Catalog No.
Product Name
Application
Product Information
Citations
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Lipid
16:0(Alkyne)-18:1 PC is a clickable phospholipid that enables the study of lipid metabolism and cellular membrane dynamics. This compound serves as a versatile tool for lipid labeling in biological research, facilitating the investigation of membrane-associated processes. It is particularly useful in studies involving lipid droplet formation, membrane trafficking, and the role of phospholipids in cell signaling pathways. -
Biochemical Assay Reagent
TCO-PEG4-maleimide is a click chemistry building block designed for biochemical assays, featuring a trans-cyclooctene (TCO) moiety and a maleimide group. The maleimide moiety exhibits high reactivity with thiol groups, facilitating the formation of stable covalent bonds. This compound is particularly valuable in applications involving 3rd generation click chemistry, where the TCO moiety interacts efficiently with tetrazine derivatives, enabling versatile labeling and tagging strategies in biochemical research. -
Biochemical Assay Reagent
Azide-PEG5-Ms is a PEG-based linker designed for use in biochemical assays, featuring an azide group that undergoes Click Chemistry with BCN, DBCO, and alkynes. The mesyl group serves as an effective leaving group for nucleophilic substitution reactions, enhancing the versatility of this reagent. The polyethylene glycol (PEG) spacer provides improved water solubility, making it suitable for a variety of biological applications, including bioconjugation and drug delivery studies. -
Biochemical Assay Reagent
27-Alkyne cholesterol is a modified lipid featuring an omega-terminal alkyne, enabling its application as a biochemical assay reagent. This compound participates in click chemistry with azide-containing reagents in the presence of copper catalysts, facilitating highly specific linking reactions. As a versatile tool for investigating cellular cholesterol metabolism and localization, 27-alkyne cholesterol supports various detection methods, including mass spectrometry and fluorescence microscopy. Its sensitive and user-friendly properties make it ideal for diverse research applications in lipid biology. -
Biochemical Assay Reagent
Tco-PEG2-Tco is a bifunctional reagent featuring TCO groups at both termini, which engage in selective and efficient reactions with tetrazine. The inclusion of a hydrophilic PEG linker enhances the solubility of the compound in aqueous environments, making it suitable for various biochemical assays. This reagent is ideal for applications requiring bioconjugation or labeling of biomolecules in research studies. -
For Oligo-Nucleotides Synthesis
Alkyne Phosphoramidite, 5'-terminal is a specialized reagent designed for the synthesis of oligo-nucleotides. This compound enables the incorporation of alkyne groups at the 5' terminus, facilitating subsequent functionalization and applications in bioconjugation strategies. It is invaluable for researchers focused on nucleic acid chemistry and related biotechnological applications. -
Biochemical Assay Reagent
Azido-PEG1-hydrazide hydrochloride is a bifunctional polyethylene glycol linker featuring both azide and hydrazide groups. The azide portion facilitates reactions with alkyne, BCN, and DBCO through Click Chemistry, allowing the formation of stable triazole linkages. Meanwhile, the hydrazine moiety can react with aldehydes to produce semi-permanent hydrazone bonds. This reagent is valuable for biochemical assays and in the development of bioconjugates, enhancing the versatility of molecular modifications in research applications. -
Strained Cycloalkyne-based Probe
BCN-E-BCN is a strained cycloalkyne-based probe that selectively targets sulfenic acid groups, marking an essential intermediate in protein oxidation. This compound effectively detects protein sulfenylation by remaining inert to other oxidative states, including free thiols and sulfinic or sulfonic acid groups. Its design enables efficient conjugation with azide-bearing tags via copper-free click chemistry, enhancing detection sensitivity and reaction kinetics. BCN-E-BCN serves as a valuable tool for advancing research into protein oxidation and its biological implications. -
Ester Product
13(S)-Hydroxy-9(Z),11(E)-octadecadiene-(2-biotinyl)hydrazide is an ester product that acts as a fatty acid derivative. This compound is utilized in various biochemical assays and research applications focusing on lipid metabolism and signaling pathways. Its biotinylation allows for specific labeling and detection in cellular experiments, facilitating studies in cell biology and biochemistry. -
Biochemical Assay Reagent
Alkyne sphinganine is a biochemical assay reagent that features a terminal alkyne group, enabling the selective tagging of protein-lipid complexes through click chemistry. This compound facilitates a highly specific reaction with azide-containing reagents in the presence of a copper catalyst, allowing for the visualization and proteomic profiling of protein-sphingolipid interactions in living cells. Its application in metabolic labeling contributes significantly to the understanding of lipid biology and cellular dynamics. -
