Catalog No.
Product Name
Application
Product Information
Citations
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Endogenous Metabolite
(rac./meso)-Astaxanthin is a carotenoid pigment that functions as a lipid-soluble antioxidant, effectively scavenging free radicals. Found predominantly in marine organisms such as shrimp and salmon, it is an important endogenous metabolite with potential applications in research related to oxidative stress and cellular protection. Studies have demonstrated its bioactive properties, making it relevant for investigations into its role in health and disease prevention. -
Endogenous Metabolite
1,10-Diiododecane, a potent crosslinking reagent, is primarily recognized for its ability to facilitate the synthesis of tetrabutylammonium polygalacturonic acid. This compound also functions as an alkylating agent in the production of both symmetrical and unsymmetrical bis-cryptophanes. Furthermore, 1,10-Diiododecane can be employed in the synthesis of decane under controlled conditions at 20°C, making it a valuable tool in chemical research and organic synthesis applications. -
Endogenous Metabolite
9(S)-HpODE is an endogenous metabolite generated through the action of arachidonate 5-lipoxygenase on linoleic acid. This hydroperoxide can undergo further metabolism by potato hydroperoxide dehydratase, leading to the formation of colneleic acid. As a significant bioactive lipid, 9(S)-HpODE is important in studies related to inflammation and lipid signaling pathways. Its characterization is essential for understanding the role of lipid peroxidation in various biological processes and diseases. -
Endogenous Metabolite
1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) is an endogenous metabolite that serves as a lipid membrane precursor. This compound plays a significant role in cellular membrane biosynthesis and is particularly relevant in the study of non-alcoholic fatty liver disease. Researchers can utilize 1-P-GPA to investigate lipid metabolism and its implications in various metabolic disorders. -
Endogenous Metabolite
2-Naphthalenemethanol is an endogenous metabolite derived from the environmental contaminant 2-methylnaphthalene. This compound has been shown to covalently bind to alveolar proteins, contributing to pulmonary toxicity. It serves as a valuable tool in studies of environmental pollutants and their effects on respiratory health. Researchers may utilize 2-naphthalenemethanol to explore mechanisms of toxicity and assess the biological impact of naphthalene derivatives. -
Endogenous Metabolite
(R)-1-PeCSO, or trans-(+)-S-1-Propenyl-L-cysteine sulfoxide, functions as an endogenous metabolite. This compound is recognized as the primary flavor precursor in onions, contributing significantly to their characteristic taste and aroma. Its significance extends to studies in flavor biochemistry and plant metabolism, making it a valuable tool for research in food science and agricultural biotechnology. -
Endogenous Metabolite
6-Methylnicotinamide is a nicotinamide derivative that functions as an endogenous metabolite. In research settings, it has been observed to exacerbate neurological damage during the acute phases of intracerebral hemorrhage in rat models. Additionally, 6-Methylnicotinamide enhances the coordination interactions between acylamino groups and defective Pb2+ cations, contributing to significant improvements in the efficiency of perovskite solar cells, achieving up to 24.33% efficiency while maintaining excellent stability under environmental stressors such as heat and light. -
Endogenous Metabolite
3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite that serves as a precursor to chenodeoxycholic acid. As a bile acid, it is involved in lipid digestion and absorption. This compound is useful for research applications related to bile acid metabolism, gastrointestinal health, and lipid biochemistry. -
Endogenous Metabolite
2-Amino-5-phenylpyridine is an endogenous metabolite resulting from the pyrolysis of phenylalanine within proteins. This mutagenic heterocyclic aromatic amine has been identified in broiled sardines and is associated with potential carcinogenic properties. It serves as an important compound for research into the mechanisms of mutagenesis and the study of dietary carcinogens. -
Endogenous Metabolite
Enterostatin (human, mouse, rat) is an endogenous pentapeptide that plays a critical role in the regulation of fat intake. By influencing appetite control, it modulates food consumption and energy balance. This peptide is valuable for research applications focusing on obesity, metabolic disorders, and neuroendocrine signaling pathways. -
