Catalog No.
Product Name
Application
Product Information
Citations
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Lead Compound
3-Amino-1,2,4-triazin-5(2H)-one is a lead compound targeting various biological pathways. This organic triazine derivative exhibits a wide array of biological activities, including antibacterial, antifungal, antiviral, and potential antitumor effects, which are influenced by its chemical structure and functional groups. It serves as a valuable reagent for research applications in pharmacology and medicinal chemistry, facilitating the discovery of new therapeutic agents. -
Antibiotic
Albiducin A is an antibiotic derived from the fungus Hymenoscyphus albidus, known for its antibacterial and anticancer properties. It demonstrates a minimum inhibitory concentration (MIC) range against bacteria and fungi of 16.7-66.7 mg/mL. In cellular assays, Albiducin A exhibits IC50 values of 6.1 μg/mL for mouse fibroblast L929 cells and 2.7 μg/mL for human cervical carcinoma KB3-1 cells. This compound is of significant interest for research in infection and cancer treatment. -
Fungicide
Iprovalicarb is a fungicide that functions by inhibiting fungal growth, targeting specific pathways involved in fungal cell metabolism. This compound is primarily utilized in research focused on fungal diseases, particularly within the winemaking industry. Its effectiveness against various fungal pathogens makes it a valuable tool for studying disease management strategies and developing protective measures in viticulture. -
Antifungal Agent
D13 is an acylhydrazone derivative that exhibits potent antifungal activity. It has demonstrated effectiveness against murine sporotrichosis, making it a valuable candidate for research in fungal infections. Its unique mechanism of action and efficacy profile support its potential applications in the study and treatment of antifungal resistance and related diseases. -
Anti-Fungal Agent
Haliangicin B is an anti-fungal agent primarily targeting filamentous fungi and demonstrating efficacy against oomycetes. This compound exhibits potent biological activity, making it useful for research applications focused on fungal pathogenesis and the development of antifungal therapies. Its selective action excludes antibacterial properties, positioning it specifically within the realm of mycology research. -
Antimicrobial Agent
Terrestribisamide, also known as (E)-N,N′-Diferuloylputrescine, serves as an antimicrobial agent derived from the dried fruits of Tribulus terrestris. This compound exhibits notable antibacterial, antifungal, antioxidant, and anticancer activities, making it a valuable tool for various biological research applications. Its diverse pharmacological properties contribute to its potential in studying microbial resistance and cancer therapies. -
Isomer of Pneumocandin B0
Pneumocandin C0 is an isomer of Pneumocandin B0 known for its antifungal properties. It exhibits significant activity against fungal infections, making it suitable for research in the development of antifungal agents. Derived from the fermentation of Glarea lozoyensis under conditions of high residual fructose concentration, Pneumocandin C0 serves as a valuable compound for studies focusing on fungal pathogenesis and treatment strategies. -
Fungal Inhibitor
BHBM is an aromatic acylhydrazone compound that acts as a potent antifungal agent targeting Cryptococcus neoformans. Its high bactericidal activity makes it a valuable tool for research applications focused on fungal infections and the development of new antifungal therapies. BHBM can be used to explore mechanisms of action and resistance in fungi, contributing to advancements in infectious disease research. -
Antifungal Agent
YZK-C22 is an antifungal agent characterized by its unique 1,2,3-thiadiazol-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole framework. It exhibits broad-spectrum fungicidal activity, making it a promising candidate for developing effective antifungal treatments. This compound is suitable for research applications focused on fungal pathogen control and antifungal drug discovery. -
Anti-Fungal Agent
Neocopiamycin B is an antifungal agent derived from the strain Streptomyces hygroscopicus var. crystallogenes. It exhibits potent antifungal activity against various fungal pathogens, making it a valuable tool for studying fungal infections and developing new antifungal therapies. This compound is applicable in research focused on mycology and the exploration of novel antifungal mechanisms. -
Group II introns Inhibitor
Group II intron-IN-1 acts as an inhibitor of fungal Group II introns, demonstrating an IC50 of 3 μM. This compound is valuable for research focusing on fungal infections, particularly those caused by Candida species. Its ability to selectively target intronic processes makes it a significant tool for studying fungal biology and the mechanisms of infection. -
Anti-tubercular Agent
Giparmen is an anti-tubercular agent that demonstrates significant efficacy in targeting Mycobacterium tuberculosis. This compound shows promise for further research into fungal infections, specifically those caused by Candida species. Its unique mechanism and biological activity make it a valuable tool for investigators studying tuberculosis and fungal pathogenesis. -
Antibiotic
