Catalog No.
Product Name
Application
Product Information
Citations
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DBCO Iridium Catalyst
DBCO Iridium Catalyst functions as a powerful tool for in situ labeling and imaging of biomolecules, including proteins and nucleic acids, in living organisms. Its unique DBCO labeling capability enhances the specificity and efficiency of targeted drug delivery systems. This catalyst is essential for researchers investigating biomolecular interactions and developing advanced imaging techniques in biological systems. -
Azide
Cholesteryl-Teg azide is a cholesterol-modified azide that facilitates bioconjugation reactions. It serves as a valuable ligand for tagging and modifying biomolecules, particularly RNA strands, enabling advanced studies in molecular biology and drug development. Its properties support research in areas such as gene delivery and the synthesis of cholesterol-based therapeutics. -
Click Chemistry Agent
exo-BCN-NHS carbonate is a highly reactive Click Chemistry agent featuring a BCN (bicyclononyne) moiety. It facilitates strain-promoted alkyne-azide cycloaddition (SPAAC), enabling efficient coupling with azide-containing compounds. This reagent is particularly useful for bioconjugation applications, allowing researchers to label biomolecules or proteins selectively and efficiently, enhancing the study of biological systems and interactions. -
Glycoconjugates Label
Biocytin hydrazide is a selective labeling reagent designed for targeting sialic acids, galactose, and other sugars in glycoconjugates through avidin-biotin technology. This compound facilitates the study of glycan structures and their biological roles, aiding in research applications such as glycoprotein analysis, cell surface marker identification, and carbohydrate-protein interactions. Its specificity makes it an invaluable tool for investigating complex carbohydrate moieties in various biological systems. -
Lipid
18:1 DBCO PE ammonium is a functionalized lipid that features a reactive dibenzocyclooctyne (DBCO) moiety and phosphatidylethanolamine (PE) backbone. This reagent is utilized in click chemistry applications, particularly in strain-promoted alkyne-azide cycloaddition (SPAAC), allowing for efficient and bioorthogonal labeling of azide-containing molecules. Its biocompatible properties enhance its utility in various biological research applications, including targeted drug delivery and cellular imaging. -
PEG Derivative
Methyltetrazine-PEG4-amine is a PEG derivative featuring a free amine and a methyltetrazine moiety. As a versatile click chemistry reagent, it facilitates the inverse electron demand Diels-Alder (iEDDA) reaction with trans-cyclooctene (TCO) containing compounds. This reagent can be employed in bioconjugation strategies, enabling the development of targeted therapeutics and imaging agents in chemical biology research. -
Biochemical Assay Reagent
Methyltetrazine-PEG5-sulfo-NHS ester sodium is a versatile biochemical assay reagent that functions primarily as a crosslinker for biomolecules. This compound enables efficient conjugation with amine-containing molecules, facilitating the study of protein interactions and modifications. Its solubility in aqueous environments increases its applicability in various biological assays and research applications, making it a valuable tool in chemical biology and bioconjugation techniques. -
Biochemical Assay Reagent
3-Chlorophenylacetylhydrazide functions as a biochemical assay reagent, essential for various life science research applications. This compound is utilized as a biological material, facilitating the study of hydrazine derivatives and their interactions in biochemical assays. Its properties make it valuable for exploring enzymatic activities and metabolic processes in cellular systems. -
Biochemical Assay Reagent
2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide is a click chemistry reagent featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing compounds, such as DBCO and BCN. This compound serves as a valuable biochemical assay reagent in various life science research applications, particularly in glycosylation studies and bioconjugation. Its stable acetylated form enhances solubility and reactivity, making it an effective tool for the synthesis of complex biomolecules and labeled substrates. -
PEG Derivative
Azide-PEG4-Desthiobiotin is a polyethylene glycol (PEG) derivative featuring an azide group and desthiobiotin. This reagent enables stable non-covalent interactions with streptavidin, facilitating applications in bioconjugation and biomolecular labeling. It is suitable for click chemistry, undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. -
UDP-GlcNAc Derivative
UDP-2-alkyne-GlcNAc is a derivative of UDP-GlcNAc, targeting glycosylation processes. This compound serves as a crucial tool for the remodeling of cell surface glycans, enabling researchers to study glycan structures and functions in various biological contexts. It is particularly useful in applications such as metabolic labeling and click chemistry for the visualization of glycoproteins and glycoconjugates. -
Clickable Phospholipid
16:0(Alkyne)-18:1 PE is a clickable phospholipid designed for use in click chemistry applications. This compound facilitates the conjugation of biomolecules, allowing for the study of lipid interactions and cellular uptake dynamics. Its unique alkyne functionality enables efficient labeling and tracking of phospholipid structures in various biological systems, making it a valuable tool for researchers in lipidomics and membrane biology. -
Glycobiology
