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GRPP (human)

Catalog No.: A60486
Glicentin-related Pancreatic Polypeptide
GRPP (human) is a 30 amino acid peptide derived from glucagon, targeting the Glicentin-related Pancreatic Polypeptide. It is known to induce modest increases in plasma insulin levels while decreasing plasma glucagon concentrations. GRPP (human) serves as a valuable tool for research into pancreatic function and the regulation of glucose metabolism. Its specific effects on insulin and glucagon make it pertinent for studies related to metabolic disorders.
GRPP (human) 1132745-52-8 Glicentin-related Pancreatic Polypeptide
Grouped product items
Size Price Stock Qty
500µg
$270.00
In stock
1mg
$440.00
In stock
5mg
$1,025.00
In stock
10mg
$1,470.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGRPP (human) is a 30 amino acid peptide derived from glucagon, targeting the Glicentin-related Pancreatic Polypeptide. It is known to induce modest increases in plasma insulin levels while decreasing plasma glucagon concentrations. GRPP (human) serves as a valuable tool for research into pancreatic function and the regulation of glucose metabolism. Its specific effects on insulin and glucagon make it pertinent for studies related to metabolic disorders.
Product Information
Catalog NumA60486
FormulaC136H215N41O58S
Molecular Weight3384.47
CAS Number1132745-52-8
SequenceArg-Ser-Leu-Gln-Asp-Thr-Glu-Glu-Lys-Ser-Arg-Ser-Phe-Ser-Ala-Ser-Gln-Ala-Asp-Pro-Leu-Ser-Asp-Pro-Asp-Gln-Met-Asn-Glu-Asp
Sequence shorteningRSLQDTEEKSRSFSASQADPLSDPDQMNED
SMILESC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)CCC(O)=O)=O)CC(N)=O)=O)CCSC)=O)CCC(N)=O)=O)CC(O)=O)(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CO)=O)CC(C)C)=O)CCC(N)=O)=O)CC(O)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCCCN)=O)CO)=O)CCCNC(=N)N)=O)CO)=O)=O)CO)=O)C)=O)CO)=O)CCC(N)=O)=O)C)=O)CC(O)=O)=O)CCC2)CC(C)C)=O)CO)=O)CC(O)=O)=O)CCC1
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