Biochemical Assay Reagents
Pentanehydrazide, also known as valeric acid hydrazide, functions as an effective alkylating agent in biochemical assays. It participates in copper-catalyzed oxidative cyclization reactions of N-arylacrylamides and is capable of facilitating tandem acylation processes. Its chemical properties make it a valuable tool in synthetic organic chemistry and various research applications. -
Biochemical Assay Reagent
5-(Tetrahydro-2H-pyran-2-yloxy)pent-3-yn-1-peg4-azide is an azide-functionalized reagent designed for biochemical assays and bioorthogonal reactions. This compound facilitates click chemistry applications, enabling efficient labeling and tracking of biomolecules. Its unique structure allows for versatile applications in chemical biology and bioconjugation studies, making it ideal for researchers investigating molecular interactions and biological pathways. -
Phosphorous Amide Monomer
Alkyne amidite, hydroxyprolinol is a phosphorous amide monomer designed for oligonucleotide synthesis. This reagent facilitates the incorporation of alkyne functionalities into nucleic acid structures, enabling various applications in bioconjugation and probe development. Its unique properties make it a valuable tool for researchers focused on nucleic acid chemistry and related fields. -
Biochemical Assay Reagent
DBCO-PEG6-NH-Boc is a biochemical assay reagent featuring a dibenzocyclooctyne (DBCO) functional group attached to a Boc-protected amine via a polyethylene glycol (PEG) linker. The DBCO group enables efficient copper-free click chemistry reactions with azides, facilitating bioconjugation in a range of biological contexts. The hydrophilic PEG linker enhances the compound’s water solubility, making it suitable for diverse applications in biomolecular research and drug development. The Boc protecting group can be easily removed under acidic conditions, allowing for versatile modifications in experimental setups. -
Click Chemistry Agent
Losartan azide is a click chemistry agent featuring an azide functional group, serving as a synthetic intermediate in the development of angiotensin AT1 receptor-targeted renal imaging probes. It is primarily employed in the synthesis of [18F]fluoropyridine-losartan for positron emission tomography (PET) imaging applications. This reagent is useful in the investigation of renal function and cardiovascular diseases, facilitating advanced research in diagnostic imaging. -
Biochemical Assay Reagent
Azido-PEG12-azide is a biochemically active PEG-based linker featuring two azide groups. This compound facilitates Click Chemistry reactions with alkynes, BCN, or DBCO, resulting in the formation of a stable triazole linkage. It is particularly useful in applications involving bioconjugation, labeling, and the synthesis of complex biomolecules for various research purposes. -
Biochemical Assay Reagent
Alkyne maleimide is a bifunctional linker reagent characterized by a terminal maleimide group and a propargyl group. The maleimide group effectively reacts with thiol groups to form stable covalent bonds, facilitating the conjugation of biomolecules containing thiols. Additionally, the propargyl group enables specific labeling of azide-containing biomolecules through Click Chemistry. This reagent is widely used in biochemical assays and protein labeling applications. -
Biochemical Assay Reagent
N-(TCO)-N-bis(PEG4-acid) is a versatile click chemistry reagent featuring a terminal trans-cyclooctene (TCO) group and two terminal carboxylic acid moieties. This compound facilitates the formation of stable covalent bonds through inverse-electron demand Diels-Alder cycloaddition with tetrazine-containing molecules, representing one of the fastest and most selective bioorthogonal reactions. The carboxylic acids can also efficiently react with primary amino groups in the presence of common coupling activators, such as EDC or HATU, making this reagent suitable for various biochemical assays and labeling applications in research settings. -
Biochemical Assay Reagent
Hex-5-ynehydrazide is a bifunctional linker reagent featuring a terminal hydrazide group and a propargyl moiety. The hydrazide group facilitates the formation of a semi-permanent hydrazone bond through reaction with aldehydes, enabling stable conjugation in biochemical assays. Additionally, the propargyl group is suitable for selective coupling to azide-containing biomolecules via Click Chemistry, making it a valuable tool for various research applications in chemical biology and bioconjugation studies. -
Biochemical Assay Reagent
