Catalog No.
Product Name
Application
Product Information
Citations
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Click Chemistry Catalyst
VHLL-BCN serves as a highly effective catalyst for click chemistry reactions, enhancing the efficiency of various bioconjugation processes. Its utility extends to the development of transcription factor (TF)-PROTACs, facilitating targeted protein degradation research. This reagent is essential for researchers focused on innovative therapeutic strategies and the advancement of drug discovery methodologies. -
Biochemical Assay Reagent
Dodecyl azide (1-Azidododecane) is a biochemical assay reagent featuring an azide functional group linked to a 12-carbon alkyl chain. It demonstrates the ability to undergo click chemistry reactions, specifically with alkynes, BCN, and DBCO. This compound is valuable for applications in bioconjugation and labeling studies, enabling researchers to investigate various biological interactions and pathways. -
Spermidine Probe
Spermidine-alkyne is a derivative of spermidine featuring an alkyne functional group, serving as a valuable probe for studying spermidine interactions. This compound enables the investigation of spermidine binding to cellular proteins, providing insights into cellular processes and signaling pathways. Researchers can utilize spermidine-alkyne in various applications, including proteomics and chemical biology studies, to delineate the role of spermidine in biological systems. -
Biochemical Assay Reagent
(E,E,E)-Farnesyl alcohol azide is a versatile biochemical assay reagent that serves as a precursor for the synthesis of C15-Azide analogs. This compound plays a crucial role in various chemical biology applications, enabling researchers to study azide functionalization and facilitate click chemistry reactions. Its unique structure allows for incorporation into biomolecules, thus aiding in the investigation of protein labeling and modification techniques. -
Biochemical Reagent
DBCO-Palmitic is a reactive biochemical reagent that functions as a click chemical under the azide-alkyne cycloaddition mechanism. This compound is particularly useful for labeling and modifying biomolecules through SPAAC reactions, facilitating the study of various biological processes. Its applications include bioconjugation methods and tracking of molecular interactions in live-cell imaging. -
Click Chemical
(R,E)-TCO-NHS Ester is a Click chemical reagent designed for the selective labeling of amine-containing compounds and biomolecules. This compound features a TCO moiety that participates in an inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-labeled molecules. Its high reactivity and specificity make it suitable for various applications in bioconjugation, chemical biology, and drug discovery. -
PEG Derivative
Biotin-PEG10-azide is a PEG derivative featuring biotin, 10 polyethylene glycol units, and an azide moiety. The biotin component facilitates stable non-covalent interactions with streptavidin, while the azide functional group allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. Additionally, the azide can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN derivatives. This reagent is suitable for diverse applications in bioconjugation, labeling, and biomolecule tracking in chemical biology research. -
Click chemistry intermediate
DBCO-Sulfo-Link-biotin TEA serves as a click chemistry intermediate featuring a dibenzocyclooctyne (DBCO) group, enabling efficient ring strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This reagent is primarily used for bioconjugation applications, facilitating the labeling of biomolecules with biotin for downstream interactions and assays. Its high specificity and reactivity make it valuable in chemical biology and protein engineering studies. -
Azide
4-Hydroxynonenal alkyne is a click chemical reagent that features alkynes and targets azides for bioorthogonal labeling. This compound induces heme oxygenase activity and promotes apoptosis in colon cancer (RKO) cells, making it a valuable tool for investigating oxidative stress and related cellular processes. Its applications extend to studying lipid peroxidation and the mechanism of action in cancer research. -
Biotinylation Agent
Biotin-XX hydrazide is a carbonyl-reactive biotinylation agent designed to facilitate the conjugation of biotin to various biomolecules. Featuring two aminohexanoic acid spacers, this reagent enhances avidin-binding efficiency, making it an effective tool for a wide range of research applications, including protein labeling and immobilization studies. Its utility is critical for assays that require precise detection and quantification of biotinylated targets. -
