Click Chemistry

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  1. Biochemical Assay Reagent

    Dodecyl azide (1-Azidododecane) is a biochemical assay reagent featuring an azide functional group linked to a 12-carbon alkyl chain. It demonstrates the ability to undergo click chemistry reactions, specifically with alkynes, BCN, and DBCO. This compound is valuable for applications in bioconjugation and labeling studies, enabling researchers to investigate various biological interactions and pathways.
  2. Spermidine Probe

    Spermidine-alkyne is a derivative of spermidine featuring an alkyne functional group, serving as a valuable probe for studying spermidine interactions. This compound enables the investigation of spermidine binding to cellular proteins, providing insights into cellular processes and signaling pathways. Researchers can utilize spermidine-alkyne in various applications, including proteomics and chemical biology studies, to delineate the role of spermidine in biological systems.
  3. Biochemical Assay Reagent

    (E,E,E)-Farnesyl alcohol azide is a versatile biochemical assay reagent that serves as a precursor for the synthesis of C15-Azide analogs. This compound plays a crucial role in various chemical biology applications, enabling researchers to study azide functionalization and facilitate click chemistry reactions. Its unique structure allows for incorporation into biomolecules, thus aiding in the investigation of protein labeling and modification techniques.
  4. Biochemical Reagent

    DBCO-Palmitic is a reactive biochemical reagent that functions as a click chemical under the azide-alkyne cycloaddition mechanism. This compound is particularly useful for labeling and modifying biomolecules through SPAAC reactions, facilitating the study of various biological processes. Its applications include bioconjugation methods and tracking of molecular interactions in live-cell imaging.
  5. Click Chemical

    (R,E)-TCO-NHS Ester is a Click chemical reagent designed for the selective labeling of amine-containing compounds and biomolecules. This compound features a TCO moiety that participates in an inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-labeled molecules. Its high reactivity and specificity make it suitable for various applications in bioconjugation, chemical biology, and drug discovery.
  6. PEG Derivative

    Biotin-PEG10-azide is a PEG derivative featuring biotin, 10 polyethylene glycol units, and an azide moiety. The biotin component facilitates stable non-covalent interactions with streptavidin, while the azide functional group allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. Additionally, the azide can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN derivatives. This reagent is suitable for diverse applications in bioconjugation, labeling, and biomolecule tracking in chemical biology research.
  7. Click chemistry intermediate

    DBCO-Sulfo-Link-biotin TEA serves as a click chemistry intermediate featuring a dibenzocyclooctyne (DBCO) group, enabling efficient ring strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This reagent is primarily used for bioconjugation applications, facilitating the labeling of biomolecules with biotin for downstream interactions and assays. Its high specificity and reactivity make it valuable in chemical biology and protein engineering studies.
  8. Azide

    4-Hydroxynonenal alkyne is a click chemical reagent that features alkynes and targets azides for bioorthogonal labeling. This compound induces heme oxygenase activity and promotes apoptosis in colon cancer (RKO) cells, making it a valuable tool for investigating oxidative stress and related cellular processes. Its applications extend to studying lipid peroxidation and the mechanism of action in cancer research.
  9. Biotinylation Agent

    Biotin-XX hydrazide is a carbonyl-reactive biotinylation agent designed to facilitate the conjugation of biotin to various biomolecules. Featuring two aminohexanoic acid spacers, this reagent enhances avidin-binding efficiency, making it an effective tool for a wide range of research applications, including protein labeling and immobilization studies. Its utility is critical for assays that require precise detection and quantification of biotinylated targets.
  10. Biochemical Assay Reagent

    Desthiobiotin-PEG4-alkyne is a biotinylated biochemical reagent designed for use in click chemistry applications. This compound enables the selective labeling and enrichment of specific tRNAs, facilitating the study of tRNA dynamics and interactions. It is a valuable tool for researchers exploring RNA biology and related biochemical pathways.
  11. PEG Derivative