2-Acetamido-2-deoxy-β-D-glucopyranosyl azide is a biochemical reagent utilized in glycobiology to explore glycan structures and functions. It plays a critical role in studying carbohydrate chemistry, enzymatic processes involved in glycan formation and degradation, and protein-glycan interactions. This compound supports various research applications within basic biological research, biomedicine, and biotechnological advancements. -
Click Chemistry
4-Oxo-2-Nonenal Alkyne is a functionalized lipid electrophile designed for click chemistry applications. It facilitates the conjugation to exosomes through the reaction of amino and aldehyde groups. This reagent is particularly useful for the determination and characterization of tumor-derived exosomes in various biological research settings. -
Linker
DOTA-PEG4-alkyne is a bifunctional linker designed for efficient conjugation with radionuclides. It facilitates the creation of radiolabeled biomolecules, enabling precise imaging and therapeutic applications in molecular biology and nuclear medicine. Its PEGylated structure enhances solubility and biocompatibility, making it suitable for various research applications, including drug delivery and targeted therapy. -
Biochemical Reagent
11-Maleimidoundecanoic acid hydrazide is a biochemical reagent characterized by its maleimide group, which facilitates selective covalent conjugation to thiol-containing biomolecules. This compound is primarily utilized in bioconjugation applications, enabling the development of targeted therapeutics and diagnostic tools. Its ability to form stable linkages with proteins and peptides makes it a valuable resource for researchers studying protein interactions and creating antibody conjugates. -
PEG Derivative
Endo-BCN-PEG2-Biotin is a PEG derivative featuring a bicyclo[6.1.0]nonyne (BCN) group that enables efficient clicking with azide-modified compounds. Its terminal carboxylic acid group facilitates reactivity with various functional groups, including amino acids, activated NHS esters, and carbonyls, enhancing conjugation versatility. This reagent is valuable for bioconjugation applications, such as protein labeling and drug delivery, supporting studies in chemical biology and therapeutics. -
Biochemical Assay Reagent
Endo-BCN CE-phosphoramidite is a highly reactive cyclooctyne utilized in copper-free click chemistry. Its unique reactivity allows for efficient strain-promoted azide-alkyne cycloaddition (SPAAC) and inverse electron demand Diels-Alder reactions (IEDDA) with azides and tetrazines, respectively. This chemical reagent is ideal for a variety of biochemical assays, enabling bioconjugation and labeling applications in chemical biology and drug development research. -
Click Chemistry Reagent
Sulfo-DBCO-NHS ester is a click chemistry reagent featuring an azide group and a DBCO moiety, which facilitates copper-free Click Chemistry reactions through its strain-promoted mechanism. This reagent exhibits high reactivity with amino acids and other molecules possessing amino groups via the NHS ester linkage, making it valuable for bioconjugation and labeling applications in chemical biology. Its ability to enable precise and efficient conjugation makes it suitable for a variety of research applications, including the development of therapeutics and diagnostics. -
Lipid
C16:0(Alkyne) L-carnitine is an acyl carnitine lipid that features a terminal alkyne group, serving as a valuable tool for click chemistry applications. This reagent facilitates specific reactions with azide-containing compounds in the presence of a copper catalyst, enabling efficient linkage in various biochemical studies. Its unique structure allows for functionalization and the investigation of lipid-related biological processes, making it suitable for research in cellular metabolism and lipid signaling. -
Lipid
DSPE-PEG8 DBCO is a click chemistry reagent featuring a DBCO moiety that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This reagent is pivotal for the preparation of lipid nanoparticles, enhancing drug delivery systems through novel bioconjugation strategies. Its application in biochemistry and nanotechnology makes it a valuable tool for researchers focused on developing targeted therapy and RNA delivery systems. -
Lipid
16:0(Alkyne)-18:1 PC is a clickable phospholipid that enables the study of lipid metabolism and cellular membrane dynamics. This compound serves as a versatile tool for lipid labeling in biological research, facilitating the investigation of membrane-associated processes. It is particularly useful in studies involving lipid droplet formation, membrane trafficking, and the role of phospholipids in cell signaling pathways. -
Biochemical Assay Reagent
TCO-PEG4-maleimide is a click chemistry building block designed for biochemical assays, featuring a trans-cyclooctene (TCO) moiety and a maleimide group. The maleimide moiety exhibits high reactivity with thiol groups, facilitating the formation of stable covalent bonds. This compound is particularly valuable in applications involving 3rd generation click chemistry, where the TCO moiety interacts efficiently with tetrazine derivatives, enabling versatile labeling and tagging strategies in biochemical research. -
Biochemical Assay Reagent
Azide-PEG5-Ms is a PEG-based linker designed for use in biochemical assays, featuring an azide group that undergoes Click Chemistry with BCN, DBCO, and alkynes. The mesyl group serves as an effective leaving group for nucleophilic substitution reactions, enhancing the versatility of this reagent. The polyethylene glycol (PEG) spacer provides improved water solubility, making it suitable for a variety of biological applications, including bioconjugation and drug delivery studies. -
Biochemical Assay Reagent
