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N-Formyl-MMYALF

Catalog No.: A60310
Mitochondrial N-formyl Peptide
N-Formyl-MMYALF is a potent mitochondrial N-formyl peptide (mtFP) that selectively targets calcium ion depletion in the endoplasmic reticulum. This compound effectively inhibits the FPR-1-mediated chemotactic response of polymorphonuclear leukocytes (PMNs) to bacterial peptides, making it valuable for research in inflammation and immune response. Its utility in investigating mitochondrial function and leukocyte signaling pathways underscores its significance in the study of cellular calcium dynamics and immune modulation.
N-Formyl-MMYALF 863418-59-1 Mitochondrial N-formyl Peptide
Grouped product items
Size Price Stock Qty
1mg
$75.00
In stock
5mg
$195.00
In stock
10mg
$295.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionN-Formyl-MMYALF is a potent mitochondrial N-formyl peptide (mtFP) that selectively targets calcium ion depletion in the endoplasmic reticulum. This compound effectively inhibits the FPR-1-mediated chemotactic response of polymorphonuclear leukocytes (PMNs) to bacterial peptides, making it valuable for research in inflammation and immune response. Its utility in investigating mitochondrial function and leukocyte signaling pathways underscores its significance in the study of cellular calcium dynamics and immune modulation.
Product Information
Catalog NumA60310
FormulaC38H54N6O9S2
Molecular Weight803.00
CAS Number863418-59-1
Sequence{N-Formyl-Met}-Met-Tyr-Ala-Leu-Phe
Sequence shortening{N-Formyl-Met}-MYALF
SMILES[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@H](CCSC)NC=O)=O)CCSC)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)CC(C)C)=O)C)=O
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