    Cholesterol-PEG3-azide is a PEG derivative that incorporates cholesterol, three polyethylene glycol (PEG) units, and an azide moiety. This compound participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with entities bearing DBCO or BCN groups. It is valuable for bioconjugation applications, including the development of lipidated probes and drug delivery systems within biological research.
  12. Sphingosine Alkyne

    Sphingosine (d18:1) alkyne is an alkyne-modified sphingosine derivative designed for applications in click chemistry. This compound facilitates the study of sphingolipid metabolism and signaling pathways by allowing researchers to label sphingosine in cellular systems. Its structure enables selective and efficient conjugation with various biomolecules, expanding the toolkit for investigating lipid interactions and functions in biological research.
  13. cyclo(RGDfK) Derivative

    DBCO-cyclo(RGDfK) is a derivative of the cyclo(RGDfK) peptide that incorporates a DBCO (dibenzocyclooctyne) moiety. This compound functions as a clickable ligand for targeting integrins, facilitating the study of cell adhesion and migration. Its unique structure enables applications in bioconjugation and drug delivery systems, particularly in cancer research and tissue engineering.
  14. Click Chemistry Reagent

    TCO-PEG3-acid is a click chemistry reagent featuring a trans-cyclooctene (TCO) moiety that participates in inverse electron demand Diels-Alder (iEDDA) reactions with tetrazine-containing molecules. This compound is applicable in bioconjugation and labeling studies, facilitating the development of targeted therapies and imaging agents. Its utility in the rapid and selective formation of covalent bonds makes it a valuable tool in chemical biology and biomedical research.
  15. Biochemical Assay Reagents

    DBCO-propargyl-PEG5-TFP ester is an amine-reactive labeling reagent featuring a DBCO group. This compound is designed for bioconjugation applications, specifically enabling strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing biomolecules. Its versatile chemistry makes it suitable for a variety of biochemical assays and targeted labeling studies in molecular biology and biochemistry.
  16. Click Chemistry Compound

    (3aS,4S,6aR)-Biotin-PEG4-Alkyne is a biotinylation reagent featuring an alkyne functional group, designed for applications in click chemistry. This compound facilitates the conjugation of azides through a copper-catalyzed click reaction, enabling the labeling of biomolecules with biotin. The resulting biotinylated constructs can effectively interact with avidin or streptavidin, making this reagent valuable for purification and detection assays in biochemical research.
  17. Biochemical Assay Reagent

    Biotin-PEG8-azide is a chemical reagent designed for click chemistry applications, enabling the biotinylation of macromolecules. This compound facilitates the selective labeling of proteins, nucleic acids, and other biomolecules, allowing for enhanced detection and purification in biochemical assays. Its utility in diverse research applications includes studying protein-protein interactions and tracing biological pathways.
  18. Click Chemistry Compound

    Biotin-PEG8-Alkyne is a click chemistry compound designed for efficient bioconjugation through azide-alkyne cycloaddition. This reagent facilitates the direct labeling of biomolecules and can be utilized in various applications, including protein tagging, cellular imaging, and the development of bioconjugates. Its biotinylated structure enhances binding affinity to streptavidin, making it a powerful tool for studying protein interactions and tracking biomolecules in complex biological systems.
  19. Biochemical Assay Reagent

    Biotin-PEG2-alkyne is a biochemical assay reagent designed to facilitate affinity-based applications. This compound features a biotin group for effective binding in assays such as pull-down assays, combined with a terminal alkyne that allows for copper (I) catalyzed click chemistry with azides. It is suitable for various research applications, including protein labeling and tracking.
  20. Glycobiology

    2-Acetamido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-β-D-glucopyranosyl azide is a specialized biochemical reagent targeting glycobiology. This compound is instrumental in the study of glycan structure and function, facilitating research into carbohydrate chemistry, glycan synthesis and degradation, and protein-glycan interactions. Its applications are pivotal in advancing understanding in biomedicine and biotechnology, contributing to the exploration of the roles glycans play in biological systems.
  21. Cross-linking Agent