27-Alkyne cholesterol is a modified lipid featuring an omega-terminal alkyne, enabling its application as a biochemical assay reagent. This compound participates in click chemistry with azide-containing reagents in the presence of copper catalysts, facilitating highly specific linking reactions. As a versatile tool for investigating cellular cholesterol metabolism and localization, 27-alkyne cholesterol supports various detection methods, including mass spectrometry and fluorescence microscopy. Its sensitive and user-friendly properties make it ideal for diverse research applications in lipid biology. -
Biochemical Assay Reagent
Tco-PEG2-Tco is a bifunctional reagent featuring TCO groups at both termini, which engage in selective and efficient reactions with tetrazine. The inclusion of a hydrophilic PEG linker enhances the solubility of the compound in aqueous environments, making it suitable for various biochemical assays. This reagent is ideal for applications requiring bioconjugation or labeling of biomolecules in research studies. -
For Oligo-Nucleotides Synthesis
Alkyne Phosphoramidite, 5'-terminal is a specialized reagent designed for the synthesis of oligo-nucleotides. This compound enables the incorporation of alkyne groups at the 5' terminus, facilitating subsequent functionalization and applications in bioconjugation strategies. It is invaluable for researchers focused on nucleic acid chemistry and related biotechnological applications. -
Biochemical Assay Reagent
Azido-PEG1-hydrazide hydrochloride is a bifunctional polyethylene glycol linker featuring both azide and hydrazide groups. The azide portion facilitates reactions with alkyne, BCN, and DBCO through Click Chemistry, allowing the formation of stable triazole linkages. Meanwhile, the hydrazine moiety can react with aldehydes to produce semi-permanent hydrazone bonds. This reagent is valuable for biochemical assays and in the development of bioconjugates, enhancing the versatility of molecular modifications in research applications. -
Click Chemical
Endo-BCN-L-Lysine is a Click Amino Acid designed for use in the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. Its unique BCN group enables strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing partners, facilitating efficient and selective linking in complex molecular assemblies. This reagent is particularly valuable in chemical biology research, allowing for the development of targeted therapeutics and innovative protein degradation strategies. -
Biochemical Assay Reagent
Trivalent GalNAc-DBCO is a versatile biochemical assay reagent designed for efficient oligonucleotide coupling. It facilitates the bioconjugation of GalNAc moieties to oligonucleotides, enhancing targeting and delivery capabilities in nucleic acid research. This compound is particularly useful in developing targeted therapeutic strategies and studying oligonucleotide interactions within biological systems. -
Click Amino Acid
(2E)-TCO-PNB ester functions as a Click Amino Acid and serves as a versatile linker for the synthesis of PROTAC molecules. Its unique TCO group can participate in an inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-containing compounds, facilitating efficient conjugation in bioconjugation strategies. This reagent is suitable for applications in chemical biology, enabling the development of targeted therapeutics and advanced biomolecular constructs. -
Crosslinking Agent
Oxalyldihydrazide is a crosslinking agent that effectively captures carbonylated proteins, making it an essential tool in proteomics research. Its ability to form stable linkages allows for the precise analysis of protein modifications on microchips, facilitating the study of protein interactions and functions. Researchers utilize oxalyldihydrazide to enhance the detection and characterization of biomolecules in diverse applications, including disease biomarker discovery and cellular pathway analysis. -
Amine Reaction Reagent
TCO-PNB ester is an amine-reactive building block designed for the modification of amine-containing molecules. It features a strained trans-cyclooctene (TCO) group that participates in an inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-containing compounds. This reagent is valuable for applications in bioconjugation, enabling precise labeling and modification of biomolecules for use in various biochemical studies and therapeutic developments. -
Biochemical Assay Reagent
TAMRA alkyne, 5-isomer is an alkyne derivative of the fluorescent dye TAMRA, primarily used as a biochemical assay reagent. It enables the enrichment, in-gel fluorescence detection, and identification of O-GlcNAc-modified proteins. This compound participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules and is also reactive in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it valuable for bioconjugation applications in protein labeling and visualization. -
Biochemical Assay Reagent
DBCO-Tetraacetyl mannosamine is a click chemistry reagent featuring a DBCO moiety that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. This compound is primarily employed in biochemical assays for the modification of glycoproteins and cell surface molecules, enabling applications in biomarker discovery and purification. Furthermore, it serves as a drug carrier in controlled release systems, making it a valuable tool for advancing research in bioconjugation and drug delivery mechanisms. -
PEG Derivative
Methyltetrazine-PEG4-amine hydrochloride is a PEG derivative characterized by the presence of a free amine and a methyltetrazine moiety. This compound serves as a versatile click chemistry reagent, capable of undergoing an inverse electron demand Diels-Alder reaction (iEDDA) with trans-cyclooctene (TCO)-containing molecules. Methyltetrazine-PEG4-amine hydrochloride is valuable in biological research for applications such as bioconjugation, drug delivery, and imaging studies, facilitating the development of targeted therapies and diagnostic tools. -