Epoformin is a fungal cyclohexene epoxide derived from Diplodia quercivora, primarily acting as an antibiotic. It exhibits inhibitory effects on rye seedling sheath growth and demonstrates notable antifungal activity, particularly against pathogens such as Phytophthora cinnamomi and Phytophthora plurivora. Epoformin is suitable for research applications focusing on antimicrobial mechanisms and the study of plant-pathogen interactions. -
Antifungal
Neocryptolepine-Cl is a selective inhibitor of Bcthi4, demonstrating potent antifungal activity against Botrytis cinerea, with an EC50 value of 0.56 μg/mL. This compound is useful for research applications targeting fungal pathogens, particularly in studies investigating antifungal mechanisms and resistance. Neocryptolepine-Cl may facilitate the development of new antifungal strategies and therapies. -
Phytoalexin
Moracin B is a phytoalexin targeting fungal pathogens. This compound exhibits significant antifungal activity and can be isolated from infected mulberry (Morus alba Linne) tissues, specifically the cortex and phloem, associated with Fusarium solani f. sp. mori. Moracin B serves as a valuable tool for investigating plant disease resistance mechanisms and demonstrates potential applications in the control of plant diseases caused by microbial infections. -
Antibiotic
Destomycin B is an antibiotic with a primary mechanism of action against fungal pathogens. This compound exhibits significant antifungal activity and also possesses anthelmintic properties, making it valuable for research focused on parasitic infections. Its unique biological activities render it an essential reagent for studies involving fungal resistance and helminthic diseases. -
Antifungal Compound
Lanomycin is an antifungal compound that targets various fungal pathogens, including Candida species and dermatophytes. It exhibits potent antifungal activity, making it suitable for research applications focused on fungal infections and therapeutic development. Lanomycin's mechanism of action can help elucidate the biology of fungal resistance and guide the discovery of novel antifungal agents. -
Antifungal Agent
8-Acetylverrucarin L is a mycotoxin with potent antifungal properties. It demonstrates significant cytotoxicity against cancer cell lines HCT116 and A2780S, exhibiting an IC100 value of 9.77 ng/mL. In addition to its antitumor effects, 8-Acetylverrucarin L shows effective antifungal activity against Saccharomyces cerevisiae, Candida albicans, and Geotrichum candidum, making it a valuable reagent for research in both cancer biology and fungal infections. -
Antibiotic
Aranochlor A is an antibiotic derived from the marine organism Pseudoarachniotus roseus. This compound demonstrates significant antibacterial and antifungal activities, making it a valuable reagent for research in microbiology and pharmacology. Its unique properties may contribute to studies focused on developing new antimicrobial agents and understanding resistance mechanisms in pathogens. -
Anti-Fungal Agent
Phoslactomycin F is an anti-fungal agent that targets fungal organisms with high efficacy. It demonstrates weak activity against Gram-positive bacteria, highlighting its specific application in fungal research. This compound can be utilized in studies exploring fungal pathogenesis and the development of novel antifungal therapies. -
Antibiotic
Arginomycin is a nucleoside antibiotic that primarily targets the growth mechanisms of Gram-positive bacteria and fungi. This compound exhibits potent antibacterial and antifungal activity, making it useful in microbiological research and the study of microbial resistance. Its ability to inhibit the proliferation of specific pathogens supports investigations into antimicrobial therapies and the development of new antibiotics. -
Anticancer And Antimicrobial Agent
α-Thujaplicin is a potent antimicrobial agent that exhibits anticancer activity by targeting Carboxypeptidase A, with an IC50 of 32.4 μM. This compound demonstrates significant antifungal activity against various plant-pathogenic fungi, with MICs ranging from 12.0 to 50.0 μg/mL. Additionally, α-Thujaplicin shows antibacterial properties against Legionella pneumophila and Enterococcus faecalis, with respective MICs of 12.5-50 μg/mL and 1.56 μg/mL. Moreover, it inhibits the germination of Echinochloa utilis seeds and has been associated with the suppression of lymphocytic leukemia and stomach cancer. -
Antibiotic
Pyrrolomycin B is a pyrrole antibiotic that exhibits potent antibacterial activity against both Gram-positive and Gram-negative bacteria, as well as antifungal properties. This compound is employed in various research applications aimed at understanding bacterial resistance mechanisms and evaluating its potential therapeutic effects against infectious diseases. Its broad-spectrum efficacy makes it a valuable tool for microbiological studies and antibiotic development. -
Broad-spectrum antifungal Agent
Pramiconazole is a broad-spectrum antifungal agent that targets 14α-demethylase, disrupting ergosterol synthesis in fungal cell membranes. It exhibits oral bioactivity and is effective against a variety of fungal infections, including those affecting the skin, hair, nails, oral cavity, and genital mucosa. This compound is valuable in research focused on antifungal therapies and the mechanisms of antifungal resistance. -
Antifungal Agent
