SIRT2-IN-15 is a selective inhibitor of the SIRT2 deacetylase and deamyloacylase enzymes, demonstrating IC50 values of 7 μM and 37 μM, respectively. This compound modulates cellular acetylation states, making it a valuable tool for investigating the roles of SIRT2 in various biological processes, including neurodegenerative diseases, cancer metabolism, and aging. SIRT2-IN-15 can be utilized in research applications focusing on the molecular mechanisms of SIRT2-related pathways and potential therapeutic targets.
SIRT2-IN-15 is a selective inhibitor of the SIRT2 deacetylase and deamyloacylase enzymes, demonstrating IC50 values of 7 μM and 37 μM, respectively. This compound modulates cellular acetylation states, making it a valuable tool for investigating the roles of SIRT2 in various biological processes, including neurodegenerative diseases, cancer metabolism, and aging. SIRT2-IN-15 can be utilized in research applications focusing on the molecular mechanisms of SIRT2-related pathways and potential therapeutic targets.
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