Catalog No.
Product Name
Application
Product Information
Citations
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Nucleotide Derivative
DMT-OMe-rC(Ac) (N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine) is a nucleotide derivative designed for oligoribonucleotide synthesis. This compound features protective groups that enable efficient polymerization while maintaining compatibility with various synthetic protocols. DMT-OMe-rC(Ac) is essential for researchers exploring RNA biology and developing RNA-based therapeutics. -
Purine Nucleoside Analog
5-Methoxycarbonylmethyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological efficacy is attributed to mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable in cancer research for its potential therapeutic applications and in studies focused on nucleoside metabolism and treatment resistance. -
Guanosine Analog
2′-O-2-Propyn-1-ylguanosine is a guanosine analogue with notable immunostimulatory properties. It has been shown to induce type I interferons in various animal models, thereby exhibiting antiviral effects. The functional activity of this compound is linked to the activation of Toll-like receptor 7 (TLR7). Additionally, 2′-O-2-Propyn-1-ylguanosine serves as a click chemistry reagent, featuring an alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. -
Purine Nucleoside Analog
4′-Thiouridine is a purine nucleoside analog that functions as a thio derivative of thymidine. It exhibits significant antiviral and anticancer properties, making it useful for the synthesis of 4'-thionucleosides. Additionally, 4′-Thiouridine is applicable in RNA-sequencing studies, facilitating the exploration of RNA molecular biology. -
Nucleoside Analog
5-F-UTP (5-Fluorouridine-5'-triphosphate) is a nucleoside analog that functions as a substrate for RNA polymerases during nucleic acid synthesis. This compound is utilized in research applications involving RNA synthesis, allowing for the incorporation of fluorine into RNA molecules, which can aid in the study of RNA structure and function. Its unique properties make it valuable for developing RNA-based therapeutics and molecular probes. -
Adenosine Analog
8-Chloro-2'-deoxyadenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant biological activity as a potential vasodilator and has demonstrated inhibitory effects on cancer progression. It is useful in various research applications, particularly in studying the pharmacological effects of adenosine and its derivatives in cardiovascular and oncology research. -
Purine Nucleoside Analog
5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool in cancer research. This compound can be utilized for studying the effects of nucleoside metabolism and the development of targeted therapies in oncology. -
Purine Nucleoside Analog
3′-Chloro-3′-deoxythymidine is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis in targeted cancer cells. This compound is primarily utilized in cancer research to explore therapeutic strategies for lymphoid malignancies and to further understand nucleoside analog mechanisms of action. -
Adenosine Analog
2-Methoxy-2'-deoxyadenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits vasodilatory effects on smooth muscle and has demonstrated potential in inhibiting cancer progression, making it relevant for various research applications, including cardiovascular studies and oncology. Its structural similarity to adenosine allows for exploration in drug development targeting related pathways. -
Anticancer nucleosides
4'-Ethynyl-2'-deoxycytidine is an anticancer nucleoside that selectively targets DNA replication pathways. This compound exhibits significant efficacy against various malignancies, including acute lymphoblastic leukemia and diffuse large B-cell lymphoma. It provides a valuable tool for research focused on cancer cell kinetics and therapeutic resistance. -
Nucleoside Metabolite
6-Acetamido-2-oxohexanoate primarily interacts as a nucleoside metabolite within biological systems. It serves as an important intermediate in metabolic pathways associated with nucleotide synthesis and breakdown. Research applications include studies on nucleoside metabolism, enzymatic activity, and potential therapeutic targets related to nucleic acid metabolism. -
Purine Nucleoside Analog
N4-Benzoyl-2'-deoxy-5-iodocytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This compound is valuable for research focused on understanding cancer biology and developing therapeutic strategies for hematological malignancies. -
Purine Nucleoside Analog
3'-β-Amino-2',3'-dideoxy-5'-O-methoxy trityluridine is a purine nucleoside analog that effectively inhibits DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its pharmacological mechanisms include the induction of apoptosis and disruption of cellular proliferation, making it valuable for research in cancer biology and therapeutic development. -
Purine Nucleoside Analog
2’,3’-Bis(O-t-butyldimethylsilyl)-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research focused on understanding the therapeutic potential of purine nucleoside analogs in oncology. -
Purine Nucleoside Analog
2'-O-(2-Azidoethyl)adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms are primarily driven by the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent due to its azide functionality, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing alkyne, DBCO, or BCN groups. It is a valuable tool for bioconjugation applications in chemical biology and medicinal chemistry. -
Purine Nucleoside Analog
4′,5′-Didehydro-5′-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in the study of indolent lymphoid malignancies. This compound is suitable for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
