Catalog No.
Product Name
Application
Product Information
Citations
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Biochemical Assay Reagent
4-Azide-TFP-amide-PEG4-acid is a biochemical assay reagent designed for efficient conjugation reactions. Featuring an aryl azide that can be photo-activated under UV light (250 to 350 nm), it facilitates the covalent attachment to various biomolecules. The inclusion of a PEG spacer enhances aqueous solubility and minimizes steric hindrance during ligation, while the carboxylic acid moiety allows for amine reactions in the presence of an activator to generate stable amide bonds. This reagent is suitable for applications in bioconjugation chemistry and the development of novel biosensors. -
Biochemical Assay Reagent
6-(Biotinamido)hexylazide is a click chemistry biotinylation reagent that targets alkynes to form stable triazole linkages. This compound is essential for various biochemical assays, enabling efficient labeling of biomolecules for detection and isolation. Its versatility makes it suitable for applications in proteomics, cell biology, and drug discovery, facilitating the study of protein interactions and biological pathways. -
Biochemical Assay Reagent
TCO-PEG2-acid is a click chemistry linker that features a trans-cyclooctene (TCO) moiety and a terminal carboxylic acid, enabling efficient interaction with primary amine groups when activated by agents such as EDC. This reagent exhibits high reactivity with tetrazine through an inverse electron demand Diels-Alder (IEDDA) reaction, facilitating the formation of stable conjugates. The inclusion of a hydrophilic polyethylene glycol (PEG) spacer enhances solubility in aqueous environments, making it suitable for biochemical assays and various bioconjugation applications. -
Biochemical Assay Reagent
Methyltetrazine-amido-Tri-(acid-PEG1-ethoxymethyl)-methane is a versatile click chemistry PEG reagent featuring three carboxylic acid groups and a methyltetrazine moiety. This compound facilitates the formation of stable covalent bonds with TCO-containing compounds through a rapid inverse-electron demand Diels-Alder cycloaddition, notable for its exceptional selectivity and lack of reliance on copper catalysts or elevated temperatures. Additionally, the terminal carboxylic acid can react with primary amine groups using coupling agents such as EDC or HATU to generate stable amide bonds, making it suitable for various biochemical assay applications. -
Biochemical Assay Reagent
4-Azide-TFP-amide-SS-propionic acid is a biochemical assay reagent featuring an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide undergoes photo-activation with UV light (250 to 350 nm), facilitating conjugation with various biomolecules. The carboxylic acid is reactive towards amines in the presence of an activator, allowing for the formation of stable amide bonds. The associated disulfide bond can be selectively cleaved using reducing agents, making this compound valuable for applications in protein labeling and conjugation studies. -
Biochemical Assay Reagent
Methyltetrazine-PEG11-DBCO is a TCO-reactive reagent featuring a DBCO group and a hydrophilic PEG spacer. This compound enables the efficient conversion of azide-containing peptides or proteins into tetrazine-modified analogs without the need for catalysts or auxiliary reagents. The DBCO moiety is particularly beneficial for facilitating copper-free Click Chemistry reactions, making this reagent valuable for biochemical assays and labeling applications in chemical biology and therapeutic research. -
Biochemical Assay Reagent
TCO-PEG4-TFP Ester is an amine-reactive labeling reagent, primarily targeting amine-containing biopolymers such as proteins and antibodies. The inclusion of 2,3,5,6-tetrafluorophenol (TFP) provides enhanced hydrolytic stability in aqueous environments, leading to more efficient and reproducible labeling processes. TFP esters react with primary amines to form covalent amide bonds at rates comparable to NHS esters, making this reagent valuable for biochemical assays and various protein modification applications. -
Strained Cycloalkyne-based Probe
BCN-E-BCN is a strained cycloalkyne-based probe that selectively targets sulfenic acid groups, marking an essential intermediate in protein oxidation. This compound effectively detects protein sulfenylation by remaining inert to other oxidative states, including free thiols and sulfinic or sulfonic acid groups. Its design enables efficient conjugation with azide-bearing tags via copper-free click chemistry, enhancing detection sensitivity and reaction kinetics. BCN-E-BCN serves as a valuable tool for advancing research into protein oxidation and its biological implications. -
