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Z-VEID-AFC

Catalog No.: A25327
Fluorescent Substrate
Z-VEID-AFC is a fluorescent substrate specifically designed for the detection of caspase-6 activity. Upon cleavage by active caspase-6, it releases a fluorescent signal, making it useful for monitoring apoptotic processes in various biological systems. This reagent serves as a valuable tool in studies related to cell death, neurodegeneration, and tumor biology, facilitating the investigation of caspase-related pathways in research applications.
Z-VEID-AFC 219138-06-4 Fluorescent Substrate
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionZ-VEID-AFC is a fluorescent substrate specifically designed for the detection of caspase-6 activity. Upon cleavage by active caspase-6, it releases a fluorescent signal, making it useful for monitoring apoptotic processes in various biological systems. This reagent serves as a valuable tool in studies related to cell death, neurodegeneration, and tumor biology, facilitating the investigation of caspase-related pathways in research applications.
Product Information
Catalog NumA25327
FormulaC38H44F3N5O12
Molecular Weight819.78
CAS Number219138-06-4
Sequence{Z}-Val-Glu-Ile-Asp-{AFC}
Sequence shortening{Z}-VEID-{AFC}
SMILESC(F)(F)(F)C=1C=2C(=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(OCC3=CC=CC=C3)=O)[C@@H](C)C)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CC(O)=O)=O)=CC2)OC(=O)C1
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