Catalog No.
Product Name
Application
Product Information
Citations
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Endogenous Metabolite
2-Methylbenzoxazole is an endogenous metabolite involved in various biochemical pathways. This compound acts as a crucial biomarker and is utilized in studies examining metabolic processes and cellular signaling mechanisms. Its biological activity makes it significant for research applications focusing on metabolic regulation and potential therapeutic targets. -
Endogenous Metabolite
L-Arabinitol is an endogenous metabolite with potential as a biomarker for the consumption of various food products, including sweet potato, deerberry, and moth bean. It has been associated with Alzheimer's disease and ribose-5-phosphate isomerase deficiency. This compound is valuable in research investigating metabolic disorders and neurodegeneration. -
Endogenous Metabolite
Methyl anisate is an endogenous metabolite with aromatic properties. This compound plays a role in various biological processes and is utilized in research to study metabolic pathways and enzymatic activities. Its distinct chemical profile and biological significance make it valuable in metabolomics and pharmacological studies. -
Endogenous Metabolite
(Rac)-Rhododendrol, also known as (Rac)-Betuligenol, is an aromatic compound that exhibits pro-oxidant activity. Its biological significance includes potential applications in the suppression of liver diseases, although it can also induce cytotoxicity in melanocytes, leading to cell death. The metabolite RD-quinone, derived from (Rac)-Rhododendrol, is known to cause enzyme inactivation and induce endoplasmic reticulum stress through thiol protein binding. Furthermore, melanin produced from (Rac)-Rhododendrol demonstrates strong pro-oxidant properties, contributing to oxidative stress. -
Endogenous Metabolite
3,7,11,15-Tetramethyl-2-hexadecen-1-ol is an endogenous metabolite that plays a crucial role in the synthesis of vitamin E and its precursor, vitamin K1. This compound regulates gene transcription through activation of the peroxisome proliferator-activated receptor alpha (PPAR-alpha) and the retinoid X receptor (RXR), highlighting its importance in cellular signaling and metabolic processes. It is valuable for research applications focused on lipid metabolism, antioxidant activity, and gene expression regulation. -
Endogenous Metabolite
C18(Plasm) LPC, a type of plasmalogen, acts as an endogenous metabolite involved in various biological processes. This compound is recognized for its role in membrane structure and function, specifically in lipid signaling. Research applications include studying its effects on cellular metabolism and investigating its potential implications in neurodegenerative diseases and cardiovascular health. -
Endogenous Metabolite
N-Stearoyl Taurine is an endogenous metabolite that exhibits activity as a fatty acyl amide. It demonstrates the ability to activate members of the transient receptor potential (TRP) family of calcium channels, linking it to various physiological processes. This compound is primarily used in research applications related to lipidomics and neurobiology, particularly in studies investigating the role of amino-acyl endocannabinoids in the central nervous system. Its discovery in rat brain lipid profiles underscores its significance in the exploration of neuronal signaling pathways. -
Endogenous Metabolite
Palmitoleoyl ethanolamide (POEA) is an endogenous fatty amide that functions primarily as a signaling molecule through the activation of cannabinoid receptors. It has been shown to exhibit anti-inflammatory and analgesic properties, making it relevant for research in pain management and inflammatory disorders. POEA's involvement in metabolic processes also positions it as a valuable target for studies in obesity and metabolic syndrome. -
Endogenous Metabolite
Amb123203 is an antiviral compound that inhibits viral budding by interrupting the interaction between mVP40 and Nedd4 proteins. It demonstrates a significant inhibitory effect on the budding of VP40 virus-like particles (VLPs) associated with Marburg (MARV) and Ebola viruses. Targeting RNA viruses that utilize the PPxY L domain for efficient budding, Amb123203 exhibits broad-spectrum antiviral activity, making it a valuable tool for research into new antiviral therapeutics. -
Endogenous Metabolite
N-Benzylacetamide, an endogenous metabolite, plays a significant role in the plasma metabolic profile of Benznidazole. It serves as a key component for understanding metabolic pathways and can be utilized in various research applications related to drug metabolism and pharmacokinetics. The study of N-Benzylacetamide can aid in elucidating the effects of metabolic end products on biological systems. -
