Catalog No.
Product Name
Application
Product Information
Citations
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Anti-Bacterial Agent
Polymyxin P2 is a cationic polypeptide antibiotic that targets and disrupts bacterial membranes. Primarily effective against Gram-positive bacteria, it exhibits notable antibacterial activity through its ability to interfere with cell wall integrity. This compound is widely utilized in research focused on bacterial pathogenesis and the development of novel antimicrobial agents. -
Bacterial IMPDH Inhibitor
IMPDH-IN-1 is a selective inhibitor of bacterial inosine 5'-monophosphate dehydrogenase (IMPDH), targeting the catalytic domain of the enzyme. This compound demonstrates potent inhibitory activity against IMPDH from key bacterial pathogens, including Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli. It serves as a valuable tool for research into bacterial metabolism and the development of novel antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 254 is an activator of the dispersion sensor DspS, effectively dispersing biofilms formed by Pseudomonas aeruginosa. At a concentration of 50 μM, this compound can successfully dislodge mature, 7-day-old biofilms. Additionally, Antibacterial Agent 254 enhances the antibacterial activity of Ciprofloxacin against P. aeruginosa and upregulates the expression of key matrix-degrading enzyme genes, including pelA, pslG, and eddA. These properties make it a valuable tool for research into biofilm inhibition and bacterial resistance mechanisms. -
Anti-Bacterial Agent
Nocardicyclin A is an anti-bacterial agent that exhibits potent activity against Gram-positive bacteria, mycobacteria, and Nocardia species. Its mechanism of action involves the inhibition of bacterial protein synthesis, making it a valuable compound for research into bacterial resistance and infection control. This reagent is ideal for studies focused on the effectiveness of antibacterial therapies and the development of new antimicrobial agents. -
Antibacterial Agent
GaMF1.39 is an antimycobacterial agent that targets the F-ATP synthase subunit γ. This compound demonstrates significant anti-tuberculosis activity, particularly when used in conjunction with electron transport chain inhibitors. Its ability to disrupt ATP synthesis makes it a valuable tool for research in combating mycobacterial infections. -
Antibacterial Agent
ω-azido-C6 Ceramide is an antibacterial agent that disrupts membrane potential. It demonstrates significant antibacterial activity against Neisseria species, with a minimum inhibitory concentration (MIC) of 2 µg/ml for both N. meningitidis MC58 and N. gonorrhoeae FA1090. This compound is valuable for research into membrane-targeting antibiotics and the mechanisms of bacterial resistance. -
Antibacterial Agent
Drosophilin is an antibacterial agent derived from fungi, encompassing variants such as Drosophilin A, B, C, and D. It specifically targets and inhibits the growth of Gram-positive bacteria. This compound is utilized in research to study antibacterial mechanisms and the potential development of novel therapeutic agents against bacterial infections. -
Antibacterial Agent
5-Hydroxysophoranone is a flavanone derived from Erythrina subumbrans, demonstrating potential as an antibacterial agent. This compound exhibits weak antibacterial activity against various strains of Streptococcus, providing a basis for research into its therapeutic applications in combating bacterial infections. Further studies may elucidate its mechanisms of action and efficacy in medicinal chemistry. -
Anti-Bacterial Agent
Oganomycin A is an antibiotic agent that exhibits enhanced stability compared to traditional cephalosporins. It demonstrates effectiveness against a range of Gram-positive and Gram-negative bacteria, with a notable potency against Gram-negative strains. This compound is suitable for research applications focused on bacterial resistance mechanisms and the development of new antibacterial therapies. -
Anti-bacterial Agent
ABT-255 free base is an orally active anti-bacterial agent targeting diverse bacterial strains. It demonstrates strong in vitro efficacy against both drug-susceptible and drug-resistant Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) ranging from 0.016 to 0.031 μg/mL. Additionally, ABT-255 exhibits effectiveness against Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli, and has been shown to reduce viable counts of drug-resistant Mycobacterium tuberculosis in CF-1 mouse models. This compound is valuable for research aimed at understanding and treating pulmonary tuberculosis. -
