Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
BnO-PEG5-OH serves as a polyethylene glycol (PEG) linker for proteolysis targeting chimera (PROTAC) synthesis. This compound facilitates the formation of PROTACs by providing flexibility and enhancing solubility. It is crucial for research involving targeted protein degradation, enabling the exploration of new therapeutic avenues in various diseases. -
PROTAC Linker
Fluorescein-PEG3-amine is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTAC (proteolysis-targeting chimeras). This compound facilitates the development of bifunctional molecules that promote targeted protein degradation, enabling researchers to study protein function and regulation. Its fluorescent properties make it suitable for various imaging applications, enhancing the visualization of PROTAC activity within cellular environments. -
PROTAC Linker
Bromo-PEG3-CH2-Boc is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTAC ( proteolysis-targeting chimeras) molecules. This linker features a bromo group that facilitates conjugation to target proteins, enhancing the stability and solubility of the resulting compounds. Bromo-PEG3-CH2-Boc is essential for researchers aiming to develop novel protein degradation strategies in various biological studies. Its versatility makes it ideal for applications in drug discovery and therapeutic development within the realm of targeted protein modulation. -
PROTAC Linker
Dde Biotin-PEG4-DBCO is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling efficient conjugation. Its unique properties make it suitable for applications in cellular proteomic studies and drug discovery, highlighting its utility in targeted protein degradation research. -
PROTAC Linker
Bromo-PEG1-C2-azide is a PEG-based linker designed for the synthesis of PROTACs, targeting protein degradation pathways. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynyl compounds. Additionally, it can perform strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN entities, making it a versatile tool in chemical biology for developing protein-targeting therapeutic agents. -
PROTAC Linker
Boc-NH-PEG11-NH2 is a PEG-based linker designed for use in the development of PROTACs (Proteolysis Targeting Chimeras). It facilitates the conjugation of targeting ligands to E3 ligases, enabling the selective degradation of specific proteins. This compound is essential for researchers exploring targeted protein degradation and enhancing therapeutic strategies in various diseases. -
PROTAC Linker
Hydroxy-PEG5-C1-Boc is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features a hydroxy functional group and a Boc protecting group, facilitating conjugation between a target protein ligand and an E3 ligase recruiter. Its application in chemical biology allows for the effective modulation of protein degradation pathways, making it a valuable tool for drug discovery and development. -
PROTAC Linkers
Bromo-PEG5-bromide is a polyethylene glycol (PEG)-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound is essential for creating specific targeted therapies by enabling the recruitment of E3 ubiquitin ligases to ubiquitinate and subsequently degrade target proteins. Its unique structure enhances solubility and promotes efficient drug conjugation, making it valuable in the development of innovative therapeutic strategies in chemical biology and drug discovery. -
PROTAC Linkers
m-PEG5-NH2 is a polyethylene glycol (PEG) based linker designed for use in PROTAC (proteolysis-targeting chimera) synthesis. This compound features an amino group that facilitates the conjugation of target molecules, enhancing the specificity and efficacy of protein degradation. m-PEG5-NH2 is essential for the development of novel PROTACs in drug discovery and therapeutic applications, enabling targeted modulation of protein levels in various biological systems. -
PROTAC Linkers
m-PEG4-azide is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring an azide functional group, it is capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules. This reagent is valuable for enhancing target specificity and efficacy in pharmacological research applications. -
PROTAC Linker
Diazo Biotin-PEG3-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide functional group that enables its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing entities. Its utility in linking biomolecules makes it a valuable tool in targeted protein degradation research and other applications involving the conjugation of proteins or small molecules. -
PROTAC Linker
9-Hydroxynonanoic acid serves as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the cellular degradation of specific target proteins by linking E3 ligases to the protein of interest. Its application is crucial in chemical biology research aimed at developing targeted protein degraders for therapeutic interventions. -
PROTAC Linker
16-Bromo-1-hexadecanol serves as a PROTAC linker facilitating the development of Proteolysis Targeting Chimeras (PROTACs). Its chemical structure enables efficient conjugation to target proteins, promoting selective degradation pathways. This compound is valuable in research focused on targeted protein degradation and therapeutic innovation in cancer and other diseases. -