Ester Product
13(S)-Hydroxy-9(Z),11(E)-octadecadiene-(2-biotinyl)hydrazide is an ester product that acts as a fatty acid derivative. This compound is utilized in various biochemical assays and research applications focusing on lipid metabolism and signaling pathways. Its biotinylation allows for specific labeling and detection in cellular experiments, facilitating studies in cell biology and biochemistry. -
Biochemical Assay Reagent
Alkyne sphinganine is a biochemical assay reagent that features a terminal alkyne group, enabling the selective tagging of protein-lipid complexes through click chemistry. This compound facilitates a highly specific reaction with azide-containing reagents in the presence of a copper catalyst, allowing for the visualization and proteomic profiling of protein-sphingolipid interactions in living cells. Its application in metabolic labeling contributes significantly to the understanding of lipid biology and cellular dynamics. -
Biochemical Assay Reagents
Pentanehydrazide, also known as valeric acid hydrazide, functions as an effective alkylating agent in biochemical assays. It participates in copper-catalyzed oxidative cyclization reactions of N-arylacrylamides and is capable of facilitating tandem acylation processes. Its chemical properties make it a valuable tool in synthetic organic chemistry and various research applications. -
Biochemical Assay Reagent
5-(Tetrahydro-2H-pyran-2-yloxy)pent-3-yn-1-peg4-azide is an azide-functionalized reagent designed for biochemical assays and bioorthogonal reactions. This compound facilitates click chemistry applications, enabling efficient labeling and tracking of biomolecules. Its unique structure allows for versatile applications in chemical biology and bioconjugation studies, making it ideal for researchers investigating molecular interactions and biological pathways. -
Phosphorous Amide Monomer
Alkyne amidite, hydroxyprolinol is a phosphorous amide monomer designed for oligonucleotide synthesis. This reagent facilitates the incorporation of alkyne functionalities into nucleic acid structures, enabling various applications in bioconjugation and probe development. Its unique properties make it a valuable tool for researchers focused on nucleic acid chemistry and related fields. -
Biochemical Assay Reagent
DBCO-PEG6-NH-Boc is a biochemical assay reagent featuring a dibenzocyclooctyne (DBCO) functional group attached to a Boc-protected amine via a polyethylene glycol (PEG) linker. The DBCO group enables efficient copper-free click chemistry reactions with azides, facilitating bioconjugation in a range of biological contexts. The hydrophilic PEG linker enhances the compound’s water solubility, making it suitable for diverse applications in biomolecular research and drug development. The Boc protecting group can be easily removed under acidic conditions, allowing for versatile modifications in experimental setups. -
Click Chemistry Agent
Losartan azide is a click chemistry agent featuring an azide functional group, serving as a synthetic intermediate in the development of angiotensin AT1 receptor-targeted renal imaging probes. It is primarily employed in the synthesis of [18F]fluoropyridine-losartan for positron emission tomography (PET) imaging applications. This reagent is useful in the investigation of renal function and cardiovascular diseases, facilitating advanced research in diagnostic imaging. -
Biochemical Assay Reagent
Azido-PEG12-azide is a biochemically active PEG-based linker featuring two azide groups. This compound facilitates Click Chemistry reactions with alkynes, BCN, or DBCO, resulting in the formation of a stable triazole linkage. It is particularly useful in applications involving bioconjugation, labeling, and the synthesis of complex biomolecules for various research purposes. -
Biochemical Assay Reagent
Alkyne maleimide is a bifunctional linker reagent characterized by a terminal maleimide group and a propargyl group. The maleimide group effectively reacts with thiol groups to form stable covalent bonds, facilitating the conjugation of biomolecules containing thiols. Additionally, the propargyl group enables specific labeling of azide-containing biomolecules through Click Chemistry. This reagent is widely used in biochemical assays and protein labeling applications. -
Biochemical Assay Reagent
