Endo-BCN-PEG2-Biotin

Catalog No.: A92456
PEG Derivative
Endo-BCN-PEG2-Biotin is a PEG derivative featuring a bicyclo[6.1.0]nonyne (BCN) group that enables efficient clicking with azide-modified compounds. Its terminal carboxylic acid group facilitates reactivity with various functional groups, including amino acids, activated NHS esters, and carbonyls, enhancing conjugation versatility. This reagent is valuable for bioconjugation applications, such as protein labeling and drug delivery, supporting studies in chemical biology and therapeutics.
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5mg
10mg
50mg
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEndo-BCN-PEG2-Biotin is a PEG derivative featuring a bicyclo[6.1.0]nonyne (BCN) group that enables efficient clicking with azide-modified compounds. Its terminal carboxylic acid group facilitates reactivity with various functional groups, including amino acids, activated NHS esters, and carbonyls, enhancing conjugation versatility. This reagent is valuable for bioconjugation applications, such as protein labeling and drug delivery, supporting studies in chemical biology and therapeutics.
Product Information
Catalog NumA92456
FormulaC27H42N4O6S
Molecular Weight550.71
CAS Number1393600-24-2
SMILESO=C(N1)N[C@](CS2)([H])[C@@]1([H])[C@@H]2CCCCC(NCCOCCOCCNC(OC[C@@H]3[C@@]4([H])[C@]3([H])CCC#CCC4)=O)=O
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