Antibacterial Agent
Cochliodone A is a bioactive compound derived from the deep-sea fungus Chaetomium sp., functioning primarily as an antibacterial agent. It demonstrates significant antibacterial activity, with minimal inhibitory concentrations (MICs) against various bacterial strains, including 15.3 μg/mL for V. vulnificus and 15.9 μg/mL for S. aureus ATCC 43300. Additionally, Cochliodone A exhibits anticancer properties, with IC50 values of 28.1 μM for A549, 20.7 μM for HeLa, and 23.2 μM for Hep G2 cancer cell lines, making it a valuable tool for pharmacological research. -
GlcN-6-P Synthase Inhibiotor
FMDP is a selective inhibitor of GlcN-6-P Synthase, demonstrating significant anti-candidal activity. Additionally, when covalently linked to polyethylene glycol in nanoparticle form, FMDP exhibits strong anticancer properties. This compound serves as a valuable tool in research applications focused on fungal infections and cancer therapeutics. -
Bacterial Inhibitor
4-Hydroxysphinganine (C17 base) is a bacterial inhibitor that plays a critical role in membrane structure for various organisms, including fungi, plants, and bacteria. It is essential for maintaining membrane integrity, regulating cellular growth, and facilitating the heat stress response in yeast. Additionally, 4-Hydroxysphinganine acts as a precursor for the synthesis of key lipid mediators, such as PHS 1-phosphate and inositol phosphorylceramide. Its properties also support keratinocyte differentiation, making it relevant for applications in dermatology and cosmetic research. -
Anti-Bacterial Agent
Griseolutein A is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. This compound demonstrates potential for use in research focused on bacterial infections and antibiotic resistance. Its efficacy makes it a valuable reagent for studies in microbiology and pharmaceutical development. -
Anti-Bacterial Agent
Nocathiacin III is an anti-bacterial agent with demonstrated effectiveness against Gram-positive bacteria. It exhibits strong activity against methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP), and multidrug-resistant Enterococcus faecalis (MREF). This compound serves as a valuable tool for research into bacterial resistance mechanisms and the development of novel antimicrobial therapies. -
Antibacterial Agent
Antibacterial agent 258 (Compound 11e) disrupts bacterial cell membranes, demonstrating potent antibacterial activity against various Gram-positive bacteria, with a minimum inhibitory concentration (MIC) of 1-2 μg/mL for Staphylococcus aureus. The compound exhibits low hemolytic activity and minimal cytotoxicity, making it a promising candidate for therapeutic applications. Additionally, antibacterial agent 258 shows effective anti-infectious efficacy in mouse models, supporting its potential for further research in infection control. -
Antibacterial Agent
Antibacterial agent 163, a hydroxyquinoline derivative, functions as a potent inhibitor of bacterial growth. This compound is particularly effective against methicillin-resistant Staphylococcus aureus (MRSA), making it a valuable tool for research into antibiotic resistance and bacterial infections. Its application extends to studies focused on developing new antibacterial therapies and understanding microbial resistance mechanisms. -
Antibacterial Agent
ME-1228 is a sulfur-containing analog of OCP 9-176, functioning as a potent antibacterial agent. It demonstrates enhanced activity, being approximately twofold more effective than its precursor against a range of bacteria, including Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Providencia stuartii, Proteus vulgaris, and Serratia marcescens. Additionally, ME-1228 exhibits significant antibacterial activity against E. coli UB 1005 and Pseudomonas aeruginosa strains, with minimum inhibitory concentrations (MICs) of 0.25 μg/mL for both E. coli UB 1005 and P. aeruginosa K779K, and 1 μg/mL for P. aeruginosa E4. This compound is valuable for research into bacterial resistance mechanisms and the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Enaminomycin A is an anti-bacterial agent that demonstrates efficacy against a range of Gram-positive bacteria and some Gram-negative bacteria, while exhibiting weak activity against plant pathogenic fungi. Additionally, it has shown an inhibitory effect on the L-1210 leukemia cell line. This compound is valuable for research focused on antibacterial resistance and fungal infections, as well as potential applications in cancer studies. -
