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Endothelin-3, human, mouse, rabbit, rat

Catalog No.: A60426
vasoactive Peptide
Endothelin-3 is a 21-amino acid vasoactive peptide that targets G-protein-coupled receptors, specifically ET-RA and ET-RB. This peptide plays a critical role in regulating vascular tone and blood pressure through its potent vasoconstrictive properties. It is primarily used in research applications related to cardiovascular physiology and pathology, as well as in studies investigating the role of endothelins in various disease models across human, mouse, rabbit, and rat systems.
Endothelin-3, human, mouse, rabbit, rat 117399-93-6 vasoactive Peptide
Grouped product items
Size Price Stock Qty
500µg
$145.00
In stock
1mg
$225.00
In stock
5mg
$690.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEndothelin-3 is a 21-amino acid vasoactive peptide that targets G-protein-coupled receptors, specifically ET-RA and ET-RB. This peptide plays a critical role in regulating vascular tone and blood pressure through its potent vasoconstrictive properties. It is primarily used in research applications related to cardiovascular physiology and pathology, as well as in studies investigating the role of endothelins in various disease models across human, mouse, rabbit, and rat systems.
Product Information
Catalog NumA60426
FormulaC121H168N26O33S4
Molecular Weight2643.04
CAS Number117399-93-6
SequenceCys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp(Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
Sequence shorteningCTCFTYKDKECVYYCHLDIIW(Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
SMILESC([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC(=O)[C@H]2NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CC4=CC=C(O)C=C4)NC(=O)[C@H](C(C)C)NC(=O)[C@]5(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC6=CC=C(O)C=C6)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CC7=CC=CC=C7)NC(=O)[C@@](NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@@H](N)CSSC2)[H])(CSSC5)[H])[H])[H])=O)CC(C)C)=O)CC(O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C(O)=O)C=8C=9C(NC8)=CC=CC9
SynonymsEndothelin 3 (Rat,Human)
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