Antifungal Agent 150 is an antifungal compound primarily targeting ergosterol biosynthesis, effectively inhibiting key enzymes involved in this pathway. It demonstrates significant activity against phytopathogenic fungi, providing lesion suppression in planta. This agent is suitable for researching plant diseases caused by Rhizoctonia solani, including banded leaf and sheath blight in maize. -
Antibiotic
Glucoallosamidin A is a glycoside antibiotic that targets chitinase activity, effectively inhibiting the enzyme's function. It demonstrates significant biological activity against Candida albicans ATCC 10231, achieving an IC50 of 3.4 μg/mL. This compound is valuable for research into antifungal therapies and elucidating the role of chitinase in pathogen resistance. -
Antifungal Metabolite
Dihydrocompactin is an antifungal metabolite that acts primarily as an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase (HMG-CoA reductase). This compound, derived from Penicillium citrinum, exhibits significant antifungal activity and is valuable in studying fungal infections and metabolic pathways. Dihydrocompactin may be used in research focused on the development of antifungal agents and the elucidation of HMG-CoA reductase's role in cellular processes. -
Antifungal Agent
Anticapsin is a potent inhibitor of glucosamine-6-phosphate synthase, functioning primarily as an antifungal agent. It exhibits efficacy against various fungal pathogens by disrupting cell wall synthesis, leading to compromised integrity and cellular death. This compound is valuable in antifungal research applications, especially in studying mechanisms of resistance and evaluating new therapeutic strategies. -
Antifungal Agent
MFB-1041 is an orally active antifungal agent that targets fungal cell function. Though it has poor oral absorption, MFB-1041 is known to facilitate the binding of the drug to serum albumin, which may enhance its efficacy. This compound is utilized in research focused on antifungal mechanisms and therapeutic development. -
Antimicrobial Agent
Concanamycin F is a specific inhibitor of V-type ATPase, exhibiting a Ki value of 0.02 nM. This compound demonstrates a range of biological activities, including antifungal, antiviral, immunosuppressive, and cytotoxic effects. It serves as a valuable tool in biochemical research, enabling investigations into cellular processes and the study of ATPase function. -
Laccase Inhibitor
Laccase-IN-6 is a potent laccase inhibitor with an IC50 of 0.097 nM. This compound demonstrates a broad-spectrum anti-fungal activity, effectively disrupting normal fungal morphology. Laccase-IN-6 is suitable for research applications focused on fungal infections and the role of laccase in pathogenicity. -
Antifungal Agent
Dihydrobiochanin A is a flavonoid with demonstrated antifungal activity. Isolated from Swartzia polyphylla, it is primarily used in research to investigate its potential as a therapeutic agent against fungal infections. Its efficacy in combating various fungal strains makes it a valuable tool in the study of antifungal mechanisms and treatments. -
Antifungal Compound
SM-4470 is an orally active antifungal compound targeting a broad spectrum of fungal pathogens. It demonstrates significant inhibitory activity against yeast, Aspergillus species, and dermatophytes in vitro. This compound is suitable for research applications focused on antifungal mechanisms and the development of novel therapeutic strategies. -
Anti-Bacterial/Fungal Agent
Aspochalasin A is an anti-bacterial and anti-fungal agent that targets microbial cell wall synthesis. It demonstrates significant inhibitory activity against a range of pathogenic bacteria and fungi, making it a valuable tool in the study of antimicrobial resistance. Research applications include examining its efficacy in infection models and investigating potential therapeutic uses in treating bacterial and fungal infections. -
Anti-Fungal Agent
Crotocin is an anti-fungal agent that primarily targets Cryptococcus neoformans, Candida albicans, and Trichophyton species. It exhibits significant biological activity against these fungi, making it valuable for research into antifungal therapies and mechanisms of action. Notably, its efficacy may be compromised in the presence of blood, indicating potential considerations for in vivo applications. -
Antitumor Antibiotic
Glidobactin G is an antitumor antibiotic that exhibits potent activity against pathogenic fungi and yeast. In preclinical studies, Glidobactin G has demonstrated the ability to extend survival in mice inoculated with leukemia P388 cells. This compound is of significant interest for research in cancer therapeutics and antifungal treatments. -
Anti-Fungal Agent
Maniwamycin A is an anti-fungal agent that selectively inhibits fungal growth by interfering with cellular processes. This compound exhibits potent antifungal activity against a range of fungal strains, making it valuable for studying fungal biology and testing antifungal therapies. Its application in research provides insights into fungal resistance mechanisms and potential therapeutic strategies. -
Antibiotic
Polyoxin H is a nucleoside antifungal antibiotic that targets fungal cell wall synthesis. It exhibits potent activity against various fungal pathogens, particularly in the treatment of rice sheath blight. This compound is valuable in agricultural research, helping to develop effective strategies for crop protection against fungal diseases. -