Acid-PEG5-Amide-Tri (3-methoxypropanamide-PEG4-Azide) Methane is a branched polyethylene glycol (PEG) linker featuring a terminal carboxylic acid functionality and three terminal azide groups. Its azide moieties facilitate PEGylation through Click Chemistry, making it a valuable reagent for biochemical assays. This compound is ideal for modifying biomolecules and enhancing their solubility or bioactivity in various research applications. -
Drug Intermediate
Cyanoacetohydrazide serves as a pharmaceutical intermediate, primarily utilized in the synthesis of acylhydrazide hydrazone derivatives. These derivatives have demonstrated notable antibacterial and anti-tumor activities, making cyanoacetohydrazide a valuable compound in drug development and medicinal chemistry research. Its versatile applications in synthesizing bioactive compounds contribute significantly to advancing therapeutic strategies. -
Drug Intermediate
DFO-BCN is a chemical intermediate utilized in the synthesis of the PET/CT imaging agent DFO-CPC634 via click chemistry. This compound serves as a valuable tool in radiopharmaceutical development, enabling effective labeling and visualization in molecular imaging studies. Its role as a precursor enhances the efficiency of tracer synthesis, supporting research in diagnostic imaging applications. -
Drug Intermediate
2-Pyridinecarbohydrazide is a versatile building block commonly employed as a drug intermediate in synthetic processes. Its structure allows for diverse modifications, facilitating the development of biologically active compounds. Applications include the synthesis of pharmaceuticals and agrochemicals, making it an essential reagent in chemical research and development. -
Synthetic Intermediate
Nicotinoyl azide serves as a versatile synthetic intermediate, notable for its ability to form high-energy intermediates that generate C-8 adducts with adenosine and guanosine. The compound contains an azide functional group and is amenable to copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in ring strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds featuring DBCO or BCN functionalities, making it valuable for diverse applications in chemical biology and medicinal chemistry. -
Trinitride
(Rac)-Azide-deoxy-ascomycin-O-ethylene is a nitrogen-containing derivative of the macrolide immunosuppressant ascomycin. It functions as a trinitride, exhibiting potential biological activity related to immunosuppression. This compound is primarily utilized in pharmacological research, particularly in the study of immunological responses and the development of novel therapeutic agents targeting immune-related conditions. -
Diuretic Agent
5-Chloro hydrochlorothiazide acts as a diuretic agent by inhibiting sodium reabsorption in the renal tubules, which leads to increased urine output. This compound is primarily utilized in research settings to study fluid regulation, electrolyte balance, and hypertension. Its efficacy in promoting diuresis makes it a valuable tool for investigating renal physiology and cardiovascular health. -
Drug Derivative
Cinnamohydrazide, a derivative of unsaturated carboxylic acids, functions as a precursor to aspartame through enzymatic amination with phenylalanine. This compound exhibits promising potential in diabetes management, as it stimulates insulin secretion, enhances pancreatic β-cell function, and inhibits hepatic gluconeogenesis. Additionally, Cinnamohydrazide promotes glucose uptake, amplifies insulin signaling pathways, delays carbohydrate digestion and glucose absorption, and reduces protein glycation and insulin fibrillation, making it a valuable tool for research in metabolic disorders. -
Paclitaxel Modified With DBCO
Paclitaxel-DBCO is a derivative of Paclitaxel, modified to include a dibenzocyclooctyne (DBCO) linker. This modification enhances its conjugation capabilities, making it suitable for targeted drug delivery applications. Paclitaxel-DBCO retains the cytotoxic properties of the parent compound, thereby facilitating research on its efficacy in cancer therapeutics and nanoparticle formulation studies. It serves as a valuable tool for bioconjugation and drug development in cancer research. -
Derivative of Cholesterol
19-Alkyne Cholesterol is an alkyne-modified derivative of cholesterol that serves as a valuable tool for studying cholesterol localization and subcellular distribution in cellular environments. This compound facilitates the investigation of cholesterol dynamics and its role in membrane biophysics. It is particularly useful in biochemistry and cell biology research applications, enabling insights into cholesterol-related processes and signaling pathways. -
Biochemical Assay Reagent
Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane is a versatile click chemistry reagent designed for biochemical assays, featuring three carboxylic acid groups and a methyltetrazine moiety. It facilitates the formation of stable covalent bonds with TCO-containing compounds through a highly selective inverse-electron demand Diels-Alder cycloaddition reaction, eliminating the need for catalysis or elevated temperatures. Additionally, the terminal carboxylic acid can efficiently couple with primary amines in the presence of activators such as EDC or HATU, forming stable amide bonds for a variety of bioconjugation applications in chemical and biological research. -