PROTAC Linker
3-(3-Aminopropoxy)propan-1-ol is a key PROTAC linker utilized in the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the efficient conjugation of target proteins to E3 ligases, enabling selective degradation of specific proteins within cellular systems. It plays a critical role in research applications focused on targeted protein degradation and therapeutic development. -
PROTAC Linker
2,5-Dioxopyrrolidin-1-yl 3-((tert-butoxycarbonyl)amino)propanoate serves as a key PROTAC linker, facilitating the development of targeted protein degradation constructs. This compound enables the selective recruitment of E3 ubiquitin ligases to target proteins, thereby enhancing the efficiency of PROTACs in biological research. It is instrumental in studies focused on targeted therapy, allowing researchers to explore novel approaches in drug discovery and development. -
PROTAC Linker
(1-Boc-4-piperidinyloxy)acetic acid functions as a PROTAC linker, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). It serves as a crucial component in the synthesis of these bifunctional molecules, enhancing targeted protein degradation in cellular systems. This compound is particularly valuable for research applications involving targeted therapy and protein modulation. -
PROTAC Linker
Benzyl N-(2-aminoethyl)carbamate hydrochloride functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in connecting E3 ligases to target proteins, enabling targeted degradation of specific cellular proteins. Its application in chemical biology supports research in targeted protein degradation and the exploration of novel therapeutic strategies. -
PROTAC Linker
Potassium (2-benzyloxyethyl)trifluoroborate functions as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound is integral to the development of innovative therapeutic strategies that selectively degrade target proteins through the ubiquitin-proteasome system. Its ability to enhance target specificity and efficacy makes it a valuable reagent for researchers in drug discovery and protein biology. -
PROTAC Linker
1-Bromo-4-(3-bromopropyl)benzene serves as a crucial linker in the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the development of novel targeted degradation therapies by enabling the conjugation of target proteins to E3 ubiquitin ligases. Its application is significant in research focused on elucidating cellular mechanisms and exploring therapeutic strategies for various diseases, including cancer. -
PROTAC Linker
16-Methoxy-16-oxohexadecanoic acid is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). Its chemical structure allows for efficient conjugation to target proteins, enabling selective degradation pathways. This reagent is essential for research applications focused on exploring targeted protein degradation mechanisms and developing novel therapeutics. -
PROTAC Linker
Boc-piperidin-C-COOH is a versatile PROTAC linker that facilitates the development of targeted protein degradation molecules. By serving as a bridge between an E3 ligase ligand and a protein target, it enhances the specificity and efficacy of PROTACs. This compound is essential for researchers aiming to explore protein modulation and degradation pathways in cellular studies. -
PROTAC Linker
1-Bromo-3-(3-bromopropoxy)propane is a versatile PROTAC linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the formation of bifunctional molecules that recruit E3 ligases for targeted protein degradation. Its unique structure allows for optimized interaction with specific biological targets, making it invaluable for research in drug discovery and therapeutic development. -
PROTAC Linker
3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid hydrochloride serves as a PROTAC linker, facilitating the development of heterobifunctional molecules for targeted protein degradation. This compound plays a critical role in the synthesis of PROTACs, enabling the selective modulation of protein activity within cellular pathways. Its unique structural properties make it a valuable tool in chemical biology and therapeutic research applications aimed at degrading specific proteins associated with various diseases. -
PROTAC Linkers
Thiol-PEG8-alcohol is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features a thiol group, facilitating conjugation to target proteins while enhancing solubility and stability. Its application is essential in the development of novel therapeutic agents that induce targeted degradation of specific proteins, thus enabling innovative strategies in cellular biology and drug discovery. -
PROTAC Linker
1,18-Dibromooctadecane serves as a PROTAC linker, facilitating the development of targeted protein degradation agents. Its unique structure allows for the effective conjugation of protein-targeting moieties with E3 ligase ligands, enhancing the specificity and efficacy of PROTAC compounds. This linker is instrumental in advancing research focused on proteolysis-targeting chimeras and their therapeutic applications in various diseases. -
