has been shown to decrease food intake in rodent models, making it relevant for research into hyperglycemia, metabolic syndrome, and obesity. Its role in influencing metabolic pathways makes it a valuable reagent for studies focused on appetite regulation and energy balance. -
Insect Neuropeptide
Leucomyosuppressin is an insect neuropeptide that acts as an inhibitory myotropic peptide. It is known to inhibit evoked transmitter release at the mealworm neuromuscular junction, making it a valuable tool for studying neuromuscular transmission and neuropeptide signaling in insects. This compound can be utilized in research applications focused on insect physiology and neurobiology. -
Myoactive Neuropeptide
NGFFFamide is a myoactive neuropeptide identified in sea urchins. This compound is known to regulate muscle activity by binding directly to receptor proteins on muscle cells or indirectly by stimulating nerve endings to release muscle-active factors. NGFFFamide serves as a valuable tool for investigating mechanisms of muscle contraction and relaxation in various biological and pharmacological studies. -
Tetrapeptide
Antiulcer Agent 2 is a tetrapeptide comprised of aspartic acid, alanine, histidine, and lysine, known for its potential role in ulcer treatment. This compound is located at the N-terminal of human albumin, suggesting its involvement in physiological processes related to ulcer healing. Its biological activity may extend to modulating active oxygen species, making it a valuable reagent for research in gastroenterology and oxidative stress studies. -
Substrate Peptide Of Cathepsin S
Ac-KQKLR-AMC is a substrate peptide designed for the fluorescent monitoring of Cathepsin S activity. Labeled with AMC, this compound exhibits excitation and emission wavelengths of 354 nm and 442 nm, respectively. It is primarily utilized in biochemical assays to measure the enzymatic activity of Cathepsin S, providing valuable insights into its role in physiological and pathological processes. -
Phosphorylase Kinase Peptides Fragment
Phosphorylase Kinase β-Subunit Fragment (420-436) targets the β-Subunit of phosphorylase kinase, a serine/threonine-specific protein kinase. This fragment facilitates the activation of glycogen phosphorylase, regulating the release of glucose-1-phosphate from glycogen stores. It is widely used in research applications focused on glucose metabolism, enzymatic regulation, and the signaling pathways involved in energy homeostasis. -
Fluorogenic Peptide Substrate
Tos-Gly-Pro-Lys-AMC is a fluorogenic peptide substrate specifically designed for tryptase enzyme activity. This compound facilitates the detection and quantification of tryptase activity through fluorescence, making it a valuable tool in research related to protease biology and inflammation. Its application in biochemical assays allows for the exploration of tryptase's role in various physiological and pathological processes. -
Bioactive Peptide
Abz-HPGGPQ-EDDnp is a bioactive peptide designed as a selective substrate for cathepsin K, a lysosomal cysteine protease crucial for bone remodeling and resorption. This fluorescence resonance energy transfer (FRET) peptide is specifically cleaved at the Gly-Gly bond by cathepsin K, enabling precise monitoring of its activity in physiological fluids and cell lysates. The peptide demonstrates resistance to hydrolysis by other cathepsins, thereby facilitating targeted research into autoimmune diseases and osteoporosis. Abz-HPGGPQ-EDDnp is characterized by excitation/emission wavelengths of 340 nm/420 nm, making it a valuable tool for studying protease activity in cellular contexts. -
Polypeptide
Suc-Phe-Ala-Ala-Phe-pNA is a synthetic polypeptide designed as a substrate for various proteases, including the serine alkaline protease from Caldicoprobacter guelmensis (SAPCG strain D2C22T), the protease from Aeribacillus pallidus VP3 (SPVP), as well as Alcalase 2.5 L and thermolysin type X. This substrate is utilized in biochemical assays to study protease activity and kinetics, enabling researchers to investigate the mechanisms of proteolysis. Its structural composition allows for precise measurement of protease function in various experimental settings. -
Tridecapeptide
α-Factor Mating Pheromone is a tridecapeptide secreted by Saccharomyces cerevisiae α cells, targeting the Ste2p receptor. This pheromone plays a crucial role in yeast mating processes, facilitating cell signaling and attraction between α and a cells. It is widely utilized in studies of yeast biology, signal transduction, and the mechanisms of mating induction. -