Endogenous Metabolite
3,5-Dimethylbenzaldehyde is an endogenous metabolite that serves as a versatile building block in organic synthesis. This compound is utilized in the development of various chemical entities and can facilitate the study of metabolic pathways. Its distinctive structural features make it an important reagent in chemical research applications, particularly in the synthesis of pharmaceuticals and fine chemicals. -
Endogenous Metabolite
Ir(p-F-ppy)3, or Tris(2-(4-fluorophenyl)pyridine)iridium, serves as a highly effective photocatalyst that enhances electron transfer processes in photochemical reactions. This compound exhibits remarkable photocatalytic activity, making it suitable for various organic syntheses, particularly in facilitating selectivity in photocatalytic pathways. Additionally, Ir(p-F-ppy)3 plays a significant role in increasing the efficiency of optoelectronic devices, such as displays and solar cells, contributing to advancements in materials science and energy applications. -
Endogenous Metabolite
Bazedoxifene N-Oxide is the oxidative metabolite of the selective estrogen receptor modulator, Bazedoxifene. It serves as a valuable tool in research focused on estrogen receptor signaling pathways and provides insights into the metabolic fate of Bazedoxifene. This compound can be utilized in studies exploring the pharmacological effects and safety profiles of SERMs, contributing to a better understanding of their therapeutic applications in various estrogen-related conditions. -
Endogenous Metabolite
3-(3-Methoxyphenyl)propionic acid is an endogenous metabolite that serves as a naturally occurring organic acid in humans. This compound is primarily involved in metabolic processes and is detected in human urine, making it a valuable marker for biological research. It is utilized in studies related to metabolism, pharmacokinetics, and the evaluation of physiological conditions. -
Endogenous Metabolite
Tetrahydro-11-deoxycortisol is an endogenous metabolite that serves as a valuable research tool for studying 11 Beta Hydroxylase Deficiency. Its presence in urine makes it a relevant biomarker for assessing adrenal steroidogenesis. This compound aids in understanding the biochemical pathways and physiological implications associated with cortisol metabolism. Researchers can utilize Tetrahydro-11-deoxycortisol to explore adrenal disorders and enhance insights into steroid hormone regulation. -
Endogenous Metabolite
SR-4995 is a selective ligand for α-β-hydrolase domain-containing 5 (ABHD5), promoting lipolysis through the activation of adipose triglyceride lipase (ATGL). By displacing ABHD5 from its inhibitory interaction with perilipin-1 (PLIN1) and perilipin-5 (PLIN5), SR-4995 enhances lipid mobilization in adipose and muscle tissues. This compound is valuable for research exploring metabolic regulation and the mechanisms of lipolysis beyond PKA-dependent signaling pathways. -
Endogenous Metabolite
Vitamin K1 2,3-epoxide is an inactive metabolite of Vitamin K1 that plays a significant role in the vitamin K epoxide cycle. This compound is converted to its active form by microsomal epoxide reductase, facilitating its critical involvement in the regulation of blood coagulation. It serves as an important research tool for studies focusing on vitamin K metabolism and its implications in hemostasis and related disorders. -
Endogenous Metabolite
(E)-3-(4-Methoxyphenyl)acrylic acid primarily targets endogenous pathways and is derived from several plant species, including Arachis hypogaea and Scrophularia buergeriana. This compound exhibits notable biological activities, including hepatoprotective, anti-amnesic, and cognition-enhancing effects, along with antihyperglycemic and neuroprotective properties. Its diverse activities make it a valuable tool for research in metabolic, neurological, and cognitive studies. -
Endogenous Metabolite
Calcium 2-hydroxy-4-(methylthio)butanoate is an endogenous metabolite that plays a critical role in various biological processes. It is involved in cellular signaling pathways and may impact metabolic regulation. This compound is suitable for research applications exploring metabolic pathways, cellular responses, and biochemical analyses related to metabolic phenomena. -
Endogenous Metabolite
