YO-PRO-1 is a green fluorescent dye designed for detecting apoptotic and necrotic cells through its inability to penetrate intact cell membranes. It exhibits a strong affinity for DNA; when bound, it emits a bright green fluorescence (Ex/Em: 488/530±30 nM), facilitating the identification of cellular states. YO-PRO-1 is commonly utilized in conjunction with other reagents, such as Propidium Iodide, enhancing the analysis of cell viability and apoptosis in various biological research applications.
YO-PRO-1 is a green fluorescent dye designed for detecting apoptotic and necrotic cells through its inability to penetrate intact cell membranes. It exhibits a strong affinity for DNA; when bound, it emits a bright green fluorescence (Ex/Em: 488/530±30 nM), facilitating the identification of cellular states. YO-PRO-1 is commonly utilized in conjunction with other reagents, such as Propidium Iodide, enhancing the analysis of cell viability and apoptosis in various biological research applications.
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