Fibrinopeptide
Fibrinopeptide B, human is a 14-amino acid peptide generated at the amino-terminus of the β-chains of fibrinogen by the action of thrombin. This peptide plays a critical role in the coagulation process, serving as a marker for thrombin activity and fibrin formation. Fibrinopeptide B is utilized in various research applications, including studies on hemostasis, thrombosis, and the regulation of blood coagulation pathways. -
Thrombin Receptor Antagonist
Thrombin receptor peptide ligand is a selective antagonist of the thrombin receptor, inhibiting its activation and downstream signaling. This compound exhibits antithrombotic properties, making it suitable for research focused on thrombotic disorders and cardiovascular diseases. Its ability to modulate thrombin activity positions it as a valuable tool for studying platelet aggregation and related pathways. -
Thrombin Cleavable Peptide
Thrombin-cleavable peptide targets thrombin and is specifically designed for thrombin recognition and cleavage. Upon enzymatic cleavage, it releases thrombolytic peptides that play a crucial role in initiating thrombolysis. This reagent is valuable for research applications related to ischemic stroke and other thrombotic conditions. -
Polypeptide
Hirudin (55-65) sulfated is a polypeptide fragment that acts as a potent inhibitor of thrombin, demonstrating significant anticoagulant properties. This compound is essential for studies related to coagulation pathways and thrombin-mediated physiological processes. Its applications extend to the investigation of antithrombotic therapies and the development of pharmacological agents targeting blood coagulation disorders. -
Bioactive Peptide
TFLLRNPNDK-NH2 is a bioactive peptide that acts as a potent agonist of the protease-activated receptor 1 (PAR-1). By mimicking the tethered ligand generated by thrombin proteolytic cleavage, this peptide reversibly binds to PAR-1, modulating various cellular responses. Key biological activities include the enhancement of liquid and protein permeability, making it valuable for research applications in cardiovascular and inflammatory studies. -
Fibrin Knob Peptide
Knob A peptide GPRPFPAC is a fibrin knob peptide that interacts with the fibrinogen molecule to inhibit clot formation. This peptide exhibits enhanced anticoagulant activity, particularly when modified with polyethylene glycol (PEG). It is utilized in various research applications, including studies on thrombosis, hemostasis, and the development of anticoagulant therapies. -
Polypeptide
Acetyl-Hirudin (55-65) sulfated is a polypeptide fragment that functions as a potent inhibitor of thrombin. This compound exhibits significant anticoagulant properties, making it valuable in studies related to blood coagulation and thrombotic disorders. Acetyl-Hirudin (55-65) sulfated is utilized in various research applications, including the investigation of thrombin's role in physiological and pathological processes. -
Peptide Substrate
PS-915 dihydrochloride is a peptide substrate that specifically targets thrombin for use in colorimetric assays. This compound enables the assessment of plasma antithrombin III (ATIII) levels by undergoing enzyme hydrolysis, which results in the release of 3-carboxy-4-hydroxyaniline (CHA). The CHA then forms a complex with alkaline-pentacyanoammine ferroate, producing a distinct blue coloration, facilitating quantification in various research applications related to coagulation and thrombosis. -
Peptide Vinyl Sulfone
WRR139 is a peptide vinyl sulfone that targets N-glycanase 1 (NGLY1) and exhibits inhibitory activity against Nrf1. This compound is involved in key disease processes, including inflammation and cancer progression. WRR139 has been shown to enhance the cytotoxic effects of Carfilzomib on cancer cells, making it a valuable tool for research in cancer therapeutics and inflammation-related studies. -
TRP-2 Derived Peptide
mTRP-2 (180-188) is a peptide derived from murine tyrosinase-related protein 2 (TRP-2), specifically corresponding to the amino acid sequence of residues 180-188. This peptide serves as a key reactive epitope for recognition by anti-B16 cytotoxic T lymphocytes (CTLs). Its applications in research include the study of immune responses and the development of cancer immunotherapies, particularly in relation to melanoma. -