N-(TCO)-N-bis(PEG4-acid) is a versatile click chemistry reagent featuring a terminal trans-cyclooctene (TCO) group and two terminal carboxylic acid moieties. This compound facilitates the formation of stable covalent bonds through inverse-electron demand Diels-Alder cycloaddition with tetrazine-containing molecules, representing one of the fastest and most selective bioorthogonal reactions. The carboxylic acids can also efficiently react with primary amino groups in the presence of common coupling activators, such as EDC or HATU, making this reagent suitable for various biochemical assays and labeling applications in research settings. -
Biochemical Assay Reagent
Hex-5-ynehydrazide is a bifunctional linker reagent featuring a terminal hydrazide group and a propargyl moiety. The hydrazide group facilitates the formation of a semi-permanent hydrazone bond through reaction with aldehydes, enabling stable conjugation in biochemical assays. Additionally, the propargyl group is suitable for selective coupling to azide-containing biomolecules via Click Chemistry, making it a valuable tool for various research applications in chemical biology and bioconjugation studies. -
Biochemical Assay Reagent
Acid-PEG5-Amide-Tri (3-methoxypropanamide-PEG4-Azide) Methane is a branched polyethylene glycol (PEG) linker featuring a terminal carboxylic acid functionality and three terminal azide groups. Its azide moieties facilitate PEGylation through Click Chemistry, making it a valuable reagent for biochemical assays. This compound is ideal for modifying biomolecules and enhancing their solubility or bioactivity in various research applications. -
Paclitaxel Modified With DBCO
Paclitaxel-DBCO is a derivative of Paclitaxel, modified to include a dibenzocyclooctyne (DBCO) linker. This modification enhances its conjugation capabilities, making it suitable for targeted drug delivery applications. Paclitaxel-DBCO retains the cytotoxic properties of the parent compound, thereby facilitating research on its efficacy in cancer therapeutics and nanoparticle formulation studies. It serves as a valuable tool for bioconjugation and drug development in cancer research. -
Derivative of Cholesterol
19-Alkyne Cholesterol is an alkyne-modified derivative of cholesterol that serves as a valuable tool for studying cholesterol localization and subcellular distribution in cellular environments. This compound facilitates the investigation of cholesterol dynamics and its role in membrane biophysics. It is particularly useful in biochemistry and cell biology research applications, enabling insights into cholesterol-related processes and signaling pathways. -
Diuretic Agent
5-Chloro hydrochlorothiazide acts as a diuretic agent by inhibiting sodium reabsorption in the renal tubules, which leads to increased urine output. This compound is primarily utilized in research settings to study fluid regulation, electrolyte balance, and hypertension. Its efficacy in promoting diuresis makes it a valuable tool for investigating renal physiology and cardiovascular health. -
Drug Derivative
Cinnamohydrazide, a derivative of unsaturated carboxylic acids, functions as a precursor to aspartame through enzymatic amination with phenylalanine. This compound exhibits promising potential in diabetes management, as it stimulates insulin secretion, enhances pancreatic β-cell function, and inhibits hepatic gluconeogenesis. Additionally, Cinnamohydrazide promotes glucose uptake, amplifies insulin signaling pathways, delays carbohydrate digestion and glucose absorption, and reduces protein glycation and insulin fibrillation, making it a valuable tool for research in metabolic disorders. -
Oligonucleotide Modifier Containing
BCN-CE-phosphoramidite is an oligonucleotide modifier featuring a BCN (strained cyclooctyne) structure, which enables bioorthogonal reactions. This reagent is designed for efficient bioconjugation in chemical biology applications. It is particularly useful for labeling oligonucleotides with diverse probes, facilitating studies in nucleic acid research and functional assays. - Nicotinohydrazide, also known as nicotinic acid hydrazide, is a small molecular compound that serves as a hydrazine derivative. This compound is of interest in various biological research applications due to its potential to act as a precursor in the synthesis of pharmacologically active agents. It may also play a role in the study of nicotinic receptor modulation and hydrazone formation in biochemical pathways. Further investigation into its mechanisms could provide insights into its utility in drug development and therapeutic research.