L-Anserine nitrate is an endogenous metabolite that serves as a potential modulator of physiological processes. It plays a role in various metabolic pathways and has been studied for its involvement in muscle metabolism and neuroprotection. Research applications include investigating its effects on cellular functions, energy metabolism, and potential therapeutic uses in disorders related to oxidative stress and inflammation. -
Endogenous Metabolite
Orotic acid hydrate is an endogenous metabolite primarily involved in the pyrimidine biosynthesis pathway. It plays a crucial role in nucleotide metabolism and cellular proliferation. Research applications of orotic acid hydrate include studies on metabolic disorders, gene expression regulation, and cellular signaling pathways. -
Endogenous Metabolite
Porphobilinogen is an endogenous metabolite involved in heme biosynthesis, functioning primarily as a precursor in the production of porphyrins. Its biological activity includes potential roles as a phototoxin and neurotoxin, making it relevant for research in photobiology and neurobiology. This compound is essential for studying metabolic pathways linked to porphyrin disorders and offers insights into the biochemical mechanisms of heme-related diseases. -
Endogenous Metabolite
3,3-Dimethylglutaric acid is an endogenous metabolite that plays a role in metabolic pathways associated with branched-chain fatty acids. It is occasionally detected in human urine and serves as a useful ligand for the synthesis of metal complexes. Its applications are relevant in biochemical research focused on metabolism and the exploration of metal-ligand interactions. -
Endogenous Metabolite
3-Hydroxy-4-aminopyridine is an endogenous metabolite that plays a significant role in cellular metabolism. This compound is primarily involved in the modulation of neurotransmitter release and has implications in studying neurological disorders. Its biological activity makes it valuable in research focused on neuronal signaling pathways and the exploration of potential therapeutic targets in neuropharmacology. -
Endogenous Metabolite
Coproporphyrin I is an endogenous metabolite primarily found in urine and blood. It serves as an important biomarker in the study of liver diseases and various forms of porphyria. This compound aids in understanding metabolic dysfunctions and can provide insights into the pathophysiology of related disorders. -
Endogenous Metabolite
4-Methylbiphenyl is an endogenous metabolite involved in various biochemical pathways. This compound serves as a key reference standard in metabolic studies and is utilized to investigate metabolic profiles in biological samples. Its role in research enhances the understanding of metabolic enzyme activities and the effects of metabolites in physiological contexts. -
Endogenous Metabolite
D-Lyxose is an endogenous metabolite and a rare pentose sugar that serves as an important precursor in pharmaceutical synthesis. It is utilized in the development of antitumor agents, including α-galactosylceramide-based immunostimulants, and acts as a starting material for L-nucleoside analogs in antiviral drug research. Additionally, D-Lyxose can function as a synthetic intermediate for the production of other rare sugars, such as L-ribose, making it a versatile reagent in biochemical and medicinal applications. -
Endogenous Metabolite
2-Acetyl-3-ethylpyrazine is an endogenous metabolite known for its role in various biological processes. It participates in the modulation of neurotransmitter activity and exhibits potential influence on sensory perception. This compound is utilized in research concerning metabolic pathways and flavor compound synthesis. Its unique properties make it a valuable tool for studies in biochemistry and sensory biology. -
Endogenous Metabolite
Dichloroiodomethane is an endogenous metabolite that plays a significant role in various biochemical processes. It has been investigated for its potential applications in metabolic studies and toxicity assessments. Research into dichloroiodomethane may provide insights into human metabolism and the physiological impacts of halogenated compounds. -
Endogenous Metabolite
Ganoderic acid D2 is a triterpenoid derived from Ganoderma lucidum, known for its diverse biological activities. This compound exhibits significant anticancer, anti-inflammatory, and antioxidative effects, making it a valuable tool in research related to cancer biology and oxidative stress. Its role as an endogenous metabolite further enhances its relevance in pharmacological studies and natural product research. -
Endogenous Metabolite
L-Gulono-1,4-lactone is a substrate for L-gulono-1,4-lactone oxidoreductase, facilitating the final step in the biosynthesis of L-ascorbic acid (vitamin C). As a direct precursor of vitamin C, it plays a crucial role in the metabolic pathways of animals, plants, and certain protists. This compound is essential for research in metabolic regulation, antioxidant activity, and the physiological roles of vitamin C in various biological systems. -