Bacterial Inhibitor
Sarothralin G is a potent antibacterial compound derived from Hypericum japonicum Thunb. It exhibits exceptional activity against Gram-positive bacteria, including Staphylococcus aureus, Bacillus subtilis, and Nocardia species. With its unique phenolic and aromatic acid structure, Sarothralin G demonstrates superior antibacterial efficacy compared to related compounds such as Sarothralen A, B and Saroaspidin A, B, C. This compound is valuable for research in antibiotic development and the study of bacterial resistance mechanisms. -
Anti-Bacterial Agent
Citreamicin ξ is an anti-bacterial agent that exhibits potent activity against both Gram-positive aerobic and anaerobic bacteria. This compound is particularly valuable in research focusing on bacterial infections and the development of novel antibacterial therapies. Its mechanism of action provides insights into combating resistant bacterial strains, making it a significant tool for microbiological studies. -
Anti-Bacterial Agent
4"-Demethylgentamicin C2 is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. Its mechanism involves inhibition of protein synthesis by binding to the bacterial ribosome, thereby disrupting essential cellular processes. This compound is useful for research applications focused on antimicrobial resistance and the development of new antibacterial therapies. -
Anti-Bacterial Agent
Pelagiomicin C is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. This compound is valuable for research in microbiology, particularly in studying bacterial resistance mechanisms and developing new antibacterial therapies. Its dual-targeting capability makes it a useful tool for researchers investigating a broad spectrum of bacterial infections. -
Anti-Bacterial Agent
Pyloricidin A1 is an antibiotic targeting Helicobacter pylori, derived from Bacillus sp. HC-70. It exhibits potent antibacterial activity specifically against H. pylori, making it a valuable tool for research into gastric infections. Pyloricidin A1 shows no antimicrobial activity against other bacterial species or yeast, highlighting its selectivity. -
Anti-Bacterial Agent
Kigamicin B is an anti-bacterial agent that exhibits potent activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), with minimum inhibitory concentrations (MICs) ranging from 0.025 to 0.78 μg/mL. This compound serves as a valuable tool for research in antibiotic resistance and the development of novel antibacterial therapies. Its efficacy against resistant strains highlights its potential application in microbiological studies and drug discovery efforts aimed at combating bacterial infections. -
AgrA Quorum-sensing Inhibitor
Apicidin D2 is a specific inhibitor of the accessory gene regulator A (AgrA), which plays a pivotal role in bacterial quorum sensing. This fungal metabolite demonstrates notable anti-virulence properties by effectively suppressing AgrA activation in Staphylococcus aureus, including methicillin-resistant strains (MRSA), without exhibiting biocidal effects. Apicidin D2 is a valuable reagent for research focused on understanding MRSA infections and developing strategies to combat quorum-sensing related pathogenicity. -
Anti-Bacterial Agent
5,10-Dihydrophencomycin methyl ester is an antibacterial agent primarily known for its activity against bacterial strains. It exhibits limited efficacy against Escherichia coli and Bacillus subtilis, making it a candidate for studies focused on the development of new antibacterial compounds. This reagent is useful in evaluating antibacterial resistance mechanisms and for potential applications in drug development within microbiological research. -
Antibacterial Agent
epi-Equisetin is a secondary metabolite known for its antibacterial properties. It exhibits significant activity against a range of bacterial strains, making it a valuable compound for research into antimicrobial therapeutics. This compound is suitable for investigations into bacterial resistance mechanisms and the development of new antibacterial agents. -
Anti-Bacterial Agent
Citreamicin η is an anti-bacterial agent that primarily targets Gram-positive aerobic and anaerobic bacteria. This compound demonstrates significant antibacterial activity, making it a valuable tool for research applications in microbiology and infectious disease studies. Its efficacy against a range of Gram-positive organisms provides insights into bacterial resistance mechanisms and potential therapeutic strategies. -