PROTAC Linker
3-(4-Bromophenyl)propan-1-ol serves as an effective PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins by linking E3 ligases to the desired protein of interest, thereby enhancing the efficiency of targeted protein modulation in research settings. Its utility in PROTAC development supports investigations into protein interactions, degradation pathways, and therapeutic approaches in various disease models. -
PROTAC Linker
tert-Butyl 4-(piperidine-4-carbonyl)piperazine-1-carboxylate is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of targeted protein degradation strategies by linking E3 ligases to specific protein targets. Its incorporation into PROTAC constructs is essential for enhancing selectivity and efficacy in various biological research applications, including drug discovery and cancer therapeutics. -
PROTAC Linker
Pent-4-yn-1-amine hydrochloride serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is integral in the synthesis of PROTACs, which enable selective degradation of target proteins, offering innovative approaches in drug discovery and therapeutic applications. Researchers can utilize this linker to enhance the efficacy and specificity of their PROTAC-based designs. -
PROTAC Linker
5-Bromovaleronitrile serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficiency of targeted protein degradation by promoting the formation of stable complexes between E3 ligases and substrates. Its utility in chemical biology research underscores its significance in exploring novel therapeutic avenues in cancer and other diseases characterized by protein dysregulation. -
PROTAC Linker
2-Iodoethanol is a versatile PROTAC linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the formation of covalent bonds between target proteins and ubiquitin ligases, enabling targeted protein degradation. Its application in chemical biology and drug discovery makes it a valuable tool for researchers studying protein function and regulation. -
PROTAC Linker
4-(2-Bromoethyl)benzonitrile serves as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the creation of bifunctional molecules that selectively degrade target proteins, making it valuable for research in targeted protein degradation and therapeutic applications. Its availability allows for the exploration of innovative approaches to modulate protein levels in various biological systems. -
PROTAC Linker
tert-Butyl hept-6-yn-1-ylcarbamate is a PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound enables selective degradation of target proteins through the recruitment of E3 ligases, thereby modulating cellular pathways. It is valuable for research in drug discovery and the investigation of protein function in various biological contexts. -
PROTAC Linker
PEG2-Dichloride functions as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). Its unique structure enhances the conjugation efficiency between target proteins and E3 ligases, promoting targeted protein degradation. This compound is essential for researchers developing PROTACs to probe cellular functions or therapeutic applications in drug discovery. -
PROTAC Linker
Fmoc-9-Aminononanoic acid functions as a PROTAC linker, featuring a terminal Fmoc-protected amine and a carboxylic acid group. This compound is instrumental in the synthesis of PROTACs and other conjugation applications. The Fmoc group is removable under basic conditions, yielding a free amine suitable for further conjugations. Additionally, the carboxylic acid can readily engage with primary amines in the presence of coupling agents such as EDC or HATU, facilitating the formation of stable amide bonds for diverse biochemical applications. -
PROTAC Linker
tert-Butyl (cis-3-(hydroxymethyl)cyclobutyl)carbamate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in creating targeted protein degradation systems to enhance the specificity and efficacy of therapeutic agents. Its unique structure allows for effective molecular coupling, making it valuable in chemical biology research and drug discovery applications. -
PROTAC Linker
3-Aminobicyclo[1.1.1]pentane-1-carbonitrile serves as a versatile PROTAC linker, facilitating the development of targeted protein degraders. Its unique structure enhances the efficiency of PROTAC synthesis, enabling precise modulation of protein activity in cellular systems. This compound is essential for researchers focused on targeted protein degradation and therapeutic applications in oncology and other disease models. -
PROTAC Linker
tert-Butyl (3-(3-aminopropoxy)propyl)carbamate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins, advancing research in targeted protein modulation. Its application is essential in the synthesis of innovative PROTACs to explore novel therapeutic approaches in drug discovery and cellular biology. -
PROTAC Linker
Hept-6-yn-1-amine is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This reagent provides a unique alkyne functionality that enhances the coupling of the protein ligands, enabling targeted degradation of specific proteins within the cell. Its efficient linkage properties make it a valuable tool for researchers exploring targeted protein modulation and degradation pathways in pharmacological studies. -