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Psoralen-triethylene glycol azide
Psoralen-triethylene glycol azide is a chemical probe that targets RNA structure and conformation in living cells through selective crosslinking. This compound facilitates RNA analysis and characterization using advanced techniques such as RNA crosslinking followed by deep sequencing. Its applications extend to studies in RNA biology, enabling insights into RNA-protein interactions and RNA folding dynamics. -
Diuretic Agent
Polythiazide is a thiazide diuretic agent primarily targeting renal sodium reabsorption. It is known for its antihypertensive properties, effectively reducing blood pressure and alleviating edema. Additionally, Polythiazide exhibits phototoxicity, which may be relevant in certain research applications. Its use is common in studies related to hypertension and fluid balance regulation. -
Heterobifunctional Linker
TCO-PEG5-C2-Mal is a heterobifunctional linker designed for use in tetrazine ligation and sulfhydryl conjugation. This reagent facilitates the efficient coupling of biomolecules by enabling selective labeling and conjugation strategies. It is particularly useful in bioconjugation applications, including targeted drug delivery and the development of novel therapeutics. -
Click Chemical
(Rac)-BCN-L-Lysine is a Click Amino Acid featuring a bicyclononyne (BCN) moiety that serves as a linker in the synthesis of PROTAC (Proteolysis Targeting Chimera) molecules. This compound is designed for efficient bioconjugation through strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing partners. Its application in drug development facilitates targeted protein degradation research, advancing studies in pharmacology and chemical biology. -
Metal-organic Framework
1,2,4,5-Tetrazine-3,6-dicarboxylic acid serves as a crucial building block for metal-organic frameworks (MOFs). This compound exhibits robust coordination properties, facilitating the formation of porous structures that can be utilized in gas storage, catalysis, and sensing applications. Its unique tetrazine moieties offer potential for enhanced stability and functionality in various chemical research endeavors. -
Stable Isotope
4-Methylbenzenesulfonhydrazide-d3 is a stable isotope-labeled derivative of 4-Methylbenzenesulfonhydrazide. This compound is utilized primarily in mass spectrometry and metabolic studies, serving as a tracer in biological research. Its deuterium labeling enables enhanced quantification and tracking of biochemical reactions, making it a valuable tool in the study of hydrazine derivatives and related biological pathways. -
Stable Isotope
Adipic acid dihydrazide-d8 is a deuterium-labeled derivative of adipic acid dihydrazide, primarily serving as a stable isotope for research applications. This compound can be utilized in metabolic studies and isotopic labeling experiments to trace pathways in biological systems. Its unique isotopic signature enhances the accuracy of analytical techniques such as mass spectrometry, facilitating deeper insights into chemical reactions and biological processes. -
Stable Isotope
Semicarbazide-13C,15N2 hydrochloride is a stable isotope labeled compound featuring both 15N and 13C isotopes. It primarily serves as a precursor in the synthesis of various nitrogen-containing compounds and can be utilized in studies involving metabolic pathways and tracer experiments. Its stable isotopic labeling makes it an essential reagent for researchers investigating the mechanisms of action and metabolism of biologically relevant molecules. -
Stable Isotope
Hydroflumethiazide-13C,d2 is a stable isotope-labeled form of Hydroflumethiazide, incorporating both deuterium and carbon-13 isotopes. This compound serves as an important tool in pharmacokinetic studies and metabolic research, allowing for precise tracking of drug metabolism and distribution in biological systems. Its application extends to studies involving the pharmacological effects and mechanisms of thiazide diuretics in various physiological contexts. -
Stable Isotope
Potassium Azide-15N is a stable isotope-labeled compound primarily utilized in research involving stable isotope labeling and mass spectrometry. It serves as a valuable tool in metabolic studies, tracing nitrogen incorporation in biological systems, and advancing the understanding of azide chemistry in various applications. This compound supports research in fields such as chemical biology, metabolic profiling, and environmental studies. -
Stable Isotope
4-Hydroxybenzhydrazide-d4 is a deuterated analogue of 4-Hydroxybenzohydrazide, serving as a stable isotope labeled reagent. This compound is primarily utilized in quantitative mass spectrometry and tracing studies in various biological research applications. Its use enables enhanced sensitivity and specificity in the analysis of metabolic processes and biomolecular interactions. -
Stable Isotope
4-Benzyl-1-piperazineacetic Acid Hydrazide-d8 is a stable isotope-labeled derivative of 1-Piperazineacetic acid, 4-(phenylmethyl)-, hydrazide. This compound is primarily utilized in mass spectrometry and other analytical techniques, allowing for precise quantification and tracking of biological pathways. It serves as a valuable tool in pharmacokinetic studies, drug metabolism research, and isotopic labeling applications, facilitating enhanced understanding of complex biological systems. -
Asymmetric Unit