    Mal-b-Lys(mal)-PEG4-amide-PEG3-azide is a versatile cross-linking agent that facilitates the conjugation of antibodies. This compound is particularly useful for the synthesis of antibody-drug conjugates (ADCs), enabling targeted delivery of therapeutic agents. Its unique structure allows for effective and selective cross-linking, making it valuable in various biochemical and biophysical research applications.
  22. Biochemical Assay Reagent

    DBCO-NHCO-C5-O-phenylethenesulfonyl fluoride is a versatile DBCO-containing linker designed for efficient bioconjugation. This reagent enables precise attachment of biomolecules and facilitates drug delivery applications. Its unique chemical structure allows for site-specific labeling in biochemical assays, making it a valuable tool in various research settings focused on protein interactions and cellular mechanisms.
  23. Sugar

    2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide is a glycosyl azide derivative targeting glycobiology applications. This compound serves as a versatile substrate for the investigation of enzyme activity, facilitating research in carbohydrate biochemistry. Its high purity of 98% ensures reliable results in experimental settings.
  24. Lipid

    16:0 DBCO PE ammonium is a phosphatidylethanolamine (PE) derivative featuring a reactive dibenzocyclooctyne (DBCO) moiety. This functionalized lipid serves as a valuable click chemistry reagent, facilitating strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. It is ideally suited for applications in bioconjugation, lipid modification, and the development of lipid-based delivery systems in biochemical research.
  25. Biotin Derivative

    Biotin N-(bromoacetyl)hydrazide is a biotin derivative that serves as a valuable tool for labeling and detecting biomolecules. This compound is instrumental in bioconjugation studies where it can facilitate the attachment of biotin to proteins, peptides, or other macromolecules. Its applications extend to various research fields, including proteomics, cellular imaging, and the development of biotin-affinity purification methods.
  26. Biochemical Assay Reagent

    β-D-Glucopyranosyl azide, 2-(acetylamino)-2-deoxy, 3,4,6-triacetate is a biochemical assay reagent that serves as a versatile tool for glycosylation studies. It enables the exploration of glycosylation patterns and interactions in various biological systems. This compound is particularly useful in the development of glycoengineered therapeutics and for elucidating the roles of glycoconjugates in cellular processes.
  27. Biochemical Assay Reagent

    Azide-C3-NHCO-C3-NHS ester serves as a versatile linker in biochemical assays, facilitating efficient and specific ligation through click chemistry. This reagent is ideal for applications in protein labeling, biomolecule modification, and the development of complex biochemical systems. Its reactive nature makes it a valuable tool for researchers engaged in chemical synthesis and functionalization studies.
  28. Biochemical Reagent

    Pent-4-ynehydrazide is a biochemical reagent employed as an intermediate in organic synthesis. It serves as a valuable precursor for the synthesis of Hydrazone-DOX-Alkyne. This compound is particularly relevant in cancer research, facilitating the exploration of therapeutic applications and development of novel treatment strategies.
  29. Biochemical Assay Reagent

    DBCO-amine TFA is a versatile biochemical assay reagent featuring a DBCO moiety linked to an amine group. The amine exhibits high reactivity with NHS esters, facilitating the formation of stable covalent bonds. This compound is widely utilized in copper-free Click Chemistry reactions, enabling efficient labeling and conjugation in various biochemical applications.
  30. Glycobiology

    3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-α-D-glucopyranosyl azide is a specialized reagent utilized in glycobiology, focusing on the study of carbohydrate structures and their biological significance. It facilitates research on glycan synthesis and recognition, contributing to the understanding of glycan-related processes in various biological systems. This compound is essential for investigating the roles of glycans in health and disease, making it a valuable tool for researchers in the fields of biomedicine and biotechnology.
  31. Glycobiology