Anti-Bacterial Agent
Dioxamycin is an anti-bacterial agent primarily targeting Gram-positive bacteria. It demonstrates significant inhibitory activity against Staphylococcus aureus 209P, with a minimum inhibitory concentration (MIC) of 3.12 μg/mL. Additionally, Dioxamycin exhibits cytotoxic effects on various cancer cell lines, including L1210, P388, IMC, LX-1, and SC-6, with IC50 values ranging from 1.4 to 6.0 μg/mL, highlighting its potential applications in antibacterial and anticancer research. -
Anti-Bacterial Agent
Paulomycin A2 is an anti-bacterial agent that targets Gram-positive bacteria. It demonstrates inhibitory activity against Staphylococcus aureus strains that are resistant to penicillin, streptomycin, neomycin, and macrolide antibiotics. This compound is useful in research applications focused on developing new antimicrobial therapies and studying bacterial resistance mechanisms. -
Antibacterial Agent
NAI-802 is a novel lantibiotic that acts as an antibacterial agent. It exhibits potent activity against Gram-positive anaerobic bacteria, including Clostridium difficile, C. butyricum, C. perfringens, and Peptostreptococcus asaccharolyticus, with minimum inhibitory concentration (MIC) values ranging from 0.25 to 2 μg/mL. This compound is a valuable tool for research focused on the mechanisms of bacterial resistance and the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Saquayamycin A1 is an anti-bacterial agent known for its antimicrobial properties, exhibiting selective activity predominantly against Gram-positive bacteria. Additionally, it demonstrates inhibitory effects on leukemia P388 cells as well as Adriamycin-resistant P388 cells, making it a useful tool for studying drug resistance in cancer research. Its biological activity positions it as a potential candidate for further investigations in both anti-bacterial and anti-cancer applications. -
Anti-Bacterial Agent
Nisamycin is an anti-bacterial agent primarily effective against Gram-positive bacteria, exhibiting limited activity against certain Gram-negative bacteria and fungi. It demonstrates a weak cytotoxic effect, with an IC50 value of 4.8 μg/mL in mouse leukemia P388 cells. Nisamycin is suitable for research applications focused on studying bacterial infections and evaluating antimicrobial resistance mechanisms. -
Anti-Bacterial Agent
20-Deoxynarasin is an anti-bacterial agent that exhibits activity against Gram-positive bacteria, mycoplasma, coccidia, and certain viruses. This compound is relevant for research applications focused on evaluating antibacterial efficacy and growth promotion in various organisms. Its versatile biological activity makes it a useful tool in studies targeting infectious diseases and microbial growth regulation. -
Anti-Bacterial Agent
Amicenomycin A is an anti-bacterial agent that demonstrates potent activity against Gram-positive bacteria. This compound is useful in research focused on developing new antibiotics and studying bacterial resistance mechanisms. Its mechanism of action may provide insights into the efficacy and potential applications in treating bacterial infections. -
Anti-Bacterial Agent
Paulomycin B is an anti-bacterial agent that specifically targets Gram-positive bacteria. It exhibits significant inhibitory activity against penicillin-resistant Staphylococcus aureus, as well as strains resistant to Streptomycin, Neomycin, and Macrolide antibiotics. This compound is valuable for research focused on antibiotic resistance and the development of new therapeutic strategies against bacterial infections. -
Antibacterial Agents
Islandicin is an anthraquinone compound known for its antibacterial properties. Isolated from almonds, it exhibits significant activity against various bacterial strains. This compound is applicable in research focused on antimicrobial mechanisms and the development of new antibacterial agents. -
Anti-Bacterial Agent
Midecamycin A3 is a macrolide antibiotic that primarily targets Gram-positive bacteria. It exhibits potent antibacterial activity against various strains, while also demonstrating limited efficacy against Gram-negative bacteria, mycobacteria, and fungi. This compound is useful in microbiological research and the study of bacterial resistance mechanisms. -
Anti-Bacterial Agent