Biochemical Assay Reagents
β-GalNAc-PEG4-Azide is a specific ligand for the asialoglycoprotein receptor, linked via a PEG4 spacer and featuring an azide functionality. This compound enables efficient click chemistry applications, facilitating conjugation with various biomolecules for biochemical assays. Its design enhances targeted delivery and is particularly useful in the study of glycoprotein interactions and receptor-mediated endocytosis. -
Biochemical Assay Reagent
Tetra-(amido-PEG10-azide) is a branched polyethylene glycol (PEG) reagent featuring four azide groups at its termini, facilitating PEGylation through Click Chemistry. Its unique structure enhances solubility and stability of biomolecules, making it ideal for biochemical assays and labeling applications. The incorporation of this reagent can significantly improve the pharmacokinetics and bioavailability of therapeutic proteins and peptides in research settings. -
Biochemical Assay Reagent
Octyl azide (1-Azidooctane) is a biochemical assay reagent characterized by an azide functional group and an eight-carbon alkyl chain. The azide group is capable of undergoing Click Chemistry reactions with alkynes, BCN, and DBCO, facilitating the formation of stable triazole linkages. This compound serves as a valuable tool in bioconjugation applications, enabling precise labeling and functionalization in various biochemical studies. -
Biochemical Assay Reagent
N-(acid-PEG10)-N-bis(PEG10-azide) is a versatile PEG reagent featuring a terminal carboxylic acid and dual azide groups. The hydrophilic PEG spacer enhances solubility in aqueous environments, facilitating its use in biochemical assays. Through Click Chemistry, the azide groups can efficiently react with alkynes, BCN, and DBCO to form stable triazole linkages. Additionally, the terminal carboxylic acid can conjugate with primary amines in the presence of coupling agents such as EDC or HATU to create stable amide bonds, making it suitable for various bioconjugation applications. -
Biochemical Assay Reagent
Methyltetrazine-PEG4-DBCO is a versatile biochemical assay reagent featuring a PEG linker, a terminal TCO reactive moiety, and a DBCO group. The DBCO component facilitates copper-free Click Chemistry reactions, enabling efficient bioconjugation. This reagent is ideal for converting azido-containing peptides or proteins into tetrazine-modified counterparts without the need for catalysts or auxiliary reagents, making it a valuable tool for researchers in biochemistry and protein engineering. -
PEG Linker
Azido-PEG8-hydrazide-Boc is a PEG linker featuring an azide moiety and a Boc-protected hydrazide. This compound serves as a versatile reagent for click chemistry applications, specifically undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It is ideal for bioconjugation, enabling the formation of stable conjugates in various biological research applications. -
Biochemical Assay Reagent
Iodoacetamido-PEG6-azide is a biochemical assay reagent featuring a hydrophilic PEG linker with an azide group and a terminal iodoacetamido moiety. The azide moiety can undergo click chemistry reactions with alkynes, BCN, or DBCO to form stable triazole linkages. The iodoacetamido group facilitates covalent binding to thiol groups in cysteine residues, effectively preventing the formation of disulfide bonds in proteins. This compound is ideal for applications in protein labeling, modification, and tracking in biochemical studies. -
Biochemical Assay Reagent
endo-BCN-PEG4-Boc-amine is a PEG-based linker incorporating a bicyclononyne (BCN) group and a Boc-protected amine. This unique structure enables the BCN group to react selectively with azide-tagged biomolecules, facilitating bioconjugation applications. The Boc-protected amine can be deprotected under mild acidic conditions, allowing for further functionalization in biochemical assays and research involving peptide or protein modifications. -
Biochemical Assay Reagent
AZD-PEG2-azide is a biochemical assay reagent featuring an azide functional group appropriate for bioconjugation applications. Its primary mechanism involves reacting with alkyne-containing partners through the click chemistry reaction, facilitating the creation of stable linkages. This reagent is ideal for various life science research applications, including the development of drug delivery systems and probing biological interactions. -
Biochemical Assay Reagent
Azide-PEG8-Tos is a PEG-based linker characterized by the presence of an azide and a tosylate group. The tosylate functions as an effective leaving group, facilitating displacement reactions with nucleophiles, while the azide serves as a component for click chemistry, allowing for selective reactions with terminal alkynes or strained cyclooctynes. This reagent is valuable in biochemical assays and applications requiring precise bioconjugation techniques. -