Endogenous Metabolite
Ginsenoside Ra3 is an endogenous metabolite derived from Panax ginseng, exhibiting potential anti-cancer activity through modulation of cell signaling pathways. This compound has been studied for its ability to inhibit tumor growth and induce apoptosis in various cancer cell lines. Ginsenoside Ra3 may serve as a valuable tool in cancer research and therapeutic development. -
Endogenous Metabolite
N-Acetyl-DL-methionine is an endogenous metabolite that plays a critical role in the metabolism of sulfur-containing amino acids. It is involved in various physiological processes, including protein synthesis and methylation reactions. This compound is valuable for research in metabolic studies, as well as investigating its potential effects on cellular functions and oxidative stress. -
Endogenous Metabolite
Cholesteryl eicosapentaenoate is an endogenous metabolite that serves as a bioactive lipid mediator. It plays a crucial role in lipid metabolism and influences various signaling pathways in cellular processes. This compound is frequently used in research applications focused on inflammation, cardiovascular health, and neurobiology, providing insights into the biological mechanisms influenced by omega-3 fatty acids. -
Endogenous Metabolite
Aspartic acid calcium (Calcium L-aspartate) is a chelated compound formed from calcium and L-Aspartic acid. It is notable for its ability to penetrate the blood-brain barrier, making it useful in neurological research. Aspartic acid calcium is often employed in the preparation of prodrugs aimed at colon and cecal tissues, as well as in studies investigating inflammatory conditions. -
Endogenous Metabolite
23,25-Dihydroxy-24-oxovitamin D3 is an endogenous metabolite derived from 24(R),25-Dihydroxyvitamin D3. This compound is significant in the study of vitamin D metabolism and plays a critical role in understanding metabolic diseases. It serves as a valuable research tool for elucidating the biological functions and pathways associated with vitamin D-related disorders. -
Endogenous Metabolite
3-Deoxy-galactosone is a 1,2-dicarbonyl compound that arises from the metabolic degradation of galactose. It is notable for its formation during Maillard and caramelization reactions in food. This endogenous metabolite may serve as a useful marker for studying food chemistry and the effects of glycation on biological systems. Its involvement in various metabolic pathways makes it relevant for research in nutrition and metabolic disorders. -
Endogenous Metabolite
N-methyl-N-dithiocarboxyglucamine sodium is an endogenous metabolite known for its ability to mobilize and facilitate the excretion of metallothionein-bound cadmium (109Cd) in mouse models. This compound effectively reduces cadmium accumulation in the liver and kidneys, which are particularly vulnerable to cadmium-induced toxicity. It serves as a valuable tool for studying heavy metal detoxification processes and evaluating novel therapeutic approaches to mitigate heavy metal toxicity in biological systems. -
Endogenous Metabolite
neo-Inositol is a stereoisomer of inositol that functions as an endogenous metabolite. It is involved in various cellular signaling pathways and can influence insulin sensitivity and neuronal function. Due to its role in metabolic processes, neo-Inositol is a useful reagent for studying metabolic disorders and neurobiological research applications. -
Endogenous Metabolite
Calycanthine is an alkaloid primarily derived from the Calycanthaceae family, with notable presence in the Psychotria genus. This compound exhibits neurotoxic properties, leading to convulsions in biological systems. Its unique mechanism of action makes it a useful tool in research focused on neuropharmacology and the investigation of central nervous system effects. -
Endogenous Metabolite
1-(2-Amino-3-hydroxyphenyl)ethanone is an endogenous metabolite derived from kynurenine, primarily involved in tryptophan metabolism. This compound has been linked to various biological conditions, including bladder cancer, leukemia, and anemia. It serves as a valuable research tool for studying metabolic disturbances and their implications in these diseases. -
Endogenous Metabolite
RBM14C12 is an endogenous metabolite involved in cell signal transduction. This compound plays a critical role in studying lipid metabolism and the structural integrity of cell membranes. RBM14C12 is also utilized in the development of innovative compounds aimed at modulating biological mechanisms associated with lipid-related diseases. -