Senfolomycin B is an anti-bacterial agent that primarily targets Gram-positive bacteria and mycobacteria. It exhibits efficacy against penicillin-resistant Staphylococcus aureus, as well as bacteria resistant to Streptomycin, Neomycin, and Macrolide antibiotics. Additionally, Senfolomycin B demonstrates a weaker activity against Gram-negative bacteria, making it a valuable compound for research on antibiotic resistance and bacterial infections. -
Antibacterial Agent
MAC-0018315 acts as an antibacterial agent, primarily targeting bacterial cell wall synthesis. This compound exhibits significant inhibitory activity against a range of Gram-positive and Gram-negative bacteria. It is utilized in research applications focused on understanding bacterial resistance mechanisms and the development of novel antimicrobial therapies. -
Anti-Bacterial Agent
Roseorubicin A primarily targets Gram-positive bacteria and exhibits significant anti-mycobacterial activity. It is effective against leukemia L1210 cells, exhibiting an IC50 of 0.04 μg/mL. This compound serves as a valuable tool for research in antimicrobial efficacy and cancer studies. -
Antibacterial Agent
13-HPOT is a linolenic acid hydroperoxide that functions as an antibacterial agent by interacting with lipid components of bacterial inner membranes. It exhibits dose-dependent antibacterial activity in vitro against a range of pathogens, including Pectobacterium carotovorum, Pseudomonas syringae pv. syringae DC3000, and Xanthomonas translucens pv. translucens. This compound is valuable for research applications aimed at understanding bacterial stress responses and developing new antimicrobial strategies. -
Antibacterial Agent
S-25932 is a potent 4-quinolone antibacterial agent targeting gram-negative bacteria. It demonstrates significant antibacterial efficacy against various strains, including Enterobacter aerogenes, Enterobacter adhlomerans, Enterobacter cloacae, and Escherichia coli, with MIC90 values of 1.0, 2.0, 1.0, and 0.25 µg/mL, respectively. This compound is applicable for research into antibacterial therapies and microbiological studies. -
Anti-Bacterial Agent
Fluoropolyoxin L is an antibacterial agent that exhibits potent inhibitory activity against Escherichia coli and Streptococcus faecalis. This compound is valuable for research applications focused on understanding bacterial resistance mechanisms and the development of novel antimicrobial strategies. Its targeted activity makes it an essential tool for microbiological studies and antibiotic research. -
Anti-Bacterial Agent
Oxirapentyn is an anti-bacterial agent primarily targeting Gram-positive bacteria and Mycobacterium species. While its antibacterial activity is relatively weak, it serves as a valuable compound for exploring bacterial resistance mechanisms and developing new antimicrobial strategies in pharmaceutical research. Its applications include studying the effects of bacterial infections and assessing potential therapeutic approaches in the field of infectious diseases. -
Antibacterial Agent
(Rac)-LY 255262 is a pyrazolidinone derivative that functions as an antibacterial agent. It effectively inhibits bacterial growth, making it suitable for research into antimicrobial resistance and the development of new antibacterial therapies. This compound is particularly useful for studies focused on the mechanisms of bacterial infections and potential therapeutic interventions. -
Antibacterial Agent
Agrimol C is a phloroglucinol derivative that exhibits antibacterial properties, primarily targeting Staphylococcus aureus. It demonstrates a minimum inhibitory concentration (MIC) of 50 μg/mL, indicating its effectiveness against this pathogenic strain. Agrimol C is suitable for research focused on infections and the development of antibacterial agents. -
Antibacterial Agent
Antibacterial Agent 135 is a potent antibacterial compound targeting multiple bacterial strains. It demonstrates inhibitory activity against Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae, with an MIC greater than 64 μg/mL. This agent is valuable for research applications focusing on combating antibiotic-resistant infections and studying bacterial resistance mechanisms. -
Antibacterial Agent
4-Nitrosodiphenylamine is an antibacterial agent exhibiting significant activity against Erwinia amylovora, with an EC50 value of 5.715 mg/L. This compound is suitable for research applications focused on plant pathology and antibiotic development. Its effectiveness against specific bacterial strains makes it a valuable tool for studying antibacterial mechanisms and developing new therapeutic strategies.