Antifungal Agent
(E)-4-Methyl-5-styrylbenzene-1,3-diol is an antifungal agent that demonstrates significant activity against various fungal pathogens. This compound is notable for its potential applications in the development of antifungal therapies, with a natural source being Dracaena cochinchinensis (Lour.) S. C. Chen. Researchers may employ this reagent to explore mechanisms of antifungal action and to evaluate its efficacy in vitro and in vivo systems. -
Antifungal Agent
Antifungal Agent 28 is a potent and selective antifungal compound that targets various pathogenic fungi. It demonstrates significant inhibitory effects against both C. albicans and non-albicans species, including strains resistant to fluconazole. Additionally, Antifungal Agent 28 effectively inhibits Cryptococcus and Aspergillus species, as well as disrupting mature biofilms formed by Candida species. This compound is valuable for researching antifungal resistance and developing new therapeutic strategies. -
Anticancer Agent
Cytovaricin is an anticancer agent that demonstrates the ability to inhibit the proliferation of Yoshida sarcoma cells. In addition to its primary activity, it exhibits modest antifungal effects against phytopathogenic fungi and shows activity against Chlorella. This compound is of interest for research applications focused on cancer cell growth inhibition and exploring potential antifungal properties. -
Sesquiterpenoid Compound
Eremofortin B is a sesquiterpenoid compound with demonstrated activity as a potent inhibitor of fungal growth. This compound exhibits significant biological effects, making it a valuable tool for research in mycology and potential applications in antifungal drug development. Its ability to disrupt cellular processes in fungi highlights its relevance for investigating new therapeutic agents against fungal infections. -
Anti-Fungal Agent
Gladiolic acid is an anti-fungal agent that exhibits potent activity against various fungal species, including Absidia glauca, Byssochlamys fulva, and Trichophyton mentagrophytes. Its efficacy in inhibiting fungal growth makes it a valuable reagent for studies focusing on fungal pathogenesis and the development of antifungal therapies. This compound can serve as a critical tool in research applications aimed at understanding fungal resistance mechanisms and exploring new antifungal strategies. -
Antibiotic
Polyoxin F is a nucleoside antibiotic that targets fungal pathogens, exhibiting potent antifungal activity. It is particularly effective against rice sheath blight, making it a valuable reagent for agricultural research focusing on crop protection and disease management. This compound can be utilized in studies assessing its mechanisms of action and efficacy against various fungal species. -
Depsidone
Nidulin, a depsidone derived from the marine fungus Aspergillus unguis, exhibits significant antifungal and antibacterial properties. It demonstrates inhibitory activity against pathogenic strains, including Pseudomonas aeruginosa, Methicillin-resistant Staphylococcus aureus, and Candida albicans, with inhibition zones measuring 9.5 mm, 9.0 mm, and 9.0 mm, respectively. Additionally, Nidulin demonstrates potent larvicidal effects against brine shrimp, making it a valuable compound for research in microbial resistance and pest control. -
Antibiotic
Eupenoxide is an antibiotic that primarily targets fungal pathogens. It exhibits significant antifungal activity and is produced by certain species of the genus Eupenicillium. This compound is valuable for research applications investigating antifungal mechanisms and the development of new antimicrobial agents. -
Anti-Fungal Agent
Chlorflavonin is an antifungal agent that targets a range of fungal pathogens, including Aspergillus, yeast, and Botrytis species. Notably, it exhibits potent activity against Aspergillus fumigatus, with a minimum inhibitory concentration determined at 0.08 μg/mL. This compound is utilized in research applications focused on fungal infection prevention and treatment. -
Antibiotic
α-Prumycin hydrochloride is a carbohydrate antibiotic that primarily targets fungal pathogens. It exhibits effective antifungal activity while displaying minimal antibacterial properties. This compound is utilized in research applications for studying fungal infections and understanding antibiotic mechanisms. -
Anti-Bacterial/Fungal Agent
Clavalanine is an anti-bacterial and anti-fungal agent that specifically inhibits a range of bacterial and fungal strains. Its mechanism of action involves disruption of microbial cell wall synthesis, leading to cell lysis and death. Clavalanine is utilized in research applications focused on investigating and combating infectious diseases caused by resistant microbial strains. -
Antimycotic Photosensitizer
Antifungal Agent 87 is a potent photodynamic therapy (PDT) antimycotic photosensitizer, demonstrating an IC50 of 1 nM against Trichophyton rubrum. This agent induces antifungal effects through light activation, facilitating the generation of reactive oxygen species that damage fungal cells. It holds significant potential for research in fungal infections and the development of novel therapeutic approaches utilizing photodynamic mechanisms.
