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Uroguanylin (human)

Catalog No.: A60862
Endogenous Peptide Hormone
Uroguanylin (human) is an endogenous peptide hormone that acts as a natural ligand for the Guanylyl Cyclase receptor. This compound exhibits significant anti-tumor activity, particularly in the context of metastatic colorectal cancer. Uroguanylin (human) serves as a valuable tool for research applications focused on cancer biology and the exploration of signaling pathways related to gastrointestinal tumors.
Uroguanylin (human) 154525-25-4 Endogenous Peptide Hormone
Grouped product items
Size Price Stock Qty
500µg
$315.00
In stock
1mg
$505.00
In stock
5mg
$1,290.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionUroguanylin (human) is an endogenous peptide hormone that acts as a natural ligand for the Guanylyl Cyclase receptor. This compound exhibits significant anti-tumor activity, particularly in the context of metastatic colorectal cancer. Uroguanylin (human) serves as a valuable tool for research applications focused on cancer biology and the exploration of signaling pathways related to gastrointestinal tumors.
Product Information
Catalog NumA60862
FormulaC64H102N18O26S4
Molecular Weight1667.86
CAS Number154525-25-4
SequenceAsn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu (Disulfide bridge: Cys4-Cys12,Cys7-Cys15)
Sequence shorteningNDDCELCVNVACTGCL (Disulfide bridge: Cys4-Cys12,Cys7-Cys15)
SMILESN(C([C@@H](NC([C@@H](NC([C@H](CC(N)=O)N)=O)CC(O)=O)=O)CC(O)=O)=O)[C@@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@]2(C(=O)N[C@@H]([C@H](C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)C)C(=O)N[C@@H](C)C(=O)N[C@@](CSSC1)(C(=O)N[C@@]([C@@H](C)O)(C(=O)NCC(=O)N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CSSC2)[H])[H])[H]
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