PROTAC Linker
tert-Butyl 11-bromoundecanoate functions as a PROTAC linker, facilitating the construction of Proteolysis Targeting Chimeras (PROTACs). This compound enhances the efficiency of targeted protein degradation by enabling the conjugation of E3 ligase ligands to the target protein. It is instrumental in drug discovery and development, particularly in studies aimed at regulating protein levels for therapeutic purposes. -
PROTAC Linker
tert-Butyl N-[3-(tetramethyl-1,3,2-dioxaborolan-2-yl)propyl]carbamate functions as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of targeted protein degradation applications, contributing to advancements in therapeutic research. Its unique structural properties enable effective conjugation with target proteins, making it a valuable tool in drug discovery and development efforts. -
PROTAC Linker
tert-Butyl 4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by linking ligands to E3 ubiquitin ligases. Its application in PROTAC development supports research in targeted protein degradation, offering insights into proteostasis and therapeutic interventions. -
PROTAC Linker
1,9-Diaminononane serves as a versatile linker for PROTAC (Proteolysis Targeting Chimeras) synthesis. It facilitates the conjugation of target proteins to E3 ligases, enabling targeted protein degradation. This compound is essential in the development of novel therapeutic strategies aimed at modulating protein levels in various biological systems. -
PROTAC Linker
Tert-butyl 4-(2-bromoethyl)piperidine-1-carboxylate serves as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound enhances the development of targeted protein degradation strategies, enabling researchers to investigate cellular pathways and protein interactions. Its key biological applications include elucidating the roles of specific proteins in various disease models and advancing targeted therapeutic approaches. -
PROTAC Linker
7-Methoxy-7-oxoheptanoic acid is a biochemical linker utilized in the development of PROTAC (Proteolysis Targeting Chimera) molecules. This compound enhances the stability and effectiveness of PROTACs by facilitating the interaction between the E3 ligase and the target protein, ultimately leading to targeted degradation. It is valuable in drug discovery and therapeutic research focused on modulating protein levels in cellular systems. -
PROTAC Linker
3-(4-Iodophenyl)propanoic acid serves as a versatile PROTAC linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the design of bifunctional molecules that can selectively induce the degradation of target proteins via the ubiquitin-proteasome pathway. Its unique structural properties enable effective conjugation to various target ligands, making it a valuable tool for researchers investigating targeted protein degradation and related therapeutic strategies. -
PROTAC Linker
Methyl 2-(4-(aminomethyl)phenyl)acetate hydrochloride is a PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins, making it a valuable tool in cellular and molecular biology research. Its involvement in synthetic methodologies allows for the efficient design and optimization of targeted protein degradation strategies. -
PROTAC Linker
N-(3-Aminopropyl)-N-methylcarbamic acid tert-butyl ester serves as a PROTAC linker, facilitating the design and synthesis of targeted protein degradation (PROTAC) molecules. Its unique structure enables effective conjugation of targeting ligands, enhancing the efficiency of PROTAC applications in drug discovery and development. This compound is essential for studies aimed at understanding cellular regulation and protein turnover mechanisms. -
PROTAC Linker
Br-CO-piperazine-Boc is a versatile PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimera (PROTAC) compounds. Its unique structure enhances the ability to engage in selective protein degradation, making it an essential reagent for researchers exploring targeted protein modulation and degradation pathways. This compound is highly applicable in drug discovery and development, specifically for the development of novel therapeutic agents that can regulate protein levels in disease models. -
PROTAC Linker
4-((tert-Butyldimethylsilyl)oxy)butan-1-ol functions as a versatile PROTAC linker. It plays a critical role in the synthesis of Proteolysis Targeting Chimeras (PROTACs), enabling the targeted degradation of proteins. This compound is essential for researchers investigating protein interactions and developing novel therapeutic strategies through targeted protein modulation. -
PROTAC Linker
6-Aminohexanenitrile is a versatile PROTAC linker that facilitates the development of targeted protein degradation technologies. Its unique structure allows for effective conjugation with active targeting moieties and effector proteins, enhancing the specificity and efficacy of PROTACs. This compound is essential for researchers aiming to explore protein modulation and degradation pathways in drug discovery and therapeutic applications.