Endogenous Metabolite
Glycocholic acid hydrate is an endogenous metabolite that plays a crucial role in bile acid synthesis and fat emulsification. It is involved in intestinal absorption processes and influences cholesterol metabolism. This compound is utilized in research related to digestion, bile acid signaling, and metabolic disorders, providing insights into gastrointestinal health and disease mechanisms. -
Endogenous Metabolite
2-Methoxybenzoic acid serves as an internal standard for salicylic acid and its proposed biosynthetic precursors, particularly in studies involving cucumber leaves. This compound is also utilized in the synthesis of Benextramine, highlighting its role in various research applications related to plant physiology and organic synthesis. -
Endogenous Metabolite
Isethionic acid sodium salt is an endogenous metabolite that plays a key role in cellular osmoregulation. This compound has been implicated in various physiological processes, including amino acid metabolism and oxidative stress response. It serves as an important tool for research applications focused on human metabolism and the study of ionic balance in biological systems. -
Endogenous Metabolite
3-(3,4,5-Trimethoxyphenyl)propanoic acid is an endogenous metabolite derived from various herbs and spices, notably Piper longum and Piper retrofractum. This compound exhibits potential biological activity and serves as a valuable tool for research into natural product chemistry and the study of metabolic pathways. Its presence in traditional herbal medicine highlights its significance in investigations related to phytochemistry and pharmacology. -
Endogenous Metabolite
Mesoxalate sodium (monohydrate) is an endogenous metabolite that plays a role in various metabolic pathways. Its primary mechanism is influencing the metabolism of oxalate and related compounds. Mesoxalate is utilized in research focused on metabolic disorders and renal function, providing insights into oxalate homeostasis and its implications in health and disease. -
Endogenous Metabolite
CL-385319 is an N-substituted piperidine compound that targets the H5N1 avian influenza A virus, demonstrating inhibitory activity against infection. It exhibits an IC50 of 27.03±2.54 μM in Madin-Darby canine kidney cells (MDCK) and displays low cytotoxicity with a CC50 of 1.48 mM. CL-385319 effectively inhibits the entry of pseudoviruses carrying various H5N1 strains, although no effect is observed on VSV-G pseudotyped particles. Notably, mutations M24A in HA1 and F110S in HA2 confer resistance to CL-385319, suggesting the significance of these residues for binding efficacy. This compound is suitable for research applications concerning influenza virus entry mechanisms and antiviral drug development. -
Endogenous Metabolite
4,4-Dimethoxy-2-butanone is identified as an endogenous metabolite involved in various biochemical pathways. This compound has potential implications in research focused on metabolic processes and the study of metabolic disorders. Its role as a metabolite makes it valuable for investigations into the physiological effects of metabolites and their impact on cellular functions. -
Endogenous Metabolite
Ethoxyacetic acid is an endogenous metabolite involved in metabolic pathways. It plays a role in various biochemical processes, influencing cellular functions and responses. This compound is utilized in research to study metabolic reactions and the impact of metabolites on cellular dynamics. Its significance in understanding metabolic regulation makes it a valuable tool for investigators in the fields of biochemistry and molecular biology. -
Endogenous Metabolite
H-HomoArg-OH.HCl is an endogenous metabolite primarily involved in the urea cycle and nitric oxide synthesis. This compound plays a significant role in various physiological processes, including the regulation of cardiovascular function and modulation of cellular signaling pathways. It is commonly used in biochemical research to study metabolic pathways and analyze nitrogen metabolism in biological systems. -
Endogenous Metabolite
AalphaC (AαC) is an endogenous metabolite recognized as a potential carcinogen, primarily arising from tobacco smoke exposure. It serves as a crucial biomarker in monitoring tobacco-related health risks, as urinary concentrations of AalphaC are significantly elevated in smokers compared to non-smokers. Additionally, AalphaC levels correlate with serum nicotine concentrations, reinforcing its relevance in tobacco research. Furthermore, dietary factors, such as high-temperature cooked beef, can influence AalphaC urinary levels, while vegetable consumption is associated with reduced levels. AalphaC's distinct biological activity makes it an essential compound for studying tobacco exposure and its health implications. -