Biochemical Assay Reagent
Desthiobiotin-PEG4-alkyne is a biotinylated biochemical reagent designed for use in click chemistry applications. This compound enables the selective labeling and enrichment of specific tRNAs, facilitating the study of tRNA dynamics and interactions. It is a valuable tool for researchers exploring RNA biology and related biochemical pathways. -
PEG Derivative
Cholesterol-PEG3-azide is a PEG derivative that incorporates cholesterol, three polyethylene glycol (PEG) units, and an azide moiety. This compound participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with entities bearing DBCO or BCN groups. It is valuable for bioconjugation applications, including the development of lipidated probes and drug delivery systems within biological research. -
Sphingosine Alkyne
Sphingosine (d18:1) alkyne is an alkyne-modified sphingosine derivative designed for applications in click chemistry. This compound facilitates the study of sphingolipid metabolism and signaling pathways by allowing researchers to label sphingosine in cellular systems. Its structure enables selective and efficient conjugation with various biomolecules, expanding the toolkit for investigating lipid interactions and functions in biological research. -
cyclo(RGDfK) Derivative
DBCO-cyclo(RGDfK) is a derivative of the cyclo(RGDfK) peptide that incorporates a DBCO (dibenzocyclooctyne) moiety. This compound functions as a clickable ligand for targeting integrins, facilitating the study of cell adhesion and migration. Its unique structure enables applications in bioconjugation and drug delivery systems, particularly in cancer research and tissue engineering. -
Click Chemistry Reagent
TCO-PEG3-acid is a click chemistry reagent featuring a trans-cyclooctene (TCO) moiety that participates in inverse electron demand Diels-Alder (iEDDA) reactions with tetrazine-containing molecules. This compound is applicable in bioconjugation and labeling studies, facilitating the development of targeted therapies and imaging agents. Its utility in the rapid and selective formation of covalent bonds makes it a valuable tool in chemical biology and biomedical research. -
Biochemical Assay Reagents
DBCO-propargyl-PEG5-TFP ester is an amine-reactive labeling reagent featuring a DBCO group. This compound is designed for bioconjugation applications, specifically enabling strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing biomolecules. Its versatile chemistry makes it suitable for a variety of biochemical assays and targeted labeling studies in molecular biology and biochemistry. -
Click Chemistry Compound
(3aS,4S,6aR)-Biotin-PEG4-Alkyne is a biotinylation reagent featuring an alkyne functional group, designed for applications in click chemistry. This compound facilitates the conjugation of azides through a copper-catalyzed click reaction, enabling the labeling of biomolecules with biotin. The resulting biotinylated constructs can effectively interact with avidin or streptavidin, making this reagent valuable for purification and detection assays in biochemical research. -
Biochemical Assay Reagent
Biotin-PEG8-azide is a chemical reagent designed for click chemistry applications, enabling the biotinylation of macromolecules. This compound facilitates the selective labeling of proteins, nucleic acids, and other biomolecules, allowing for enhanced detection and purification in biochemical assays. Its utility in diverse research applications includes studying protein-protein interactions and tracing biological pathways. -
Click Chemistry Compound
Biotin-PEG8-Alkyne is a click chemistry compound designed for efficient bioconjugation through azide-alkyne cycloaddition. This reagent facilitates the direct labeling of biomolecules and can be utilized in various applications, including protein tagging, cellular imaging, and the development of bioconjugates. Its biotinylated structure enhances binding affinity to streptavidin, making it a powerful tool for studying protein interactions and tracking biomolecules in complex biological systems. -
Biochemical Assay Reagent
Biotin-PEG2-alkyne is a biochemical assay reagent designed to facilitate affinity-based applications. This compound features a biotin group for effective binding in assays such as pull-down assays, combined with a terminal alkyne that allows for copper (I) catalyzed click chemistry with azides. It is suitable for various research applications, including protein labeling and tracking. -
Glycobiology
