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$0.00 Factor Xa
| Catalog No. | Inhibitor Name | Factor Xa | Other |
|---|---|---|---|
| A10800 | Rivaroxaban | ** | Prothrombinase |
| A10082 | Apixaban | **** | |
| A14317 | Edoxaban | *** | Thrombin,FIXa |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
17 Item(s)
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BMS-654457
Catalog No. A21704 Factor XIa (FXIa) inhibitorBMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa), binding with human and rabbit FXIa with Kis of 0.2 and 0.42 nM, respectively. Learn More -
Edoxaban
Catalog No. A18015 factor Xa (FXa) inhibitorEdoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention. Learn More -
RWJ-445167
Catalog No. A12154 dual inhibitor of thrombin and factor XaRWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity. Learn More -
Fondaparinux Sodium
Catalog No. A17918 factor Xa inhibitorFondaparinux sodium is a factor Xa inhibitor to form the high affinity binding site for the anti-coagulant factor antithrombin III (ATIII). Learn More -
ABT333
Catalog No. A13878 NS5B InhibitorABT333 is an NS5B non-nucleoside polymerase inhibitor. Learn More -
Edoxaban tosylate
Catalog No. A15076 Factor Xa inhibitorEdoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention. Learn More -
5-R-Rivaroxaban
Catalog No. A14979 Factor Xa inhibitor5-R-Rivaroxaban is (R) enantiomer of Rivaroxaban. Rivaroxaban is a novel, oral, direct Factor Xa (FXa) inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders. Learn More -
Edoxaban (tosylate Monohydrate)
Catalog No. A14317 Factor Xa inhibitorEdoxaban is a selective factor Xa inhibitor with Ki of 0.561 nM Learn More -
DPC-423
Catalog No. A14099 factor Xa inhibitorDPC423 is a highly potent and orally bioavailable pyrazole antithrombotic agent. Learn More -
Apixaban (BMS-562247-01)
Catalog No. A10082 Factor Xa inhibitorApixaban is an anticoagulant for the prevention of venous thromboembolism and venous thromboembolic events. Learn More -
Betrixaban
Catalog No. A12518 FXa InhibitorBetrixaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is potent, orally active and highly selective for factor Xa, being selected from a group of similar compounds for its low hERG affinity. Learn More -
Rivaroxaban Diol
Catalog No. A12411 Rivaroxaban is an oxazolidinone derivative optimized for inhibiting both free Factor Xa and Factor Xa bound in the prothrombinase complex. Learn More -
Letaxaban (TAK-442)
Catalog No. A12871 factor Xa inhibitorLetaxaban, also known as TAK-442, is a potent, selective, and orally active factor Xa inhibitor, which is a tetrahydropyrimidin-2(1H)-one derivative. TAK-442 inhibited endogenous FXa activity in platelet-poor human [half-maximal inhibitory concentration (IC(50)): 53 nM, TAK-442] and rat (IC(50): 32 nM, TAK-442) plasma. Learn More -
Razaxaban
Catalog No. A12870 factor Xa inhibitorRazaxaban is a selective, potent, and orally bioavailable inhibitor of coagulation factor Xa. Learn More -
Otamixaban (FXV 673)
Catalog No. A11517 factor Xa inhibitorOtamixaban(FXV 673) is an intravenous direct factor Xa inhibitor. Learn More -
Rivaroxaban (Xarelto)
Catalog No. A10800 Factor Xa inhibitorRivaroxaban is an oxazolidinone derivative optimized for inhibiting both free Factor Xa and Factor Xa bound in the prothrombinase complex. Learn More -
BMS-740808
Catalog No. A10158 Factor Xa inhibitorBMS-740808 is a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa.
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