    Hepta-O-acetyl-β-lactosyl azide is a biochemical reagent that acts as a reliable substrate for glycosyltransferases in glycobiology research. This compound facilitates the study of glycan structure and function by enabling the synthesis and analysis of glycan-related biomolecules. Its applications extend to carbohydrate chemistry, enzymology, and the investigation of protein-glycan interactions, aiding in the understanding of the biological roles of glycans in various systems.
  32. Biochemical Assay Reagents

    2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl azide serves as a biochemical reagent in glycobiology research. This compound facilitates the study of carbohydrate chemistry, glycan synthesis and degradation, as well as protein-glycan interactions. Its application extends to essential areas in basic research, biomedicine, and biotechnology, enabling deeper exploration of the role of glycans in biological systems.
  33. click chemistry reagent

    PreQ1-alkyne is a click chemistry reagent featuring an alkyne functionality that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions. This compound is pivotal for bioconjugation applications, allowing for the selective labeling and modification of biomolecules containing azide groups. Its utility extends to the synthesis of complex biomolecular structures in chemical biology and materials science research.
  34. Lipid

    18:1 DBCO PE ammonium is a functionalized lipid that features a reactive dibenzocyclooctyne (DBCO) moiety and phosphatidylethanolamine (PE) backbone. This reagent is utilized in click chemistry applications, particularly in strain-promoted alkyne-azide cycloaddition (SPAAC), allowing for efficient and bioorthogonal labeling of azide-containing molecules. Its biocompatible properties enhance its utility in various biological research applications, including targeted drug delivery and cellular imaging.
  35. PEG Derivative

    Methyltetrazine-PEG4-amine is a PEG derivative featuring a free amine and a methyltetrazine moiety. As a versatile click chemistry reagent, it facilitates the inverse electron demand Diels-Alder (iEDDA) reaction with trans-cyclooctene (TCO) containing compounds. This reagent can be employed in bioconjugation strategies, enabling the development of targeted therapeutics and imaging agents in chemical biology research.
  36. Biochemical Assay Reagent

    Methyltetrazine-PEG5-sulfo-NHS ester sodium is a versatile biochemical assay reagent that functions primarily as a crosslinker for biomolecules. This compound enables efficient conjugation with amine-containing molecules, facilitating the study of protein interactions and modifications. Its solubility in aqueous environments increases its applicability in various biological assays and research applications, making it a valuable tool in chemical biology and bioconjugation techniques.
  37. Biochemical Assay Reagent

    3-Chlorophenylacetylhydrazide functions as a biochemical assay reagent, essential for various life science research applications. This compound is utilized as a biological material, facilitating the study of hydrazine derivatives and their interactions in biochemical assays. Its properties make it valuable for exploring enzymatic activities and metabolic processes in cellular systems.
  38. Biochemical Assay Reagent

    2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide is a click chemistry reagent featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing compounds, such as DBCO and BCN. This compound serves as a valuable biochemical assay reagent in various life science research applications, particularly in glycosylation studies and bioconjugation. Its stable acetylated form enhances solubility and reactivity, making it an effective tool for the synthesis of complex biomolecules and labeled substrates.
  39. PEG Derivative

    Azide-PEG4-Desthiobiotin is a polyethylene glycol (PEG) derivative featuring an azide group and desthiobiotin. This reagent enables stable non-covalent interactions with streptavidin, facilitating applications in bioconjugation and biomolecular labeling. It is suitable for click chemistry, undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties.
  40. UDP-GlcNAc Derivative

    UDP-2-alkyne-GlcNAc is a derivative of UDP-GlcNAc, targeting glycosylation processes. This compound serves as a crucial tool for the remodeling of cell surface glycans, enabling researchers to study glycan structures and functions in various biological contexts. It is particularly useful in applications such as metabolic labeling and click chemistry for the visualization of glycoproteins and glycoconjugates.
  41. Clickable Phospholipid

    16:0(Alkyne)-18:1 PE is a clickable phospholipid designed for use in click chemistry applications. This compound facilitates the conjugation of biomolecules, allowing for the study of lipid interactions and cellular uptake dynamics. Its unique alkyne functionality enables efficient labeling and tracking of phospholipid structures in various biological systems, making it a valuable tool for researchers in lipidomics and membrane biology.
  42. Glycobiology