2-Acetamido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-β-D-glucopyranosyl azide is a specialized biochemical reagent targeting glycobiology. This compound is instrumental in the study of glycan structure and function, facilitating research into carbohydrate chemistry, glycan synthesis and degradation, and protein-glycan interactions. Its applications are pivotal in advancing understanding in biomedicine and biotechnology, contributing to the exploration of the roles glycans play in biological systems. -
Cross-linking Agent
Mal-b-Lys(mal)-PEG4-amide-PEG3-azide is a versatile cross-linking agent that facilitates the conjugation of antibodies. This compound is particularly useful for the synthesis of antibody-drug conjugates (ADCs), enabling targeted delivery of therapeutic agents. Its unique structure allows for effective and selective cross-linking, making it valuable in various biochemical and biophysical research applications. -
Biochemical Assay Reagent
DBCO-NHCO-C5-O-phenylethenesulfonyl fluoride is a versatile DBCO-containing linker designed for efficient bioconjugation. This reagent enables precise attachment of biomolecules and facilitates drug delivery applications. Its unique chemical structure allows for site-specific labeling in biochemical assays, making it a valuable tool in various research settings focused on protein interactions and cellular mechanisms. -
Sugar
2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide is a glycosyl azide derivative targeting glycobiology applications. This compound serves as a versatile substrate for the investigation of enzyme activity, facilitating research in carbohydrate biochemistry. Its high purity of 98% ensures reliable results in experimental settings. -
Lipid
16:0 DBCO PE ammonium is a phosphatidylethanolamine (PE) derivative featuring a reactive dibenzocyclooctyne (DBCO) moiety. This functionalized lipid serves as a valuable click chemistry reagent, facilitating strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. It is ideally suited for applications in bioconjugation, lipid modification, and the development of lipid-based delivery systems in biochemical research. -
Biotin Derivative
Biotin N-(bromoacetyl)hydrazide is a biotin derivative that serves as a valuable tool for labeling and detecting biomolecules. This compound is instrumental in bioconjugation studies where it can facilitate the attachment of biotin to proteins, peptides, or other macromolecules. Its applications extend to various research fields, including proteomics, cellular imaging, and the development of biotin-affinity purification methods. -
Biochemical Assay Reagent
β-D-Glucopyranosyl azide, 2-(acetylamino)-2-deoxy, 3,4,6-triacetate is a biochemical assay reagent that serves as a versatile tool for glycosylation studies. It enables the exploration of glycosylation patterns and interactions in various biological systems. This compound is particularly useful in the development of glycoengineered therapeutics and for elucidating the roles of glycoconjugates in cellular processes. -
Biochemical Assay Reagent
Azide-C3-NHCO-C3-NHS ester serves as a versatile linker in biochemical assays, facilitating efficient and specific ligation through click chemistry. This reagent is ideal for applications in protein labeling, biomolecule modification, and the development of complex biochemical systems. Its reactive nature makes it a valuable tool for researchers engaged in chemical synthesis and functionalization studies. -
Biochemical Reagent
Pent-4-ynehydrazide is a biochemical reagent employed as an intermediate in organic synthesis. It serves as a valuable precursor for the synthesis of Hydrazone-DOX-Alkyne. This compound is particularly relevant in cancer research, facilitating the exploration of therapeutic applications and development of novel treatment strategies. -
Biochemical Assay Reagent
DBCO-amine TFA is a versatile biochemical assay reagent featuring a DBCO moiety linked to an amine group. The amine exhibits high reactivity with NHS esters, facilitating the formation of stable covalent bonds. This compound is widely utilized in copper-free Click Chemistry reactions, enabling efficient labeling and conjugation in various biochemical applications. -
Glycobiology
3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-α-D-glucopyranosyl azide is a specialized reagent utilized in glycobiology, focusing on the study of carbohydrate structures and their biological significance. It facilitates research on glycan synthesis and recognition, contributing to the understanding of glycan-related processes in various biological systems. This compound is essential for investigating the roles of glycans in health and disease, making it a valuable tool for researchers in the fields of biomedicine and biotechnology. -
Glycobiology