Biochemical Reagent
DSPE-PEG-DBCO ammonium is a biochemical reagent that facilitates copper-free click chemistry via strain-promoted alkyne-azide cycloaddition (SPAAC) with azido-functionalized peptide ligands. This compound is pivotal in drug delivery and nanoparticle research, enabling precise biomolecule conjugation and enhancing therapeutic efficacy. Its unique properties make it suitable for various applications in bioconjugation and nanomedicine. -
Benzothiadiazine Diuretic
Cyclopenthiazide is a benzothiadiazine diuretic that acts by inhibiting the reabsorption of sodium chloride and water in the distal renal tubules. This mechanism leads to increased renal excretion and antihypertensive effects. It is commonly utilized in research to study diuretic actions and their impact on blood pressure regulation. -
Non-natural Amino Acid
(Rac)-Azide-phenylalanine is a non-natural amino acid featuring an azide functional group, allowing for selective incorporation into proteins for labeling purposes. This compound serves as a valuable tool in click chemistry, participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules. Its applications extend to bioconjugation strategies, facilitating the study of protein interactions and dynamics in chemical biology and biochemical research. -
PROTAC Linker
5-(Biotinamido)pentylazide is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This reagent features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynes. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN moieties, making it a valuable tool for chemical research in targeted protein degradation and related applications. -
PROTAC Linkers
m-PEG8-azide is a PEG-based linker specifically designed for PROTAC synthesis. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, m-PEG8-azide is suitable for strain-promoted alkyne-azide cycloaddition (SPAAC) when used with DBCO or BCN groups. Its versatile reactivity makes it a valuable tool for researchers engaged in targeted protein degradation studies. -
PROTAC Linker
Azide-PEG3-C1-Ala is a PEG-based linker designed for PROTAC (proteolysis-targeting chimera) synthesis. This compound features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) compounds. This versatile linker is essential for studying targeted protein degradation and enhancing the efficacy of therapeutic agents. -
PROTAC Linker
Amino-PEG8-hydrazide-Boc is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). Its primary mechanism targets the recruitment of E3 ubiquitin ligases, facilitating the ubiquitination and degradation of specific proteins. This reagent is essential for developing novel therapeutic strategies aimed at modulating protein levels and has significant applications in chemical biology and drug discovery research. -
PROTAC Linkers
Methyltetrazine-PEG5-triethoxysilane is a PEG-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins to E3 ligases, thereby promoting targeted protein degradation. It serves as a crucial component in the development of novel therapeutic strategies aimed at modulating protein expression and activity in various biological systems. -
PROTAC Linkers
Propargyl-PEG3-azide is a PEG-based linker specifically designed for the synthesis of PROTACs. This compound features an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-functionalized compounds. Its versatility makes it a valuable tool in chemical biology and therapeutic research applications involving targeted protein degradation. -
PROTAC Linkers
Gly-PEG3-endo-BCN is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features a bicyclo[6.1.0]non-4-yne (BCN) moiety that enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Gly-PEG3-endo-BCN is essential for constructing bifunctional molecules, facilitating targeted protein degradation, and advancing chemical biology research applications. -
PROTAC Linker
PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). Featuring a tetrazine moiety, this compound facilitates selective interactions through inverse electron demand Diels-Alder (iEDDA) reactions with TCO-containing partners. Its unique chemical structure allows for efficient conjugation and modularity in the design of targeted protein degradation experiments, making it a valuable tool in chemical biology and therapeutic development research. -
PROTAC Linker
endo-BCN-PEG2-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound features a bicyclo[6.1.0]nonyne (BCN) moiety, facilitating strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing substrates. Its application in PROTAC development allows for targeted protein degradation, making it a valuable tool in chemical biology and drug discovery. -
PROTAC linker
N-methyl-N'-(azide-PEG3)-Cy3 is a PEG-based linker designed for use in the synthesis of PROTACs, facilitating targeted protein degradation. This compound acts as a click chemistry reagent due to the presence of an azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it a versatile tool in chemical biology and medicinal chemistry research applications. -
PROTAC linker
N-(azide-PEG3)-N'-(Amine-C3-Amide-PEG4)-Cy5 is a PEG-based linker designed for the synthesis of PROTACs, functioning primarily through the azide group. This compound participates in click chemistry, specifically through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It is also capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized entities, making it a versatile tool for targeted protein degradation studies and other bioconjugation applications.