    2-Acetamido-2-deoxy-β-D-glucopyranosyl azide is a biochemical reagent utilized in glycobiology to explore glycan structures and functions. It plays a critical role in studying carbohydrate chemistry, enzymatic processes involved in glycan formation and degradation, and protein-glycan interactions. This compound supports various research applications within basic biological research, biomedicine, and biotechnological advancements.
  43. Click Chemistry

    4-Oxo-2-Nonenal Alkyne is a functionalized lipid electrophile designed for click chemistry applications. It facilitates the conjugation to exosomes through the reaction of amino and aldehyde groups. This reagent is particularly useful for the determination and characterization of tumor-derived exosomes in various biological research settings.
  44. Linker

    DOTA-PEG4-alkyne is a bifunctional linker designed for efficient conjugation with radionuclides. It facilitates the creation of radiolabeled biomolecules, enabling precise imaging and therapeutic applications in molecular biology and nuclear medicine. Its PEGylated structure enhances solubility and biocompatibility, making it suitable for various research applications, including drug delivery and targeted therapy.
  45. Biochemical Reagent

    11-Maleimidoundecanoic acid hydrazide is a biochemical reagent characterized by its maleimide group, which facilitates selective covalent conjugation to thiol-containing biomolecules. This compound is primarily utilized in bioconjugation applications, enabling the development of targeted therapeutics and diagnostic tools. Its ability to form stable linkages with proteins and peptides makes it a valuable resource for researchers studying protein interactions and creating antibody conjugates.
  46. PEG Derivative

    Endo-BCN-PEG2-Biotin is a PEG derivative featuring a bicyclo[6.1.0]nonyne (BCN) group that enables efficient clicking with azide-modified compounds. Its terminal carboxylic acid group facilitates reactivity with various functional groups, including amino acids, activated NHS esters, and carbonyls, enhancing conjugation versatility. This reagent is valuable for bioconjugation applications, such as protein labeling and drug delivery, supporting studies in chemical biology and therapeutics.
  47. Biochemical Assay Reagent

    Endo-BCN CE-phosphoramidite is a highly reactive cyclooctyne utilized in copper-free click chemistry. Its unique reactivity allows for efficient strain-promoted azide-alkyne cycloaddition (SPAAC) and inverse electron demand Diels-Alder reactions (IEDDA) with azides and tetrazines, respectively. This chemical reagent is ideal for a variety of biochemical assays, enabling bioconjugation and labeling applications in chemical biology and drug development research.
  48. Click Chemistry Reagent

    Sulfo-DBCO-NHS ester is a click chemistry reagent featuring an azide group and a DBCO moiety, which facilitates copper-free Click Chemistry reactions through its strain-promoted mechanism. This reagent exhibits high reactivity with amino acids and other molecules possessing amino groups via the NHS ester linkage, making it valuable for bioconjugation and labeling applications in chemical biology. Its ability to enable precise and efficient conjugation makes it suitable for a variety of research applications, including the development of therapeutics and diagnostics.
  49. Lipid

    C16:0(Alkyne) L-carnitine is an acyl carnitine lipid that features a terminal alkyne group, serving as a valuable tool for click chemistry applications. This reagent facilitates specific reactions with azide-containing compounds in the presence of a copper catalyst, enabling efficient linkage in various biochemical studies. Its unique structure allows for functionalization and the investigation of lipid-related biological processes, making it suitable for research in cellular metabolism and lipid signaling.
  50. Lipid

    DSPE-PEG8 DBCO is a click chemistry reagent featuring a DBCO moiety that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This reagent is pivotal for the preparation of lipid nanoparticles, enhancing drug delivery systems through novel bioconjugation strategies. Its application in biochemistry and nanotechnology makes it a valuable tool for researchers focused on developing targeted therapy and RNA delivery systems.

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