Hepta-O-acetyl-β-lactosyl azide is a biochemical reagent that acts as a reliable substrate for glycosyltransferases in glycobiology research. This compound facilitates the study of glycan structure and function by enabling the synthesis and analysis of glycan-related biomolecules. Its applications extend to carbohydrate chemistry, enzymology, and the investigation of protein-glycan interactions, aiding in the understanding of the biological roles of glycans in various systems. -
Biochemical Assay Reagents
2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl azide serves as a biochemical reagent in glycobiology research. This compound facilitates the study of carbohydrate chemistry, glycan synthesis and degradation, as well as protein-glycan interactions. Its application extends to essential areas in basic research, biomedicine, and biotechnology, enabling deeper exploration of the role of glycans in biological systems. -
click chemistry reagent
PreQ1-alkyne is a click chemistry reagent featuring an alkyne functionality that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions. This compound is pivotal for bioconjugation applications, allowing for the selective labeling and modification of biomolecules containing azide groups. Its utility extends to the synthesis of complex biomolecular structures in chemical biology and materials science research. -
Endogenous Protein Marker
N-TCO-L-lysine is a non-canonical amino acid featuring a trans-cyclooctene (TCO) bioorthogonal reactive linker. This compound is engineered for the selective labeling of endogenous proteins through a bioorthogonal click reaction with SiR-Tz, facilitating site-specific incorporation. N-TCO-L-lysine is valuable for super-resolution and live-cell imaging applications, enabling researchers to study the dynamics and localization of proteins in their native environments. -
Click Chemical Reagent
Biotin-azide (N-(3-Azidopropyl)biotinamide) serves as a versatile click chemical reagent featuring a terminal azide moiety. This compound facilitates the synthesis of biotinylated conjugates through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, Biotin-azide is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclo[6.1.0]nonyne (BCN) functional groups. Its applications span various fields, including bioconjugation and visualization studies in chemical biology. -
APEX2 Probe
Alkyne-phenol is a clickable probe specifically designed for use with ascorbate peroxidase 2 (APEX2). This reagent significantly enhances APEX-labeling efficiency in intact yeast cells due to its improved permeability through cell walls compared to traditional APEX2 substrates. Alkyne-phenol aids in the identification of APEX-labeling sites, providing clear insights into the membrane topology of mitochondrial proteins. Additionally, it features an alkyne group that allows for copper-catalyzed azide-alkyne cycloaddition (CuAAc), making it a versatile tool for click chemistry applications in biological research. -
Click Chemistry Reagent
DBCO-amine is a click chemistry reagent featuring a dibenzocyclooctyne (DBCO) group, which facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This compound is instrumental in the synthesis of antibody-drug conjugates (ADCs), providing a targeted approach for delivering therapeutics. Its utility extends to various applications in chemical biology, including bioconjugation and the development of precision medicine strategies. -
Click Chemistry Reagent
DBCO-acid is a click chemistry reagent that features a DBCO (dibenzocyclooctyne) moiety, enabling strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing compounds. This reagent is essential for the synthesis of antibody-drug conjugate (ADC) linkers, such as DBCO-NHS ester and DBCO-PEG-MMAE. DBCO-acid facilitates the formation of agent-linker conjugates, providing researchers with robust tools for bioconjugation applications in drug delivery and molecular labeling. -
Biotinylation Reagent
DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin conjugate designed for biotinylation applications. This reagent facilitates the introduction of a biotin moiety to azide-tagged biomolecules through copper-free strain-promoted alkyne-azide cycloaddition (SPAAC). DBCO-PEG4-Biotin is particularly valuable in applications involving protein labeling, detection, and purification, enhancing the study of biomolecular interactions and cellular processes. Its PEG components improve solubility and stability, making it an essential tool in chemical biology research. -
Biochemical Assay Reagent
