IMPDH-IN-1 is a selective inhibitor of bacterial inosine 5'-monophosphate dehydrogenase (IMPDH), targeting the catalytic domain of the enzyme. This compound demonstrates potent inhibitory activity against IMPDH from key bacterial pathogens, including Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli. It serves as a valuable tool for research into bacterial metabolism and the development of novel antimicrobial therapies.
IMPDH-IN-1 is a selective inhibitor of bacterial inosine 5'-monophosphate dehydrogenase (IMPDH), targeting the catalytic domain of the enzyme. This compound demonstrates potent inhibitory activity against IMPDH from key bacterial pathogens, including Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli. It serves as a valuable tool for research into bacterial metabolism and the development of novel antimicrobial therapies.
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