TRP-2 Derived Peptide
Tyrosinase-related Protein 2 (TRP-2) (181-188) is a peptide derived from tyrosinase-related protein 2, corresponding to residues 181-188. This peptide contains the primary reactive epitope recognized by anti-B16 cytotoxic T lymphocytes (CTLs) and is designed to conform to the MHC class I H2-Kb binding motif. TRP-2 (181-188) is essential for studies in immunology and cancer research, particularly in the context of melanoma and anti-tumor immune responses. -
Tyrosinase Inhibitor
Cysteine peptide is a potent tyrosinase inhibitor that exhibits skin-whitening, antioxidant, and multi-regulatory properties. By inhibiting tyrosinase activity and obstructing melanin transport, it effectively reduces UV-B-induced skin erythema and pigmentation. Additionally, cysteine peptide plays a role in skin health by scavenging reactive oxygen species (ROS), mitigating oxidative stress, and promoting pheomelanin synthesis. This compound also functions as a plant signaling factor, influencing vegetative growth, development, and responses to environmental stressors. -
Peptide
[Asp371]-Tyrosinase (369-377), human is a peptide derived from the human tyrosinase protein and is characterized as an HLA-A2.1-restricted epitope. This peptide plays a crucial role in the development of tumor-targeted vaccines aimed at eliciting specific immune responses against melanoma. It has been utilized in research applications focused on cancer immunotherapy and cellular immune response studies. -
Nonapeptide
Tyrosinase (192-200), human mouse is a nonapeptide that serves as a significant target for cytolytic T cells (CTL) via the HLA-B44 molecule. This peptide is crucial for studying immune responses in melanoma-associated cancers. Its role in T cell recognition makes it valuable for research applications focused on cancer immunotherapy and the development of targeted treatments. -
Antioxidant Peptide
Diaminopropionoyl tripeptide-33 is an antioxidant peptide that provides protection against UVA-induced DNA damage in skin cells. This bioactive compound is primarily used in cosmetic formulations to enhance skin cell resilience and promote healthier skin. Its application in research encompasses the study of skin aging and cellular defense mechanisms, making it a valuable component in the development of dermatological products. -
Bioactive Peptide
GAD65 (524-543) is a bioactive peptide derived from the glutamic acid decarboxylase 65 protein. This peptide fragment plays a crucial role in eliciting proliferative T cell responses in the non-obese diabetic (NOD) mouse model of autoimmune diabetes. It serves as a selective stimulus for the diabetogenic T cell clone BDC2.5, enhancing the susceptibility of NOD mice to type 1 diabetes when immunized with GAD65 (524-543). This reagent is valuable for research into T cell activation, autoimmune diabetes mechanisms, and potential therapeutic targets. -
Neuroprotective Peptide
Semax is a synthetic neuroprotective peptide that mimics the adrenocorticotropic hormone (ACTH) and is capable of penetrating the blood-brain barrier. This peptide exhibits notable immunomodulatory and nootropic properties, making it relevant for research into central nervous system disorders. Semax's potential applications include investigations into Alzheimer's disease and cerebral ischemia, where its neuroprotective effects may provide valuable insights. -
α-Peptide
Oligopeptide P11-4 is an α-peptide that self-assembles into β-sheet amyloids, exhibiting hydrogel characteristics at low pH. This oligopeptide demonstrates significant potential in biomimetic mineralization and enamel regeneration, making it applicable in oral care research and development. -
Abeta Degrader
β-Sheet Breaker Peptide iAβ5 is a potent degrader of amyloid-β (Aβ) oligomers, specifically targeting the β-sheet conformation responsible for its aggregation in Alzheimer's disease. This peptide effectively promotes the degradation of fibrillar amyloid deposits in vivo, thereby mitigating the neurotoxic effects associated with Aβ. Additionally, β-Sheet Breaker Peptide iAβ5 can reduce the size and quantity of amyloid plaques while decreasing the activation of IL-1β-positive microglial cells surrounding these deposits. The incorporation of a hydrophobic benzyl alcohol (HBA) tag enables visual detection under acidic conditions, facilitating quantitative analysis in relevant research applications. -
β-Amyloid Peptide Fragment