Endogenous Metabolite
C22 Galactosylceramide is a sphingolipid that functions as an endogenous metabolite with significant roles in the central nervous system. Notably elevated in the spinal cord of mice on a methionine-restricted diet, this compound does not influence levels in the brain or liver. Additionally, it has been detected in the postmortem hippocampus of Alzheimer's disease patients, making it a valuable target for research associated with neurodegenerative conditions. -
Endogenous Metabolite
Iretol (2,4,6-trihydroxyanisole) is an endogenous metabolite and a degradation product derived from a glucoside found in Iris jorentina. It serves as an important intermediate in the biosynthesis of natural isoflavones, including Tectorigenin, Irigenin, and Caviunin. This compound is utilized in various research applications focused on natural product synthesis and the study of isoflavonoid pathways. -
Endogenous Metabolite
C24:1 Dihydro 1-deoxyceramide (m18:0/24:1) is an endogenous metabolite characterized by a long-chain fatty acid (24:1) and a 1-deoxysphingoid backbone. This lipid molecule is known to accumulate in conditions such as obesity and type 2 diabetes (T2D), and its accumulation can be toxic due to its inability to be further metabolized into complex sphingolipids. C24:1 dihydro 1-deoxyceramide has been shown to increase in differentiated adipocytes in vitro, making it relevant for research into metabolic disorders and lipid metabolism. -
Endogenous Metabolite
XR5944 is a potent topoisomerase inhibitor that targets DNA, demonstrating significant anti-tumor activity. It effectively inhibits the activities of both topoisomerase I and II, showcasing impressive potency across various cell lines, with IC50 values ranging from 0.04 to 0.4 nM. XR5944 remains effective in overcoming atypical drug resistance mechanisms, including cells overexpressing P-glycoprotein and multidrug resistance-related proteins. This compound has shown remarkable anti-tumor efficacy in preclinical models of H69 small cell lung cancer and HT29 colon cancer, inducing tumor regression in multiple cases. XR5944 is valuable for research on colon and lung cancer biological processes. -
Endogenous Metabolite
Dihydroxyfumaric acid hydrate is an endogenous metabolite that plays a crucial role in cellular metabolism, particularly in the tricarboxylic acid cycle. It has been studied for its potential antioxidant properties and its involvement in modulating metabolic pathways. This compound is used in research exploring metabolic disorders and neurodegenerative diseases, providing insights into cellular function and potential therapeutic approaches. -
Endogenous Metabolite
2-Ethylpyrazine is an endogenous metabolite known for its role in various metabolic pathways. This compound exhibits biological activity relevant to flavor and aroma profiles in food chemistry and is studied for its potential implications in metabolic disorders. Its applications in research include examining biosynthetic mechanisms and evaluating metabolic processes in various biological systems. -
Fungal Metabolites
5-Hydroxyvanillin is a derivative of ferulic acid, produced by the metabolic processes of various fungi and bacteria. This compound exhibits antioxidant properties and has been shown to have potential anti-inflammatory effects. It is widely used in research related to fungal metabolites, functional foods, and the exploration of natural product chemistry. -
Endogenous Metabolite
TRC210258 is a potent TGR5 agonist that plays a critical role in modulating glucose and lipid metabolism. This compound enhances energy expenditure by promoting the secretion of glucagon-like peptide-1, leading to improved control of hyperglycemia and dyslipidemia in models of diet-induced obesity. Additionally, TRC210258 has demonstrated the ability to reduce plasma triglycerides and low-density lipoprotein cholesterol levels, thereby positively influencing lipid-related cardiovascular risk factors such as remnant cholesterol and triglyceride clearance. Its application in metabolic research highlights its potential for therapeutic intervention in metabolic disorders. -
Endogenous Metabolite
Myricanone is an endogenous metabolite isolated from the bark of Myrica rubra. This compound exhibits potential biological activity, including antioxidant and anti-inflammatory properties. It is primarily utilized in research applications investigating metabolic pathways, natural product studies, and the exploration of its effects on cellular functions. -