4-Amino-5-iodo-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine functions as a purine nucleoside analog, exhibiting significant antitumor activity against indolent lymphoid malignancies. This compound operates through various mechanisms, including the inhibition of DNA synthesis and the induction of apoptosis. It serves as a valuable tool in cancer research, facilitating the exploration of therapeutic strategies against lymphoid tumors. -
Adenosine Analog
N-(2-Phenoxyacetyl)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. It serves as a valuable tool in cancer research and studies related to vascular biology. -
Purine Nucleoside Analog
3'-Azido-3'-deoxy-5-fluoro-beta-L-uridine is a purine nucleoside analog that demonstrates significant antitumor activity, primarily against indolent lymphoid malignancies. Its mechanisms of action involve inhibition of DNA synthesis and induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, including those with DBCO or BCN groups. These properties make it a valuable tool for various biochemical research applications. -
Purine Nucleoside Analog
4’-Methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic applications. This compound is essential for studying the effects of nucleoside analogs in various oncological contexts. -
Purine Nucleoside Analog
Methyl 2,3,5-tri-O-benzyl-D-ribofuranoside is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. The compound functions primarily by inhibiting DNA synthesis and inducing apoptosis in target cells, making it a valuable tool for cancer research. Its unique mechanism of action facilitates investigations into therapeutic strategies for malignancies associated with purine metabolism. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-Purine is a purine nucleoside analog known for its antitumor activity. This compound primarily targets indolent lymphoid malignancies by inhibiting DNA synthesis and inducing apoptosis, thereby contributing to its potential therapeutic effectiveness in cancer research. Its applications extend to studying mechanisms of tumor cell proliferation and apoptosis in various models. -
Purine Nucleoside Analog
2'-Deoxy-2'-fluoro-alpha-D-arabinoguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This compound serves as a valuable tool in cancer research, contributing to studies aimed at understanding the effects of purine synthesis inhibition and the development of novel therapeutic strategies. -
Oligonucleotide
m7GpppUpG is an oligonucleotide that serves as an M7GpppNpG trinucleotide cap analogue. This compound facilitates the synthesis of RNA molecules with either cap 0 or cap 1 structures, making it a valuable tool for studies in RNA biology and a useful reagent in RNA manufacturing applications. Its role in modulating RNA stability and translation further supports its utility in nucleic acid research. -
Purine Nucleoside Analog
3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog that exhibits significant antitumor activity, specifically targeting indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent in cancer research. This compound is useful for studying tumor biology and evaluating potential therapeutic strategies. -
Purine Nucleoside Analog
1,4-Anhydro-2,3-di-O-isopropylidene-4-thio-D-ribitol is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, which leads to the induction of apoptosis in cancer cells. This compound serves as a valuable tool in cancer research, facilitating the study of nucleoside analogs in therapeutic applications. -
Purine Nucleoside Analog
3’-Deoxy-3’-fluoro-xylocytidine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it relevant for research on indolent lymphoid malignancies. Its application extends to studying cancer cell proliferation and exploring therapeutic pathways in oncological research. -
Purine Nucleoside Analog
2’,5’-Dideoxyuridine is a purine nucleoside analog that functions primarily by inhibiting DNA synthesis. This compound exhibits significant antitumor activity, particularly in the context of indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis and disruption of nucleotide metabolism, making it a valuable tool for research focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
2'-β-C-Methyl inosine is a purine nucleoside analog that selectively targets and inhibits critical pathways in cellular proliferation. This compound exhibits significant antitumor activity, particularly in treating indolent lymphoid malignancies, by interfering with DNA synthesis and promoting apoptosis. Its application in cancer research underscores its potential as a therapeutic agent in oncology studies. -
Purine Nucleoside Analog
5-β-D-Ribofuranosyl-2(1H)-pyridinone is a purine nucleoside analog that demonstrates prominent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer therapeutics and the development of innovative treatments targeting purine metabolism. -
MMP-2 Inhibitor
Homouridine is an uridine analogue that acts as an MMP-2 inhibitor, exhibiting an IC50 of 150 μM for compound I. This compound demonstrates significant biological activity through its ability to inhibit TNF-α binding to the TNF-αR1, making it valuable for research applications focused on inflammatory responses and extracellular matrix remodeling. Homouridine serves as a vital intermediate in the synthesis of MMP-2 inhibitors, facilitating studies in cancer and tissue repair mechanisms. -
Purine Nucleoside Analog
N6-Benzoyl-3’-O-(2-methoxyethyl)adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound can be utilized to study various aspects of cancer biology and therapeutic strategies targeting purine metabolism. -
Purine Nucleoside Analog
5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog that exerts its biological effects primarily through the inhibition of DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis and disruption of nucleic acid metabolism, making it a valuable reagent for cancer research and drug development. -
