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Biological Activity
RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.91 mL | 114.55 mL | 229.1 mL |
| 0.5 mM | 4.58 mL | 22.91 mL | 45.82 mL |
| 1 mM | 2.29 mL | 11.46 mL | 22.91 mL |
| 5 mM | 0.46 mL | 2.29 mL | 4.58 mL |
*The above data is based on the productmolecular weight 436.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12154 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 226566-43-4 |
| Formula | C18H24N6O5S |
| M. Wt | 436.49 |
| Purity | >98% |
| Synonyms | 3DP-10017, 3DP10017, RWJ445167, RWJ 445167 |
| SMILES | O=C(NCCONC(N)=N)CN1C(C)=CC=C(NS(=O)(C2=CC=CC(C)=C2)=O)C1=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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