Endogenous Metabolite
2-Phenylglycine is an endogenous metabolite known to be present in breast milk during the lactation period from weeks 2 to 4. This compound plays a significant role in metabolic processes and is often used in research applications related to lactation and infant nutrition. Its analysis can provide insights into the nutritional profile of breast milk and its impact on infant development. -
Endogenous Metabolite
Lacto-N-biose I (Galβ1-3GlcNAc) is an endogenous metabolite that serves as an acceptor for the α1,2-fucosyltransferase enzyme derived from Helicobacter pylori. This compound plays a critical role in glycan biosynthesis and is relevant in studies of bacterial adhesion and host-pathogen interactions. Lacto-N-biose I is valuable for research focused on glycosylation processes and microbial pathogenicity. -
Endogenous Metabolite
2,3,5-Trimethylpyrazine is an endogenous metabolite known for its role in various metabolic pathways. This compound exhibits biological activity that may influence physiological processes and is utilized in research exploring metabolic functions and pathways. Its presence in different biological samples makes it a valuable reagent for studies in metabolomics and related fields. -
Endogenous Metabolite
2-Naphthoxyacetic acid is an endogenous metabolite that acts primarily as a growth regulator in plant physiology. Its biological activity includes modulating auxin responses, which are crucial for various developmental processes in plants. This compound is commonly utilized in research applications focused on plant growth regulation and the biochemical pathways of auxin signaling. -
Endogenous Metabolite
(Z)-4-Amino-4-oxobut-2-enoic acid acts as an endogenous metabolite involved in various biochemical pathways. It is a key component in the metabolic processes of amino acids and can influence neurotransmitter synthesis. This compound is valuable for research applications focused on metabolic regulation and neurobiology, providing insights into physiological and pathological states. -
Endogenous Metabolite
3,4-Dimethoxyphenylacetic acid is an endogenous metabolite that serves as a key building block in chemical synthesis. It exhibits important biological activity, playing a role in the synthesis of various phenolic compounds. This compound is utilized in research applications focused on metabolic pathways and the exploration of biochemical processes involving phenolic precursors. -
Endogenous Metabolite
trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite involved in fatty acid metabolism. It serves as a fatty acyl-CoA analogue, playing a key role in the transport of long-chain fatty acids into the mitochondria for β-oxidation. This compound is useful in research focused on metabolic disorders and energy metabolism, providing insights into cellular energy homeostasis and lipid metabolism. -
Endogenous Metabolite
Deoxypyridinoline is an endogenous metabolite that serves as a biomarker for bone turnover and metabolism. Its primary mechanism involves crosslinking of collagen, which is essential for maintaining bone strength and integrity. This compound is mainly utilized in research to investigate conditions related to bone disease and heart failure, providing insights into the pathophysiological mechanisms underlying these disorders. -
Endogenous Metabolite
4-Methyloctanoic acid is an endogenous metabolite that plays a significant role in the flavor profile of sheep and goat milk, contributing to its distinctive goaty and sheepy taste. This compound is utilized in studies investigating flavor chemistry and the metabolic pathways associated with fatty acid production in dairy animals. Additionally, it may be relevant in exploring the impacts of diet on milk composition and sensory characteristics. -
Endogenous Metabolite
5-Methyltetrahydrofolic acid disodium is a vital endogenous metabolite involved in one-carbon metabolism and the transfer of methyl groups. It plays a critical role in nucleotide synthesis and amino acid metabolism, making it essential for cellular proliferation and growth. Research applications include studies on folate deficiency, methylation processes, and various metabolic disorders. -
Endogenous Metabolite
4-Hydroxy-3-methylbenzoic acid is an endogenous metabolite with pivotal roles in various biochemical pathways. Its detection in biological fluids, particularly urine, serves as a biomarker for metabolic processes in human health. This compound is utilized in research focusing on metabolism, toxicology, and disease state assessment. Its relevance in clinical studies underscores its potential in understanding metabolic disorders and monitoring physiological changes. -
