KMG-301AM TFA is an acetoxymethyl ester derivative of KMG-301, designed as a fluorescent probe targeting Mg2+ within mitochondria. Once inside the mitochondria, it is hydrolyzed to KMG-301, which selectively measures Mg2+ concentrations in live cells, as it remains confined within the mitochondria due to the impermeability of the mitochondrial membrane. This probe is suitable for assessing Mg2+ transport and monitoring changes in mitochondrial Mg2+ levels, providing valuable insights in cellular models of mitochondrial function and dysfunction.
KMG-301AM TFA is an acetoxymethyl ester derivative of KMG-301, designed as a fluorescent probe targeting Mg2+ within mitochondria. Once inside the mitochondria, it is hydrolyzed to KMG-301, which selectively measures Mg2+ concentrations in live cells, as it remains confined within the mitochondria due to the impermeability of the mitochondrial membrane. This probe is suitable for assessing Mg2+ transport and monitoring changes in mitochondrial Mg2+ levels, providing valuable insights in cellular models of mitochondrial function and dysfunction.
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