4-Amino-2-hydroxybenzohydrazide functions as an asymmetric unit, featuring two crystallographically independent molecules, designated A and B. This compound is of interest in structural biology and crystallography, providing insights into molecular interactions and conformational dynamics. Its unique structural characteristics make it suitable for investigations into novel synthetic pathways and pharmacological applications in drug discovery. -
Bioorthogonal Probe
Itaconate-alkyne is a bioorthogonal probe designed for quantitative and site-specific chemoproteomic profiling of itaconation in live cells. As a functional analogue of itaconate, it exhibits comparable anti-inflammatory effects while facilitating the labeling of itaconate's genuine biological targets. This reagent incorporates an alkyne group, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules, making it a valuable tool for studying metabolic processes and inflammatory responses. -
Fluorescent Dyes
ICG-DBCO is a near-infrared fluorescent dye targeting biological imaging applications. Its fluorescence emits at 813 nm upon excitation at 789 nm, making it suitable for labeling cells, biomolecules, and particles. This compound is essential for various research applications, including in vivo imaging and fluorescence microscopy, allowing for enhanced visualization of biological processes. -
Fluorescent Dye
Alexa Fluor 594 azide is a fluorescent dye modified with an azide group, functioning as a FRET acceptor. Its minimal direct absorption under 488 nm excitation ensures excellent photostability and compatibility with various donor dyes, making it suitable for single-molecule imaging applications using total internal reflection fluorescence microscopy (TIRFM). This reagent is particularly valuable for visualizing copper nanoparticle-catalyzed click reactions, facilitating detailed studies of reaction dynamics and mechanisms. -
Fluorescent Dye
FAM DBCO, 6-isomer is a fluorescent dye that incorporates a terminal dibenzocyclooctyne (DBCO) group, allowing for copper-free Click Chemistry applications. This compound exhibits high reactivity due to its strained structure, facilitating the efficient formation of covalent bonds in bioconjugation reactions. FAM DBCO can be utilized in a variety of biological applications, including cell labeling, tracking, and imaging studies. -
Fluorescent Dye
Tamra azide is a versatile, azide-terminated fluorescent dye utilized primarily in click chemistry applications. It participates in CuI-catalyzed cycloaddition reactions with alkyne-functionalized nanodiamonds, enabling stable conjugation. Once attached, Tamra azide acts as a fluorescent label, exhibiting characteristic luminescence when excited at a wavelength of 555 nm with emission at 580 nm. This compound is valuable for a variety of imaging and labeling applications in chemical biology and materials science. -
Fluorescent Dye
FAM azide, 5-isomer is a fluorescent dye commonly used in Click Chemistry for bioconjugation applications. This compound facilitates the labeling of biomolecules with minimal cytotoxicity, enhancing the visualization of cellular structures and processes. Its high fluorescence intensity makes it suitable for various applications, including live-cell imaging, biomolecule tracking, and the development of fluorescent probes in research and diagnostic assays. -
Fluorescent Dye
BP Fluor 488 DBCO is a fluorescent dye designed for use in copper-free Click Chemistry reactions, specifically targeting azide-containing biomolecules such as antibodies, proteins, and peptides. It exhibits strong fluorescent properties, with an excitation peak at 499 nm and an emission peak at 520 nm, making it suitable for applications in microscopy and flow cytometry. This dye is derived from a pure 5-sulfonated rhodamine molecule, ensuring consistent performance and minimizing lot-to-lot variability caused by isomer ratio differences. -
Fluorescent Dye
APN-Azide (3-(4-Azidophenyl)propiolonitrile) serves as a fluorescent dye, enabling selective labeling of target molecules due to its distinctive chemical structure. This compound is instrumental for bioimaging applications and the creation of molecular probes aimed at investigating various biological processes within cellular environments. Its codon-active properties enhance its utility in detailed studies of cellular and molecular dynamics. -
Fluorescent Lipid
Cyanine 5.5 DBCO chloride is a versatile click chemistry reagent featuring a cycloalkyne moiety that enables efficient, copper-free bioconjugation. This compound serves as a linker for the Cyanine 5.5 fluorophore, providing excellent stability and fast reaction kinetics. With excitation and emission wavelengths of 680 nm and 715 nm, respectively, it is ideal for applications in fluorescent imaging and labeling of lipids and biomolecules in various biological research contexts. -
Fluorescent Lipid
Cyanine 7 DBCO chloride is a fluorescent lipid reagent featuring a dibenzocyclooctyne (DBCO) group that facilitates copper-free click chemistry. This compound exhibits superior biocompatibility, rapid reaction kinetics, and stability, with an excitation/emission wavelength of 745/785 nm. It is primarily utilized in biological research for fluorescent labeling and imaging applications, enabling detailed visualization of cellular structures and processes. -
Fluorescent Dye
Cyanine 5 azide is a fluorescent dye featuring an azide functional group, primarily serving as a click chemistry reagent. This compound can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. With excitation and emission wavelengths of 633 nm and 670 nm, respectively, it is valuable for a range of biological applications, including labeling and imaging studies.