Endogenous Metabolite
D-Citrulline is an endogenous metabolite that serves as a precursor in the biosynthesis of nitric oxide. It has been shown to significantly mitigate polymorphonuclear leukocyte (PMN)-induced cardiac contractile dysfunction in isolated perfused rat hearts subjected to ischemia/reperfusion, operating through a non-nitric oxide-mediated mechanism. This compound is valuable for research applications related to cardiovascular physiology and inflammatory responses. -
Endogenous Metabolite
4-Hydroxycyclohexanecarboxylic acid is an endogenous metabolite that plays a role in various biochemical pathways. This compound is recognized for its potential involvement in metabolic processes and can serve as a useful tool for studying metabolic disorders and cyclohexanol derivatives. Its unique structure offers opportunities for exploring the physiological effects and functions of cyclohexyl compounds in biological systems. -
Endogenous Metabolite
16-Doxylstearic acid (16-DSA) is a radical spin label derivative of stearic acid that incorporates a 4,4-dimethyl-3-oxazolidinyloxy group. This compound serves as a valuable tool for studying the biophysical properties of cellular membranes and the dynamics of hydrophobic proteins. Its unique structure allows for electron paramagnetic resonance (EPR) applications, facilitating insights into molecular interactions and membrane organization in biological research. -
Endogenous Metabolite
Cholesteryl Linolenate is an endogenous metabolite that plays a critical role in lipid metabolism. This compound can serve as a key component in studies involving cell membrane dynamics and signaling pathways related to lipid metabolism. Its biological activity makes it valuable for research in metabolic disorders and the effects of lipids on cellular functions. -
Endogenous Metabolite
Butyric acid-13C4 sodium is a stable isotope-labeled compound targeting endogenous metabolites. It plays a crucial role in promoting cell proliferation and regulating gene expression. This reagent is essential for metabolic research and compound development, aiding scientists in elucidating the functions of short-chain fatty acids in biological systems. Additionally, it contributes to studies in nutrition and intestinal health by investigating its impact on probiotic function and the modulation of the intestinal microbiota. -
Endogenous Metabolite
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride is an endogenous metabolite that functions as an inhibitor of glycogen phosphorylase and α-glucosidases. This naturally occurring pyrrolidine alkaloid, isolated from Arachniodes standishii and Angylocalyx boutiqueanus, plays a critical role in carbohydrate metabolism. Its unique inhibitory properties make it valuable for research applications in studying metabolic disorders and enzyme regulation. -
Endogenous Metabolite
Isopentenyl pyrophosphate trilithium serves as a key intermediate in the biosynthesis of terpenes, functioning as an essential building block in isoprenoid pathways. Its role in cellular metabolism highlights its importance in various biological processes, including growth and development in plants and microorganisms. This compound is valuable for research on metabolic engineering, terpene production, and investigating the biochemical pathways related to isoprenoids. -
Endogenous Metabolite
Nonanoylcarnitine is an endogenous metabolite linked to chronic exposure to polycyclic aromatic hydrocarbons (PAHs). It has been identified as a potential biomarker for assessing metabolic outcomes related to PAH exposure and may provide insights into the prognosis of acute myocardial infarction. This compound serves as a valuable tool in research focused on environmental toxicology and cardiovascular health. -
Endogenous Metabolite
12-Doxylstearic acid is a derivative of stearic acid featuring a hydrophobic spin label provided by the 4,4-dimethyl-3-oxazolinyloxy (DOXYL) group. This compound is primarily employed to investigate the molecular properties of membranes and hydrophobic proteins. Its ability to function as a spin label makes it valuable for applications in electron paramagnetic resonance (EPR) spectroscopy, enabling researchers to analyze lipid dynamics and protein conformational changes within biological systems.