Biochemical Assay Reagent
Azido-PEG19-azide is a versatile click chemistry reagent characterized by two terminal azide groups. It facilitates efficient conjugation with alkynes, BCN, and DBCO through azide-alkyne cycloaddition reactions. This reagent is widely utilized in biochemical assays and polymer synthesis, enabling the labeling and modification of biomolecules for various research applications. -
Biochemical Assay Reagent
(Acid-PEG10)-Tri-(Azide-PEG10-ethoxymethyl)-methane is a versatile biochemical assay reagent that facilitates Click Chemistry reactions with propargyl, BCN, or DBCO reagents. The carboxylic acid group exhibits reactivity towards primary amino groups when coupled with EDC or HATU, enabling efficient bioconjugation. This reagent is ideal for applications in developing bioconjugates, analyzing protein interactions, and enhancing labeling strategies in biochemical assays. -
Biochemical Assay Reagent
DBCO-N-bis(PEG4-acid) is a branched click chemistry reagent featuring a DBCO group that facilitates copper-free Click Chemistry reactions. Its carboxylic acid functionalities enable efficient coupling with primary amines, utilizing activators such as EDC or HATU to form stable amide bonds. This reagent is ideal for biochemical assays and applications requiring bioconjugation, contributing to the development of diverse biomolecular constructs. -
Biochemical Assay Reagent
t-Boc-aminooxy-pentane-azide is a versatile linker designed for biochemical assays, featuring an azide group and a Boc-protected amino group. The azide moiety enables selective reactions with alkynes, BCN, and DBCO through Click Chemistry, facilitating the formation of stable triazole linkages. Upon mild acidic deprotection, the Boc group is removed, yielding a free amine for further applications in bioconjugation and peptide synthesis. This compound is ideal for use in various chemical biology studies and assay development. -
Biochemical Assay Reagent
4-Azide-TFP-Amide-SS-Sulfo-NHS is a biochemical assay reagent featuring an aryl azide, a cleavable disulfide bond, and an NHS ester. The aryl azide facilitates photo-activation using UV light (250 to 350 nm) for efficient conjugation with biomolecules, while the NHS ester enables targeted coupling with amines. The inclusion of a stabilizing fluorine within the structure aids in the stabilization of the free radical intermediate, and the disulfide bond can be cleaved under reducing conditions, providing versatility in biochemical applications. -
Biochemical Assay Reagent
C18-PEG4-Azide is a hybrid linker that combines a hydrophobic C18 fatty acid chain with a hydrophilic PEG4 spacer and an azide functional group. The azide moiety engages in efficient click chemistry with terminal alkynes or strained cyclooctynes, such as DBCO or BCN. This compound is essential for applications in biochemical assays, facilitating the conjugation of biomolecules and the development of complex molecular probes for various research applications. -
Biochemical Assay Reagent
Mal-amido-PEG5-alkyne functions as a biochemical assay reagent featuring a maleimide group and an alkyne component. This PEG-based linker enhances solubility in aqueous environments while enabling versatile coupling reactions. The alkyne moiety can engage in copper-catalyzed azide-alkyne Click Chemistry, resulting in a stable triazole bond with azide-containing biomolecules. Additionally, the maleimide group facilitates covalent attachment to thiol-containing compounds, making it ideal for applications in bioconjugation and protein labeling studies. -
Biochemical Assay Reagent
Biotinamide-C3-PEG3-C-alkyne is a biotin-conjugated polyethylene glycol (PEG) reagent featuring a terminal alkyne. This compound facilitates efficient coupling through Click Chemistry with various azide-containing molecules, such as BCN and DBCO. It is primarily utilized in biochemical assays for labeling and detecting biomolecules, enhancing the study of biological processes and interactions. -
Biochemical Assay Reagents
2,3,4,6-Tetra-O-acetyl-β-D-mannopyranosyl azide is a chemical compound that serves as a valuable reagent in biochemical assays within glycobiology research. It functions as a glycosyl donor, facilitating the exploration of carbohydrate-protein interactions and the synthesis of oligosaccharides. This compound aids in the development of glycomimetics and other glycan-based applications, contributing to advancements in carbohydrate chemistry and glycan biology. -
Biochemical Assay Reagent
Tri(Azide-PEG10-NHCO-ethyloxyethyl)amine is a branched polyethylene glycol (PEG) linker featuring three terminal azide moieties. This compound facilitates PEGylation through efficient Click Chemistry, making it valuable for various biochemical assay applications. Its unique structure enhances solubility and biocompatibility, supporting the development of diverse bioconjugates in chemical biology and drug formulation studies.
