WRW4-OH

Catalog No.: A60321
Bioactive Peptide
WRW4-OH is a bioactive peptide that selectively inhibits the binding of the FPRL1 agonist WKYMVm to its corresponding receptor. FPRL1 plays a crucial role as a classical chemoattractant receptor found in phagocytic cells within the peripheral blood and brain. The modulation of FPRL1 is of significant interest in research related to inflammatory responses and neurodegenerative disorders, making WRW4-OH a valuable tool for studies in immunology and neurobiology.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionWRW4-OH is a bioactive peptide that selectively inhibits the binding of the FPRL1 agonist WKYMVm to its corresponding receptor. FPRL1 plays a crucial role as a classical chemoattractant receptor found in phagocytic cells within the peripheral blood and brain. The modulation of FPRL1 is of significant interest in research related to inflammatory responses and neurodegenerative disorders, making WRW4-OH a valuable tool for studies in immunology and neurobiology.
Product Information
Catalog NumA60321
FormulaC61H64N14O7
Molecular Weight1105.25
CAS Number722541-91-5
SequenceTrp-Arg-Trp-Trp-Trp-Trp
Sequence shorteningWRWWWW
SMILESC([C@@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(O)=O)=O)=O)NC([C@H](CC=5C=6C(NC5)=CC=CC6)NC([C@@H](NC([C@H](CC=7C=8C(NC7)=CC=CC8)N)=O)CCCNC(=N)N)=O)=O)C=9C=%10C(NC9)=CC=CC%10
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