H-FluNox is a selective fluorescent probe designed to detect labile heme through biomimetic N-oxide deoxygenation, which activates its fluorescence. This compound demonstrates over 100-fold selectivity for labile heme compared to Fe(II), facilitating the differentiation of labile heme from intracellular Fe(II) pools. H-FluNox's high sensitivity enables the detection of labile heme at the subcellular level, making it an invaluable tool for studies of heme dynamics and related biological processes.
H-FluNox is a selective fluorescent probe designed to detect labile heme through biomimetic N-oxide deoxygenation, which activates its fluorescence. This compound demonstrates over 100-fold selectivity for labile heme compared to Fe(II), facilitating the differentiation of labile heme from intracellular Fe(II) pools. H-FluNox's high sensitivity enables the detection of labile heme at the subcellular level, making it an invaluable tool for studies of heme dynamics and related biological processes.
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