Purine Nucleoside Analog
2',3'-Di-O-acetyl-8-benzyloxy-3'-deoxy guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer effects primarily involve the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a useful tool in research applications focused on understanding and developing treatments for various types of cancer. -
Purine Nucleoside Analog
3’-O-MOE-U-2’-phosphoramidite is a purine nucleoside analog that targets cellular pathways involved in nucleic acid metabolism. Its primary biological activity includes the inhibition of DNA synthesis and the induction of apoptosis, making it relevant for research in cancer biology. This reagent is widely utilized in studies focused on antitumor mechanisms, particularly in the context of indolent lymphoid malignancies. -
Nucleoside Metabolite
15H-11,12-EETA is a nucleoside metabolite known for its role in cellular metabolism. This compound has been implicated in various biological processes, including cellular signaling and nucleic acid synthesis. Its application in research facilitates the study of nucleoside metabolism and the exploration of related metabolic pathways in both health and disease contexts. -
Purine Nucleoside Analog
2'-Chloro-N6-(4-methoxy)benzyl adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research. This compound is useful for studying the cellular responses to nucleoside analogs and their potential therapeutic effects in oncology. -
Purine Nucleoside Analog
2-Amino-8-aza-7-deaza-7-iodoguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for investigations into therapeutic strategies for lymphoid cancers and exploring the biochemical pathways involved in tumor cell proliferation. -
Nucleoside Metabolite
3-(Methylseleninyl)-L-alanine is a nucleoside metabolite that serves as a selenium-containing analogue of L-alanine. It plays a role in cellular metabolism, particularly in the synthesis of selenoproteins and antioxidant activity. This reagent is valuable for research involving metabolic pathways, selenium biochemistry, and the study of selenoamino acid derivatives in various biological systems. -
Purine Nucleoside Analog
3-Deoxy-1,2:5,6-bis-O-(1-methylethylidene)-α-D-ribo-hexofuranose is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research applications focused on therapeutic development and understanding the underlying mechanisms of tumor progression. This compound serves as an important tool for scientists investigating nucleoside analogs in oncology. -
Purine Nucleoside Analog
2'-Deoxy-8-methylamino-adenosine is a purine nucleoside analog known for its antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications aimed at understanding the therapeutic potential of nucleoside analogs in cancer treatment. -
Purine Nucleoside Analog
2-Amino-N6,N6-dimethyl-2’-deoxy-2’-fluoro-beta-D-arabino-adenosine is a purine nucleoside analog that exhibits significant antitumor activity primarily against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is a valuable tool for research into cancer biology and therapeutic development in oncology. -
Purine Nucleoside Analog
3’-Deoxy-3’,5-difluorocytidine is a purine nucleoside analog that exerts its primary effect by interfering with DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as apoptosis induction and cell cycle disruption. Its unique properties make it a valuable tool for cancer research, particularly in studies focused on DNA replication and cellular responses to genotoxic stress. -
Purine Nucleoside Analog
5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is suitable for research applications aimed at exploring therapeutic strategies in cancer treatment and understanding the molecular pathways involved in tumorigenesis. -
Purine Nucleoside Analog
2'-Deoxy-3',2-anhydrouridine is a purine nucleoside analog recognized for its potent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool in cancer research. This compound is instrumental for studies focused on the development of novel therapeutic strategies in oncology. -
Purine Nucleoside Analog
TLR7 agonist 11 is a purine nucleoside analog that engages Toll-like receptor 7 (TLR7). This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic studies. -
Purine Nucleoside Analog
N4-Benzoyl-2'-deoxy-5'-O-DMT-2',2'-difluorocytidine is a purine nucleoside analog that effectively inhibits DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis in cancer cells. It serves as a valuable tool for research into mechanisms of cancer therapy and nucleoside metabolism. -
Uridine Analog
5’-O-(4,4’-Dimethoxytrityl)-3’-O-methyluridine is an analog of uridine that targets nucleotide metabolism. It exhibits potential antiepileptic properties, making it a valuable tool for studying anticonvulsant and anxiolytic effects. This compound may also facilitate the development of novel antihypertensive agents, enhancing research in therapeutic applications related to epilepsy and hypertension. -
Nucleotide Analog
3′-Phenylcarbamate-UTP is a nucleotide analog derived from uridine triphosphate (UTP) through phenylcarbamate modification. This compound can serve as a substrate for RNA polymerases, facilitating studies in RNA synthesis and turnover. Its unique structural modifications make it a valuable tool in exploring nucleotide interactions and the effects of chemical modifications on nucleic acid biochemistry. Researchers may utilize 3′-Phenylcarbamate-UTP in various applications, including the development of RNA-based therapeutics and the investigation of ribonucleotide metabolism. -
Purine Nucleoside Analog
2'-O-Methyl-N2,N2-dimethyl-guanosine is a purine nucleoside analog that primarily targets nucleic acid synthesis. It exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it valuable for research in cancer therapeutics and relevant biochemical studies.
