Factor Xa

Catalog No.Inhibitor Name Factor XaOther
A10800Rivaroxaban
**
Prothrombinase
A10082Apixaban
****
A14317Edoxaban
***
Thrombin,FIXa

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. Apixaban (BMS-562247-01)

    Catalog No. A10082
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    Factor Xa inhibitor
    Apixaban is an anticoagulant for the prevention of venous thromboembolism and venous thromboembolic events. Learn More
  2. 5-R-Rivaroxaban

    Catalog No. A14979
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    Factor Xa inhibitor
    5-R-Rivaroxaban is (R) enantiomer of Rivaroxaban. Rivaroxaban is a novel, oral, direct Factor Xa (FXa) inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders. Learn More
  3. Edoxaban (tosylate Monohydrate)

    Catalog No. A14317
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    Factor Xa inhibitor
    Edoxaban is a selective factor Xa inhibitor with Ki of 0.561 nM Learn More
  4. DPC-423

    Catalog No. A14099
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    factor Xa inhibitor
    DPC423 is a highly potent and orally bioavailable pyrazole antithrombotic agent. Learn More
  5. ABT333

    Catalog No. A13878
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    NS5B Inhibitor
    ABT333 is an NS5B non-nucleoside polymerase inhibitor. Learn More
  6. Betrixaban

    Catalog No. A12518
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    FXa Inhibitor
    Betrixaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is potent, orally active and highly selective for factor Xa, being selected from a group of similar compounds for its low hERG affinity. Learn More
  7. Rivaroxaban Diol

    Catalog No. A12411
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    Rivaroxaban is an oxazolidinone derivative optimized for inhibiting both free Factor Xa and Factor Xa bound in the prothrombinase complex. Learn More
  8. Letaxaban (TAK-442)

    Catalog No. A12871
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    factor Xa inhibitor
    Letaxaban, also known as TAK-442, is a potent, selective, and orally active factor Xa inhibitor, which is a tetrahydropyrimidin-2(1H)-one derivative. TAK-442 inhibited endogenous FXa activity in platelet-poor human [half-maximal inhibitory concentration (IC(50)): 53 nM, TAK-442] and rat (IC(50): 32 nM, TAK-442) plasma. Learn More
  9. Razaxaban

    Catalog No. A12870
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    factor Xa inhibitor
    Razaxaban is a selective, potent, and orally bioavailable inhibitor of coagulation factor Xa. Learn More
  10. Otamixaban (FXV 673)

    Catalog No. A11517
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    factor Xa inhibitor
    Otamixaban(FXV 673) is an intravenous direct factor Xa inhibitor. Learn More
  11. Rivaroxaban (Xarelto)

    Catalog No. A10800
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    Factor Xa inhibitor
    Rivaroxaban is an oxazolidinone derivative optimized for inhibiting both free Factor Xa and Factor Xa bound in the prothrombinase complex. Learn More
  12. BMS-740808

    Catalog No. A10158
    Factor Xa inhibitor

    BMS-740808 is a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa.

    Learn More
  13. Edoxaban tosylate

    Catalog No. A15076
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    Factor Xa inhibitor
    Edoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention. Learn More

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