Endogenous Metabolite
11-Hexadecenoic acid is a monounsaturated fatty acid that functions as an endogenous metabolite. This compound exists in two geometric isomers, 11-cis-hexadecenoic acid and 11-trans-hexadecenoic acid, which are found in ewe milk fat and are influenced by dietary lipid supplementation from sources such as linseed, sunflower, olive, or fish oils. Additionally, 11-trans-hexadecenoic acid has been identified in intramuscular fat from both male and female foals. This reagent serves as a valuable tool for research into lipid metabolism and fatty acid profiles. -
Endogenous Metabolite
C18:1 Cyclic LPA is an endogenous metabolite that serves as an analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). Its distinctive 5-membered ring structure, formed between the sn-2 hydroxy group and the sn-3 phosphate, enables C18:1 Cyclic LPA to modulate various cellular functions. Key biological activities include the inhibition of cell cycle progression, promotion of stress fiber formation, and reduction of tumor cell invasiveness and metastasis. Additionally, it influences the differentiation and survival of neuronal cells, often yielding effects that oppose those induced by LPA, despite engaging similar receptor populations. -
Endogenous Metabolite
AC-PHE-OME is a derivative of phenylalanine that serves as an endogenous metabolite. This compound is primarily utilized to study metabolic pathways involving phenylalanine and its derivatives. Its key biological activity includes functioning as a substrate in various enzymatic reactions, making it valuable for research in metabolic disorders and related biochemical processes. -
Endogenous Metabolite
(S)-OPC-51803 acts as an agonist for the vasopressin V2 receptor, primarily targeting the regulation of renal water reabsorption. This compound demonstrates significant biological activity in suppressing nocturia and urinary incontinence, exhibiting a stronger agonistic effect than its (R)-isomer. Research applications include studies on urinary function disorders and potential therapeutic interventions for conditions associated with nocturnal polyuria. -
Endogenous Metabolite
N-Lignoceroyl Taurine is an endogenous metabolite and taurine conjugate of lignoceric acid, identified through lipidomic analysis of bovine brain. This compound exhibits distinct biological activity as a substrate for fatty acid amide hydrolase (FAAH), with levels significantly elevated in FAAH knockout mice, indicating a potential role in lipid metabolism. Additionally, N-Lignoceroyl Taurine has been shown to activate transient receptor potential (TRP) calcium channels, including TRPV1 and TRPV4, highlighting its relevance in neurobiology and cellular signaling research. -
Endogenous Metabolite
5-OAHSA is an endogenous metabolite that functions as a lipid mediator. It is known to lower blood glucose levels, enhance glucose tolerance, and stimulate the secretion of glucagon-like peptide-1 (GLP-1) and insulin. 5-OAHSA is valuable for research applications focused on metabolic regulation and inflammation modulation. -
Endogenous Metabolite
Magnesium Ionophore I primarily functions as a carrier for magnesium ions, facilitating their transport across lipid membranes. This compound is essential in the development of calcium-magnesium selective electrodes, enabling precise measurement and analysis of ion concentrations in various biological samples. Its unique properties make it a valuable tool in studies involving ion transport and signaling pathways. -
Endogenous Metabolite
13,14-Dihydro-15-keto Prostaglandin F2α is an endogenous metabolite that primarily targets prostaglandin pathways. It plays a significant role in various biological processes related to pregnancy and reproductive health. This compound is instrumental in research applications focused on understanding the biochemical mechanisms of pregnancy and potential implications in related disorders. -
Endogenous Metabolite
Phosphoglycolic acid is an endogenous metabolite that plays a crucial role in linking photo-respiration with central metabolic pathways. This compound significantly affects the tissue levels of 2-phospho-glycolate, thereby influencing metabolic processes in various biological systems. Research applications include studying plant metabolism, photo-respiratory pathways, and their impact on overall plant physiological responses.