β-Amyloid (31-35) is a peptide fragment derived from the native Amyloid-β peptide, specifically representing the shortest sequence that maintains neurotoxic functionality. This compound is primarily utilized in research focused on neurodegenerative diseases, particularly Alzheimer's disease, where it aids in the investigation of amyloid plaques and their impact on neuronal health. Its bioactivity makes it a valuable tool for understanding the mechanisms underlying neurotoxicity and for evaluating therapeutic strategies. -
dipeptide
Ile-Phe is a dipeptide known for its ability to self-associate in aqueous solutions, forming a transparent thermoreversible gel through a network of fibrillar nanostructures. This self-assembly property may play a role in biological processes involving amyloid formation and other protein aggregation phenomena. It serves as a valuable tool for studying peptide interactions and the mechanics of gel formation in various biochemical applications. -
Amyloid-β Peptide
β-Amyloid (1-28) is a fragment of the amyloid-β peptide, primarily recognized for its role in metal ion binding. This peptide is significant in the formation of amyloid plaques associated with Alzheimer's disease (AD), making it a critical target for research into AD pathogenesis and potential therapeutic interventions. It is valuable for studies investigating the biochemical pathways involved in neurodegeneration and the development of amyloid-targeting strategies. -
FITC Tagged Aβ1-42 Peptide
FITC-β-Ala-Amyloid β-Protein (1-42) is a fluorescein isothiocyanate (FITC) tagged version of the Aβ1-42 peptide. This peptide is critical in the study of Alzheimer’s disease, as it is involved in the formation of amyloid plaques that are characteristic of the condition. FITC labeling enhances its detectability in various assay formats, making it suitable for studies on peptide aggregation, interaction with receptors, and screening of compounds in Alzheimer's research. -
Amyloid-β Peptide Fragment
β-Amyloid (29-40) is a peptide fragment derived from the Amyloid-β peptide, specifically encompassing amino acids 29 to 40. This fragment plays a significant role in Alzheimer's disease research, as it contributes to the understanding of amyloid plaque formation and neurodegeneration. Its biological activity includes interactions with cellular receptors and modulation of neuroinflammatory responses, making it useful for studying mechanisms of synaptic dysfunction and potential therapeutic interventions in neurodegenerative disorders. -
Aβ Peptide
β-Amyloid (1-38) is a peptide that targets the aggregation of amyloid-beta (Aβ), primarily influencing the conversion of Aβ(1-42) to β-sheet-rich structures. This compound has been shown to reverse the detrimental effects of Aβ(1-42) on long-term potentiation in acute hippocampal slices and enhance membrane conductance in primary neuronal cultures. Additionally, β-Amyloid (1-38) alleviates Aβ(1-42)-related phenotypic changes in Caenorhabditis elegans, making it a valuable tool for research into Alzheimer’s disease and related neurodegenerative processes. -
Polypeptide
(Asp37)-Amyloid β-Protein (1-42) is a G37D mutant variant of the wild-type Amyloid-beta (1-42) peptide, which plays a crucial role in Alzheimer's disease pathology. This modified polypeptide is utilized in research studies investigating protein aggregation, neurotoxicity, and the mechanisms underlying amyloid plaque formation. Its unique properties make it an important tool for examining the functional consequences of mutations within the Amyloid-beta sequence. -
Amyloid-β Peptide
β-Amyloid (15-21) is a peptide fragment derived from the Amyloid-β peptide, primarily targeting amyloid aggregation pathways. It is essential for the study of Alzheimer's disease mechanisms and the investigation of neurodegenerative processes associated with amyloid pathology. This reagent aids in elucidating the role of amyloid plaques in neuronal toxicity and offers insights into potential therapeutic interventions. -
Bioactive Peptide
[D-Ser14]-Humanin is a modified bioactive peptide targeting amyloid-β fibrillation. This D-form variant exhibits enhanced protective effects against oxidative stress and cellular death compared to its L-form counterpart, Humanin. Its potent inhibitory activity makes [D-Ser14]-Humanin a valuable tool in Alzheimer's disease research, particularly in studies focused on amyloid-related neurotoxicity and cellular resilience.