Carboxyl diazirine alkyne is a protein cross-linking compound that enables the study of protein interactions and modifications. This reagent is particularly valuable in biochemical assays focused on the inhibition and labeling of the FTO protein using fluorescein derivatives, facilitating advanced research in metabolism and epigenetics. Its unique properties allow for covalent bonding, thereby enhancing the specificity and sensitivity of detection methods in various biological applications. -
Click Chemistry Agent
endo-BCN-NHS carbonate is a versatile click chemistry agent that modifies elastin-like proteins (ELPs) by introducing BCN groups through reaction with lysine residues. This compound facilitates the formation of hydrogels via the strain-promoted azide-alkyne cycloaddition (SPAAC) mechanism, enabling enhanced structural integrity in biomaterials. endo-BCN-NHS carbonate is primarily utilized in cell encapsulation studies, supporting advancements in tissue engineering and regenerative medicine research. -
Click Chemistry Reagent
Tetrazine-Amine monohydrochloride is a click chemistry reagent featuring a tetrazine group, which facilitates covalent labeling of living cells via inverse electron demand Diels-Alder (iEDDA) reactions with TCO-containing molecules. This compound enables precise bioconjugation in various biological studies, making it an essential tool for researchers focusing on protein labeling, drug delivery, and imaging applications. Its ability to promote rapid and selective reactions enhances its utility in the design of targeted therapeutics and biomolecular probes. -
BCN-TPP Probe Control
BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is an alcohol-functionalized cyclooctyne derivative that serves as a precursor for the synthesis of various bioconjugation probes, including BCN-TPP. It facilitates the construction of targeted probes through coupling reactions with carboxyl-containing compounds, such as TPP-COOH. Additionally, BCN-OH functions as a control reagent for experiments involving BCN-TPP, providing a valuable tool for researchers in chemical biology and bioconjugation studies. -
Cross-Linked Peptide
Azide-A-DSBSO crosslinker is a homobifunctional, azide-labeled crosslinking reagent that targets lysine residues through an NHS ester reaction. This membrane-permeable and acid-cleavable compound is particularly useful in cross-linking mass spectrometry (XL-MS) to investigate protein-protein interactions. Its mass spectrometry-cleavable properties enable efficient analysis of cross-linked complexes, facilitating deeper insights into protein dynamics and interactions in biological systems. -
Tetrazines
Methyltetrazine-amine is a tetrazine compound that enables site-specific dual functionalization of bioconjugates. This reagent facilitates the precise modification of biomolecules, making it valuable in the development of targeted therapeutics and imaging agents. Its unique reactivity allows for selective labeling and conjugation, supporting various applications in chemical biology and drug development. -
Click Chemistry Reagent
Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is a click chemistry reagent featuring an azide functional group. This compound facilitates the efficient and specific labeling of biomolecules, including nucleic acids, lipids, and proteins, making it valuable in various research applications. Its properties allow for high-yield reactions and straightforward conjugation processes, enabling advancements in drug development, bioconjugation, and materials science. -
Long Chain Protein Modification Reagent
Biotin LC hydrazide is a long chain protein modification reagent that specifically targets periodate-oxidized glycoproteins. It facilitates the biotinylation of these proteins, enhancing their detection and isolation in various biological assays. This reagent is widely used in research applications that require the study of glycoprotein functionality and interactions. -
APEX2 Probe
Tyramide alkyne serves as a novel labeling substrate for APEX2 probes, effectively facilitating the detection and enrichment of specific biomolecules. It can be conjugated to various detection moieties through a Copper-catalyzed Azide/Alkyne Cycloaddition (CuAAC) "click" reaction. This compound is instrumental in enhancing spatial resolution in biological imaging and is utilized in advanced proteomics and cellular studies. -
Tetrazines Compound
Methyltetrazine-amine hydrochloride is a tetrazine compound that serves as a versatile reactive moiety for site-specific dual functionalization of bioconjugates. This reagent facilitates efficient labeling and immobilization strategies in chemical biology applications. It can be effectively utilized during protein precipitation in experiments employing trans-cyclooctene, making it a valuable tool for researchers focusing on conjugation methodologies and biomolecular studies.
