ABT-255 free base is an orally active anti-bacterial agent targeting diverse bacterial strains. It demonstrates strong in vitro efficacy against both drug-susceptible and drug-resistant Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) ranging from 0.016 to 0.031 μg/mL. Additionally, ABT-255 exhibits effectiveness against Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli, and has been shown to reduce viable counts of drug-resistant Mycobacterium tuberculosis in CF-1 mouse models. This compound is valuable for research aimed at understanding and treating pulmonary tuberculosis.
ABT-255 free base is an orally active anti-bacterial agent targeting diverse bacterial strains. It demonstrates strong in vitro efficacy against both drug-susceptible and drug-resistant Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) ranging from 0.016 to 0.031 μg/mL. Additionally, ABT-255 exhibits effectiveness against Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli, and has been shown to reduce viable counts of drug-resistant Mycobacterium tuberculosis in CF-1 mouse models. This compound is valuable for research aimed at understanding and treating pulmonary tuberculosis.
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